查询词典 mesenchymal

Objective To investigate the factors of growth and cardiogenic differentiation of rat mesenchymal stem cells in vitro.

目的 研究大鼠骨髓间充质干细胞的体外培养及向心肌样细胞转化的条件。

OBJECTIVE: After purification and amplification in vitro, the bone marrow mesenchymal stem cells were induced into chondrocytes, and then implanted them at the bottom of nano-hydroxyapatie/chitosan scaffold for combined culture. The aim was to investigate the feasibility of them used in tissue-engineered chondral composite graft.

目的：将体外提纯、扩增的骨髓间充质干细胞诱导成软骨细胞，将其接种于穿&靴&的纳米羟基磷灰石/壳聚糖支架的底部上联合培养，探索其用于组织工程软骨复合体的可行性。

In summary, hyaluronic acid and autologous synovial fluid induces chondrogenesis of equine mesenchymal stem cells, which encourage tissue engineering applications of MSC in chondral defects, as the natural environment in the joint is favorable for chondrogenic differentiation.

总之，透明质酸和自体关节液诱导马的间充质干细胞的软骨形成，这鼓励组织工程在软骨缺损修复中应用间充质干细胞，因为关节自然环境是有利于软骨形成分化。

After the expression completed, BMP and TGF－β were distributed in the chondral matrix and granulation tissues. The bFGF was mainly distributed around non－active mesenchymal cells in the granulation tissues.

表达后BMP、TGF-β较均匀分布于软骨基质以及肉芽组织间质中，bFGF 主要分布于肉芽组织中非活跃的间质细胞周围。

Key words: umbilical cord blood;mesenchymal stem cells; chondroblast; transforming growth factor-β1

脐带血；间充质干细胞；成软骨细胞；转化生长因子-β1

Objective To explore whether mesenchymal stem cells could be isolated from human umbilical cord blood and would be able to differentiate into chondroblast in vitro.

目的：探讨人脐带血间充质干细胞存在及体外向成软骨细胞分化的可能性。

Bone induction is an important theory in the early 20th century. Urist found that bone morphogenetic protein could promote mesenchymal cell to differentiate into osteoprogenitors and chondroblast in 1965, thence many scholars went in for the significant work in this research field.

诱导成骨是近代发展的重要理论，Urist首先提出间充质细胞在骨形态发生蛋白的作用下可向成骨和成软骨方向分化，此后国内外很多学者在该领域进行了广泛深入的探索。

In SMC group, relative stable of the both ends of fracture reduce unnessary repeated stimulation of injury, and at same time, axio-stress advantageous for preosteoblast and mesenchymal cell transmit to osteoblast and chondroblast. Material and design superiority of SMC form unique internal mechanical environment, and which benefit for bone healing. The study took deep investigation of SMC on fracture healing.

上述结果证实：SMC内固定可对骨折端施加主动的、持续的轴向应力刺激，形成沿长骨骨干轴向的成骨导向力值，配合环抱翼的把持作用，形成了区别于CP、IN的独特的稳定、有效的机械内环境，骨折端的相对稳定减少了不必要的损伤再刺激，同时持续轴向应力有利于成骨祖细胞、间充质细胞向成骨细胞和成软骨细胞转化、促进了成骨诱导过程的发生与发展，加快了骨折愈合的修复与重建。

RESULTS: Twelve days after mandibular vertical functional positioning the condylar height increased. Nine days after mandibular vertical functional positioning the thickness of prechondroblast layer and chondroblast layer increased significantly compared with control groups. However the thickness of hypertrophic layer decreased significantly after 6 days' mandibular repositioning. No change was found in the thickness of mesenchymal layer during the experimental period.

结果：下颌垂直向功能性移位后12d，髁突高度较对照组显著增加，前斜面更倾斜；髁突后上区前成软骨细胞及成软骨细胞层厚度在实验第3~6天无明显差异，第9天开始出现显著变化，实验组较对照组显著增厚，这种变化持续到实验第12天；肥大软骨细胞层厚度在实验第3、9、12天，实验组与对照组无显著差异，在实验第6天较对照组显著减少，间充质细胞层变化不大。

Bone marrow containing hematopoietic stem cells has already been known , theses another group stem cells exists in bone marrow named mesenchymal stem cells. MSCs retain the potentiality of differentiating into osteoblast, chondroblast, adipoblast, tendonblast, myoblast, cardiomyoblast, neuron, etc , which displays a bright prosperity of its use in tissue enigeering, wound healing , cell transplatation and gene therapy. MSCs can be obtained and expanded easily compared to ESC without any problems of morality , law and ethic , immunology.

最早在130年前，德国病理学家Cohnheim在研究创口愈合时就推测在创口愈合过程中出现的部分细胞可能来自骨髓。20世纪70年代，Friendenstein发现一小部分骨髓中贴壁最牢固的细胞经数此传代后形成独特的纺锤形外观，具有形成成骨细胞或软骨细胞的能力。80年代以来，许多研究小组进一步证实了Friendenstein分离到的这些细胞是多能的，在体外特定诱导条件下，可以分化为成骨细胞、软骨细胞、脂肪细胞、成肌细胞、神经元等，被称为骨髓间充质干细胞(Bone MarrowMesenchymal Stem Cells，MSCs)。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。