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OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数，优化给药方案，设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式，CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发，在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物，适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上，结合病人个体特征，以1，2个血药浓度作为反馈，即可拟合估算个体药动学参数，优化给药方案结论经初步应用，CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

The torque is measured, and can be converted to apparent viscosity after calibration.

旋矩是可以测量的，在校正后并可转换成可见的粘度。

However, the price rise must be commensurate with China's purchasing power as measured by its wages.

但是，这些商品的价格上升幅度必须于中国的购买力相匹配，中国的购买力一般由其工资水平来衡量。

The burn rate was measured and found to be normal, consistent with that of previous batches.

烧伤率是衡量和发现是正常的，一致的，与以往的批量生产。

It can not be measured in terms of money.

这是不能用金钱衡量的。

"We believe that all theological beliefs must be measured by the living Word, judged by its truth, and whatsoever is unable to pass this test, or is found to be out of harmony with its message, is to be rejected."

"我们相信所有的神学信仰都必须用活泼的圣言来衡量，用其真理来判断，并且只要通不过这种试验，或者是发现与其信息不符合的，无论如何都应该被弃绝。"

The measured transmittance of the new beam splitter is about 85% with measurement error of about 0.91%.

通过测量其透射比得到新设计的分束器的透射在85%左右，测量误差在0.91%左右。

In this experiment, the content of total flavones in soybean, black bean and soybean sprout were measured using the spectrophotometric method, and distilled water, 70% methanol, 70% ethanol and 70% acetone were chosed as the extraction solvents.

以蒸馏水、70%甲醇、70%乙醇、70%丙酮作为提取剂，用分光光度法测定黄豆、黑豆、黄豆芽中总黄酮的含量。

Methods Explant culture of human nasal epithelial cells. Ciliary beat frequency was measured by digital high-speed microscope.

人鼻腔黏膜的组织块培养法，应用显微高速成像技术测量纤毛摆动频率。

The velocities of ultrasonic wave and rock drillability are measured in perpendicular and parallel directions of the bedding plane of core samples which were cut from the approach hole of Chinese continental scientific drilling. Rock drillability index and P-wave velocity anisotropy coefficient are calculated from the testing data; and the results are discussed.

通过室内实验分别测定了岩芯垂直于和平行于地层层面方向的可钻性及声波速度，得到了岩石可钻性各向异性指数和波速各向异性系数，并对结果进行了讨论。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。