查询词典 melanoma

The influence of azelaic acid on melanin synthesis and tyrosinase activity of human melanocytes and murine B16 melanoma cells were studied.

结果 壬二酸作用于人表皮黑素细胞后，可见细胞树突明显减少；壬二酸作用于B16细胞后，细胞形态无明显改变。

Abstract〕 Objective To study 23-hydroxyl betulinic acid induced apoptosis and growth inhibition of B16 melanoma cell in vivo and in vitro.

摘要〕 目的研究23-羟基桦木酸对体内、外B16黑色素瘤细胞生长的抑制及诱导凋亡作用。

And a birch bark compound, betulinic acid, is being tested as a treatment for melanoma and other serious diseases.

一、桦树皮大院桦木酸，正测试作为治疗黑素瘤和其他严重疾病。

Key words〕 23-hydroxyl betulinic acid;B16 melanoma cell;apoptosis

关键词〕 23-羟基桦木酸；黑色素瘤细胞；细胞凋亡

Betulinic acid, a pentacyclic triterpene, has recently been reported to possess antitumor activity against cultured human melanoma cells.

1995年，人们首次发现了白桦酯酸的抗黑色素瘤活性以及作用的选择性，被称为是很有前景的抗肿瘤候选药物。

Methods MTT assay,electronic microscopy,flow cytometry and tumor volume assay were used to examine the effect of 23-hydroxyl betulinic acid on B16 melanoma cell line.

应用MTT分析，电镜观察，流式细胞仪，肿瘤体积大小测定等方法，对23-羟基桦木酸诱导黑色素瘤细胞进行检测和观察。

Furthermore, the ability of betulinic acid to induce apoptosis in melanoma and other cell types and the favoral therapeutic index suggests that betulinic acid is an attractive and promising antitumor agent.

虽然白桦酯酸存在于很多植物种类中，但其普遍含量很低，由于其巨大的研究价值，仅靠植物提取已经不能满足越来越多的研究需求，与白桦酯酸结构很相近的化合物白桦酯醇，在白桦树皮中含量高于10%，而白桦又是北半球数量丰富的树种。

A number of studies have suggested that apoptosis and its regulation plays an important pathogenic role in the chemoresistance of human melanoma.

现有研究已证实凋亡及其调节因子是决定恶性黑素瘤耐药的重要机制。

Our research has showed that Mcl-1 AS-ODN can partially reverse the chemoresistance of melanoma.

我们前期工作也显示Mcl-1反义寡核苷酸可部分逆转恶性黑素瘤的耐药性。

Objective To evaluate the expression and clinical significance of C-myc protein in choroidal malignant melanoma.

目的 探讨C-myc致癌蛋白在脉络膜恶性黑色素瘤中的表达及其临床意义。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。