查询词典 lympho-adenoma

Objective To explore the role of nuclear factor-κB in the signal conduction of protein kinase C regulated proliferation, apoptosis and expression o f Th2 cytokines - interleukin-4 (IL-4) and interleukin-5 (IL-5) of T lympho cytes in the bronchial alveolus lavage fluid.

目的探讨核因子-κB在蛋白激酶C对豚鼠哮喘模型T淋巴细胞功能调控的信号传导中的作用。

Draining lymph nodes isolated from the BALB/C mice immunized with rabbit skin collagen Type Ⅲ accord- ing to a rapid immunization protocol, the lympho- cytes were fused with the myeloma cell line NS-1, 3 out of total of 201 growing hybridomas we obtained were producing collagen Type Ⅲ reactive antibodies after 3 limited dilution clones performed.

本实验采用快速免疫的方法用兔皮肤Ⅲ型胶原免疫BLAB/C小鼠，取淋巴结的细胞与小鼠骨髓瘤细胞NS-1融合，240孔中201孔有杂交瘤生长，用ELISA检测有6孔反应阳性。选3孔生长良好，抗体浓度高的细胞进行有效的有限稀释法克隆3次，获3株分泌抗Ⅲ型胶原单克隆抗体的杂交瘤细胞。其中二株属IgG2b，一株为IgG1。

In this work, it was found that MT at the concentrations of 〓 and 〓 mol·〓 could enhance the proliferation in rats and mice thymic lympho- cytes and human PBL as well as enhancing the proliferation in AA rats, 11 months mice and Mor-dependent mice thymic lym- phocytes, and RA patients PBL, and what was more that MT at a lower concontrations had a marked up-regulation on the above decreased lymphocytes proliferation.

结果表明，依赖组小鼠痛阈下降，跳跃次数增加，肛温降低，伴有胸腺细胞增殖能力的低下，Mor依赖小鼠的脑和血浆甲硫氨酸脑啡肽亦明显降低。ig MT（30、90 mg·〓×7d）能明显提高依赖性小鼠的痛阈，减少跳跃次数，恢复其肛温，阻止Mor对淋巴细胞功能的抑制，并能维持脑、血浆Met-Enk接近正常对照水平。

Results The activation of NF-κB, proliferation response, and expression of IL-4 and I L-5 mRNA and protein in T lymphocytes stimulated by PMA were significantly hig her than those of their blank control (P.01), while those indexes of T l ymphocytes stimulated by PMA and PDTC simultaneously were significantly lower th an those stimulated by PMA alone (P.01). The apoptotic index of T lympho cytes stimulated with PMA were significantly lower than that of their blank cont rol (P.01), and the apoptotic index of asthmatic guinea pig T lymphocytes stimulated with PMA and PDTC simultaneously were significantly higher than that stimulated by PMA alone (P.01). The significant positive correlations w ere found between the activation of NF-κB and the proliferation (r=0.64, P.001), and the expression of IL-4 and IL-5 mRNA and protein of T lymph ocytes, respectively (r=0.55-0.68, P.001). There was also signific ant negative correlation between the activation of NF-κB and apoptosis of T l ymphocytes (r=0.62, P.001). Conclusions NF-κB may participate in the signal conduction of PKC regulated proliferation, apoptosis and expression of IL-4 and IL-5 of T lymphocytes in asthma.

结果加入PMA培养的哮喘组T淋巴细胞NF-κB的活化、细胞增殖反应、IL-4和IL-5的mRNA和蛋白质的表达均显著高于其空白对照(P.01)，而同时加入PMA和PDTC培养的哮喘组T 淋巴细胞以上指标均显著低于只加入PMA培养的哮喘组T淋巴细胞(P.01)；加入PMA 培养的哮喘组T淋巴细胞的凋亡指数显著低于其空白对照(P.01)，而同时加入PMA 和PDTC培养的哮喘组T淋巴细胞凋亡指数显著高于只加入PMA培养的哮喘组T淋巴细胞(P 。01)。T淋巴细胞NF-κB的活化与增殖反应呈显著正相关(r=0.64，P.00 1)，与IL-4和IL-5的mRNA和蛋白质的表达也均呈显著正相关(r=0.55-0.68，P 。001)，而与凋亡指数呈显著负相关(r=-0.62，P.001)。

To investigate the role of prophylactic lamivudone in reducing the incidence and severity of hepatitis B in lympho- ma patients who were HBV carriers and received chemotherapy.The prophylactic lamivudine group consisted of 40 patients who were treated with oral lamivudine before and until at least 8 weeks after chemotherapy.The historical control group con- sisted of 116 patients who underwent chemotherapy without lamivudine treatment.

探讨慢性HBV携带的淋巴瘤患者化疗前预防应用拉米夫定在减少化疗后肝炎发生率以及严重程度方面的作用。40例患者化疗前及整个化疗期间口服拉米夫定，并持续用至化疗结束后至少8周以上；另外历史对照组116例患者未接受预防性拉米夫定口服。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。