查询词典 marrow

Objective: To study osteogenic capability of rabbit bone marrow stromal cells and biological characteristical identification in vitro in order to explore the appropriate methods of osteoblast culture in vitro and to select an idea source of seed cells for bone tissue engineer .

目的：研究兔骨髓基质细胞在体外培养条件下的成骨能力及生物学特性，探讨简便易行的成骨细胞体外培养方法，为组织工程选择理想的种子细胞来源。

The characteristical time-dependent expression of transcriptional factors HNF4α, C/EBPα, and C/EBPβ during the hepatocyte differentiation by bone marrow stem cells demonstrates that the expressions of these transcriptional factors are closely related to the initiation and maintenance of hepatocyte differentiation.

结论在肝细胞分化过程中，转录因子HNF4α、C/EBPα和C/EBPβ呈特征性时序表达，表明骨髓间充质干细胞在向肝细胞分化时，肝细胞相关转录因子的表达与细胞分化的启动和维持密切相关。

Objective: To study osteogenic capability of rabbit bone marrow stromal cells and biological characteristical identification in vitro in order to explore the appropriate methods of osteoblast culture in vitro and to select an idea source of seed cells for bone tissue engineer.

目的：研究兔骨髓基质细胞在体外培养条件下的成骨能力及生物学特性，探讨简便易行的成骨细胞体外培养方法，为组织工程选择理想的种子细胞来源。方法：取新西兰白兔骨髓液经离心后得骨髓单个核细胞，以1× 106／ml的细胞浓度进行培养，经传代培养，选择条件培养液培养(1640完全培养液中加入地塞米松10-8Smol／l，β-甘油磷酸钠10mmol／l，VitC 50μg／ml)作为骨髓基质细胞增殖和成骨的调节因子，通过倒置显微镜、HE染色、扫描电镜、碱磷酸酶(alkaline phosphatase，ALP)测定、Ⅰ型胶原免疫组化染色和四环素荧光钙染色等手段对获得的细胞进行生物学特性研究。

BACKGROUND: Early research indicates that chemotactic factors involved in chemotaxis of bone marrow mesenchymal stem cells in vitro.

背景：早期研究表明趋化因子参与骨髓间充质干细胞的体外趋化，确定骨髓间充质干细胞体内迁移的分子机制，对其介导的细胞治疗中枢神经系统损伤和疾病有重要作用。

He was chilled to the marrow.

他是冷到了骨髓。

Methods The bone marrow cells of pure Kumming species of mice were used as experimental material in which the micronucleusand sister chromatid exchanges induced by cyclophosphamide were used as an index.

方法以昆明纯种小鼠的骨髓细胞为实验材料，用公认的诱变剂环磷酰胺诱发的微核率和姐妹染色单体互换频率为指标，研究EGCG对CP诱导小鼠骨髓细胞MN和SCE的影响。

Results This material had no cytoxicity,no s en-sitivity,no obvious haemolysi s,an d no mutagencity in Ames test,mice marrow micronucleus test and chromo so me aberration test of mammalian cell in vitro.

Ames试验、小鼠骨髓细胞微核试验和哺乳细胞体外染色体畸变试验结果显示材料无致突变性。结论Evergel人工髓核材料具有良好的生物相容性，可以进行临床应用。

RESULTS: Symptoms of all the patients undergoing bone marrow stem cell transplantation were alleviate to a certain extent. Edema and feeling of ponderosity were moderated evidently. Cicatricle was softened. The difference of affected and unaffected sides its upper limb dropsy patients was (9.2±1.4) cm before treatment, and (3.5±0.9) cm after 3 months of treatment. The difference of affected and unaffected sides in lower limb dropsy patients was (8.2±1.3) cm before treatment, and (3.7±0.6) cm after 3 months of treatment.

结果：所有接受自体骨髓干细胞移植的患者，症状均有不同程度的改善，肢体肿胀明显消退，肢体沉重感减轻，瘢痕软化，上肢水肿患者术前健侧与患侧差值为(9.2±1.4)cm，治疗后3个月为(3.5±0.9)cm，下肢水肿患者术前健侧与患侧差值为(8.2±1.3)cm，治疗后3个月为(3.7±0.6)cm。

Objective To observe osteogenesis of percutaneous autogenous bone marrow into cicatrix of bone defect.

目的 观察经皮自体骨髓移植在骨缺损瘢痕组织内的成骨作用。

Methods 18 rabbits were used to observe the osteogenesis of percutaneous autogenous bone marrow into cicatrix of bone defect.A 1cm bone defect model was made in each side of the radius.

选健康家兔18只，建立双侧桡骨中段骨及骨膜缺损1cm模型，两骨断端髓腔用骨蜡封闭。6周后，实验侧桡骨骨缺损区经皮注射自体红骨髓2ml；对照侧桡骨骨缺损区注射自身外周血2ml。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。