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During this group patient is changing cure, 1.2 harmful response all differ of degree have the whole body difference of lack of power, accept, epigastrium bilges frowzily feeling, have among them constipation and / or defecate secret person 97, occupy 38.8%, gastric bowel path reacts person 79, occupy 31.7%, the person that marrow is restrained 31, occupy 12.4%, oral cavity ulcer person 18, occupy 0.7%. 2 before changing cure, nurse 2.1 elaborate psychology nurse, eliminate patient of mental obstacle old age to have in all many sided such as nerve, physiology, thinking not at patient of other age group, together with is mixed to the fear of cancer distressed mood, cause very easily angst and / or depressed mental state.

其中食管癌173例(术后138例)，贲门癌42例(术后27例)，乳腺癌16例，肺癌11例(非小细胞型肺癌3例)，非柯杰金氏淋巴瘤7例。1.2不良反应本组患者在化疗期间均不同程度的有周身乏力、纳差、上腹部闷胀感，其中有便秘和/或大便秘者97例，占38.8%，胃肠道反应者79例，占31.7%，骨髓抑制者31例，占12.4%，口腔溃疡者18例，占0.7%。2化疗前护理2.1精心心理护理，消除精神障碍老年患者在神经、生理、思维等诸多方面有别于其它年龄组患者，加之对癌症的惧怕和忧伤情绪，很易引发焦虑和/或抑郁的心境。

MATERIALS AND METHODS: The health-preserving cigarettes were made by certain Chinese herbal medicine such as piper sarmentosum Roxb. We made these cigarettes into a smoke liquid of normal saline solution as an experimental material to do an acute toxicity test in mice. A micronucleus test of mice bone marrow polychromatophilic erythroblast and an Ames test were performed.

材料与方法：在香烟中加入中草药假药等制成中草药保健香烟，用该香烟制得生理盐水烟雾液为实验材料，进行小鼠急性毒性实验、小鼠骨髓嗜多染红细胞微核试验和Ames试验。

The results revealed that marrow cells were younger, the diameters were larger. During erythrogenisis, the degree of decreased diameters became large. This phenominia was more apparent at the mature peried of mediate erythroblast or late erythroblast.

结果提示：灰尾兔骨髓内愈幼稚的细胞直径愈大，在成熟过程中直径变小的幅度逐渐加快，此现象在中幼红细胞发育成晚幼红细胞时最为明显。

Results The megakaryocyte and platelet of 112 cases hemopathy marrow smear with acetal phospholipids staining were all positive, the plasmas cell in anaemia were positive, the erythroblast of aplastic anemia positive, the lipocyte in thrombocytopenic purpura positive, and the other cells all negative.

结果］112例血液病骨髓涂片缩醛磷脂染色中的巨核细胞和血小板均为阳性，贫血中的浆细胞为阳性，再生障碍性贫血中的幼红细胞为阳性，血小板减少性紫癜中的脂肪细胞为阳性，其余各种细胞均呈阴性反应。

Results: 48 h after treatment, most of the patients had a marked improvement in irf and ret (p＜0.05), and irf showed a more significant increase. moreover, the value before treatment and 48 h after treatment of irf had no overlap; irf and ret were further increased after 1 week; after 12 weeks irf%, hct, ret, rbc and hb were significantly increased than before treatment, bone marrow erythrocytic series proliferation was more active than that before treatment, each kind of erythroblast ratio and the percentage of total erythrocytic series were significantly increased, especially late erythroblasts proliferation.

结果：治疗过程中大部分患者在epo注射48 h后irf、ret升高（p.05），irf升高更为显著，且irf在给药前和给药48 h后的数值无重叠区，1周后irf、ret进一步升高，12周时irf、hct、ret、rbc、hb均比用药前显著增高，骨髓红系增生较治疗前明显活跃，各类幼红细胞比率及总红系所占百分数均显著升高，其中以晚幼红细胞增生最为明显。

These were 85.7% of patients with myelocytes and premonocyte, 52.4% of patients with erythroblast in their blood smear respectively. All of the bone marrow showed active or significantly active proliferation. The median percentage of erythro??lineage, myeloblast of NEC and displasia were (58.3±8.0)%,(58.0±18.4)% and 66.7% respectively, that is different from typical AML.

外周血分类显示85.7%患者有幼稚粒细胞和幼稚单核细胞，52.4%患者有幼稚红细胞和有核红细胞；骨髓涂片显示骨髓增生活跃或明显活跃；红系细胞占58.3±8.0%，原始粒细胞占NEC 58.0±18.4%；66.7%患者有病态造血，与典型AML不同。

These changes occur in many tissues but are best known in the precursors of red cells in the bone marrow which is said to exhibit megaloblastic erythroblastosis. In addition to nuclear enlargement in megaloblasts there is increased amount of cytoplasm, cytoplasmic basophilia due to excessive RNA and premature haemoglobinisation as judged by the immature state of the nucleus.

这些变化出现于许多组织，但在巨成红细胞生成的骨髓红细胞前身中最好识别，巨成红细胞除核增大外，胞浆量增加，由于RNA过多致胞浆呈嗜碱性和早熟的血红蛋白形成，这是根据其核的不成熟状态而作出的判断。

Features of the related myeloproliferative disorder included isolated erythrocytosis, distinctive bone marrow morphology, and reduced serum erythropoietin levels.

相关骨髓增生碍的主要特征为：独立的红细胞增多，特征性的骨髓心态学以及血清中促红细胞生成素的减少。

Results After the therapy, the sTfR and erythron increased significantly, but bone marrow iron deposits decreased progressively as HCT increased. The sTfR had a apositive correlation with RBC (r=0.632, P.01) and positive correlation with Hct (r=0.757, P.01) and positive correlation with E%(r=0.775, P.01). No correlations were observed among sTfR and other parameters.

结果 患者治疗后sTfR显著增高(P.01)；而骨髓外铁、铁粒幼细胞、SF均显著降低；红系增生较治疗前明显活跃(P.01)。sTfR与RBC呈正相关(r=0.632， P.01)；与Hct呈正相关(r=0.757， P.01)；与骨髓E%呈正相关(r=0.775， P.01)；与其他参数无相关性。

There is positive correlation between bone mineral density and ratio of trabecular partition to ROI area, and negative correlation between bone marrow partition to ROI area or Euler number.

跟骨高分辨CT图像能客观反映糖尿病非胰岛素治疗患者跟骨微观形态学方面的改变。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。