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By using Morris Maze task,The results indicated the learning and memory impairment was continuously maintained by MA-induced neurotoxity,PF_(11) significantly antagonized the learning and memory impairment by MA-induced neurotoxicity, Motor incoordination was studied by using the rotating rod method in mice,PF_(11) markedly alleviated the injury induced by MA.using HPLC-ECD,there were markedly decrease the contents of DA,DOPAC,HVA and 5-HIAA,PF_(11) markedly antagonised decrease of DA in MA-induced neurotoxicity.

在Morris水迷宫空间辨别性学习记忆实验中,甲基苯丙胺中毒小鼠找到平台的潜伏期明显延长,PF_(11)沈阳药科大学硕士学位论文中文摘要能显著缩短延长的潜伏期。转棒实验表明,甲基苯丙胺中毒小鼠运动协调性显著降低,而PF;;能桔抗小鼠运动协调性的降低。甲基苯丙胺中毒小鼠大脑内多巴胺及其代谢产物DOPAC、HVA含量明显降低,另外,5一羟色胺的代谢产物5-HIAA明显降低,而PF;;与甲基苯丙胺联合给药小鼠大脑内DA、HVA的含量显著升高。这些结果提示PF;通过影响多巴胺神经系统而桔抗甲基苯丙胺神经毒性的作用。

The leading allergen was dirt and next were acarid, dog hair, roach and pineapple. The total positive items was 156 and inhale allergens accounted for 62.8%. The positive rate of inhale allergens of 3~6 and 6~14 years old group was markedly higher than those of and 1~3 years old group. But to food allergens, the 3~6 and 6~14 group was markedly lower than the latter. There was 24.6%(32/130) patients founded more than 3 allergens.

阳性率最高的过敏原为屋尘,占65.5%,其次为户尘螨、狗毛屑、蟑螂和菠萝。3~6岁和6~14岁组的吸入性过敏原阳性率显著高于<1岁和1~3岁组(P.05),而食入性过敏原阳性率则显著低于后者。24.6%(32/130)患儿检出3种以上过敏原。

Moreover, compared with 1 mmol/L and 3 mmol/L, 5 mmol/L treatment more significantly slowed down the maturation and consenescence process of muskmelon. Meanwhile, compared to the calcium nitrate treated for 4 h and 8 h, the discs treated for 12 h were more apparently promoted or inhibited based on above maturation and consenescence physiological parameters; however, with the prolonging of treated time to 24 h, the activities of POD, SOD and CAT dropped markedly, as well as the inhibition of synthesis of soluble protein, and the increased speed of electrical conductivity and LOX activity were reduced markedly.

与1 mmol/L和3 mmol/L的硝酸钙相比,5 mmol/L的硝酸钙处理更能显著延缓果实的衰老进程;与处理4 h和8 h相比,处理12 h硝酸钙对以上各成熟衰老指标的促进或抑制作用效果更加显著,但是随着处理时间的延长至处理24 h时,POD、SOD、CAT活性反而下降,对可溶性蛋白的合成、外渗电导率和LOX活性升高速度的抑制效应显著降低。

Results: Typical DNT was located in cortical or subcortical white matter, with cystic or semiliquid structures. On MR images appeared as lesions with inhomogeneous signal intensities, consistent MR feature in all cases were the presence of one or multiple areas of moderately or markedly reduced T1-signal and markedly or moderately increased T2-signal, with moderate enhancement.

结果:典型的DNT位于皮层或主要位于皮层区,肿瘤以囊性成分为主、病灶在T1WI为低信号,T1WI为高信号,其ADC值增高,FLAIR序列上病灶边缘和分隔为高信号改变,增强扫描病灶实质结节或分隔可见轻度强化。

Spraying KCL solution every other day for 15 days start from late flowering, results showed that nitrate content in the leafs and stems were markedly reduced, Nitrogen redistributed to silique and rapeseed were efficiently promoted, nitrate reductase activity in the leaf were markedly increased. The differences of the same species which under different treatment are more serious, and the differences of the different species which under the same treatment are more significant.

结果表明,喷施氯化钾溶液能有效降低开花期和收获期油菜茎叶硝酸盐含量,与喷施硫酸钾溶液和清水相比达到了显著水平;有效促进了氮素向角果和籽粒分配,显著增强了油菜角果初期叶片硝酸还原酶的活性;同一品种不同处理之间的差异比较显著,品种之间处理后的差异也比较明显。

The content of DNA、RNA and total nucleic acid sostenuto reduced after anthesis,thereinto the rate of RNA content reduction was markedly quicker than DNA's,thereduction of DNA and RNA content markedly related to the rising of Dnase and Rnaseactivity.

小麦旗叶总核酸、DNA和RNA含量在开花后持续降低,其中RNA含量的降低显著快于DNA,DNA和RNA含量的降低与DNase、RNase的活性上升密切相关。

This paper describes the succulence of organs of Suaeda salsa seedlings treated with different salts. The growth of the seedlings was markedly enhanced by NaCl but markedly inhibited by NaF treatment. The degree of succulence was the greatest in leaves, second in stems and third in roots of seedlings treated with NaCl.

用不同的钠盐和含Cl-的盐处理盐地碱蓬幼苗后,测定不同器官的肉质化及相关生理指标,结果表明:NaF处理明显抑制盐地碱蓬幼苗的生长;NaCl处理下生长最好,其中叶片的肉质化程度显著高于对照,正在伸展茎次之,而根则不明显;其次是NaHCO3,肉质化程度也明显高于对照;CaCl2和KCl处理下肉质化程度都与对照相似;MgCl2处理下叶片的肉质化程度明显低于对照。

The mothod is simple, quick, acurate. In all of the samples, the contents of echinacoside is markedly more than that of acteoside, the content of the two active component in the wilding is higher than that in the planting. The content of sample in the different sizes gradually increase from the big to the small, and the contents of samples collected from the different hosts vary markedly. These results are useful for the quality evaluation of medicinal materials of C. tubulosa .

本法用于管花肉苁蓉的测定简便、快速、灵敏、重复性好,所测样品中有效成分松果菊苷比毛蕊花糖苷的含量均高,野生种的2种有效成分含量均比栽培种的高,将样品以个体长度分成大、中、小3种不同样品,所测结果表示其含量按大、中、小依次增加,不同寄主间的含量差异很大,为评价管花肉苁蓉的药材质量提供一定的依据。

Result] Nvjin capsule can markedly improve mouse pain tolerance, inhibit ear swelling, shorten cuttail blooding time and obviously shorten TT and Fbg, but has little influence on PT;can markedly raise platelet collection rate.

结果]女金胶囊可明显提高热板法致痛的小鼠痛阈;对二甲苯所致小鼠耳廓肿胀有明显的抑制作用,还能显著缩短小鼠断尾出血时间;显著缩短TT和减少Fbg水平,而对PT影响较小;显著升高血小板聚集率。

Dealcoholization temperature markedly influences the surface area and porosity of the resultant MAO-supports. When the support was pretreated at lower or higher temperature, the corresponding MAO-support shows very low surface area;2.XRD and IR analyses indicate that MAO has reacted with the residual ethanol in the supports, which is an important manner to get MAO fixed on the carrier. Morever, XPS analyse indicates that MAO can also be coordinated with MgCl_2, which is another way to get MAO fixed on the support;3.ICP and EDX analyses indicate that dealcoholization temperature not only determined the element content on the solid catalyst, but also influences the element distribution on the carrier;4.The activities of the supported phenoxy-imine catalysts and the properties of resultant polymers are strongly dependent on the dealcoholization temperature. The support (MSP-5) obtained by treating MgCl_2·2.56C_2H_5OH at 160℃for 4 h, then modified by MAO is very effective for immobilizing complex 3, the resultant solid catalyst (MSPC-5) shows very high activity in ethylene polymerization, and its kinetics of polymerization is stable during the reaction process. Finally, PEs with spherical morphology and high bulk density (over 0.35g/ml) were obtained, without reactor fouling;5.In this work, polymerization conditions such as alkylaluminums, Al/Zr ratio, temperature and H_2 had a pronounced effect on the activity of MSPC-5 and properties of PE;(3). New MgCl_2-Supported Single-Site Catalysts for Ethylene PolymerizationIn this work, a kind of new MgCl_2 support was obtained by anhydrous MgCl_2 co-milled with solid MAO, and it is a creative contribution. Then some single-site catalysts were supported on the new MgCl_2 support, and the resulted solid catalysts were tested in ethylene polymerization, the results indicated that:1.XRD and IR analyses indicate that MAO does be coordinated with MgCl_2, which is in good agreement with the results obtained by XPS;2.co-mlling time had no obvious effect on the texture of support after 12 hours;3.In this work, MgCl_2 was co-milled with solid MAO for different hours, and then complex 3 was supported on these co-milled supports. It was found that co-milling time markedly influences the activity of solid catalysts, but it had negligible effect on the kinetic profile and the properties of resultant PE.

XPS研究结果表明,MAO不仅仅只和乙醇作用,MAO还与MgCl_2本身有一定的作用,这是一个极为重要的发现;3、通过ICP和EDX表征,发现载体的脱醇温度直接影响着元素在固体催化剂中的含量及分布;4、脱醇温度极大地影响着负载苯氧基亚胺类催化剂的活性和聚合物的性能,特别是原始载体经160℃活化4小时制备得到的固体催化剂MSPC-5的活性明显高于其他脱醇温度条件下制得的固体催化,并且催化剂寿命长,表现出稳定的动力学行为,最终获得了高堆密度(大于0.35g/ml)的球形聚乙烯颗粒;5、本文选择MSPC-5为研究对象,考察了聚合反应参数对催化剂的活性及其聚合物的影响,研究发现:不同的烷基铝对催化剂具有非常重要的影响,特别足TIBA对MSPC-5的助催化活性最高,烷基铝的加入量有一个较佳值,聚合温度为80度时活性最高,H_2的加入使催化剂的活性明显降低且聚合物的分子量也减小;、新型氯化镁载体负载单活性中心催化剂催化乙烯聚合本文创造性采用固体MAO与无水氯化镁直接进行共研磨,制备出了一种的新型的氯化镁载体,并将该载体用于多种单活性中心催化剂的负载化研究,研究表明:1、通过BET、XRD的表征,再次证实了MAO与MgCl_2之间具有直接作用,与XPS的研究结果相一致;2、当研磨时间高于12小时时,延长研磨时间对载体的结构没有显著的影响;3、将配合物3负载于共研磨时间不同的一系列载体上,乙烯聚合结果表明,尽管共研磨时间对负载催化剂的活性具有明显的影响,但是它对聚合物的性能以及催化剂的影响不明显。

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