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Spearmint oil significantly reduced MDA in lung homogenate, and decreased the expression of Nrf2 protein in lung tissues. Conclusion: Spearmint oil has protective effect on lung injury in COPD rats, since it improves pulmonary inflammation, oxidative alteration, and enhances Nrf2 protein expression.

留兰香油对肺炎克雷伯杆菌和脂多糖引起的大鼠COPD模型的肺部炎症、肺气肿、杯状细胞增生和氧化改变有改善作用,并对肺炎克雷伯杆菌和LPS引起的肺组织Nrf2蛋白表达增强有降低作用。

Methods:Expression of PPAR-γ in 15 cases of non-cancerous lung tissues and 64 cases of lung cancer tissues was detected by using immunohistochemistry. The average A values were measured by using image analysis. The expression of PPAR-γ in lung cancer cells was detected by using RT-PCR.

方法以免疫组化的方法分别检测15例非癌肺组织和64例肺癌组织中PPAR-γ的表达,并通过图像分析测各组的平均吸光度值。

Finally the pathological change implicates the lung section bronchial tube pulmonary alveolus fills in the cleaning solution cd3 t cell obviously to be lower than does not have the lung section group which the pathological change implicates, cd4 t cell, cd4/cd8, the nk cell obviously to be lower than the opposite side lung section group which the pathological change has not implicated.

结果 病变累及的肺段支气管肺泡灌洗液中cd3t细胞明显低于没有病变累及的肺段组,cd4t细胞、cd4/cd8、nk细胞明显低于病变没有累及的对侧肺段组。

Tissue Preparation: 159 cases of paraffin sections of lung carcinomascomprised of adenocarcinoma (84 cases), squamous cell carcinoma (42 cases), smallcell lung carcinoma (10 cases), large cell carcinoma (15 cases), pleomorphic carcinoma(4 cases), and metastatic colon carcinoma (4 cases), and 86 adenocarcinomas fromsome organs other than lung, including colon (15 specimens), stomach (5 specimens),prostate (5 specimens), breast (35 specimens), uterus body (11 specimens), ovary (10specimens) and thyroid (5 specimens) were chosen from the surgical files ofYamanashi University Hospital and Kofu City Hospital.

标本来源:159例肺癌及其癌旁组织标本包括84例腺癌、42例鳞癌、10例小细胞癌、15例大细胞癌、4例多形性癌和4例肺转移性结肠癌,以及86例全身其他组织腺癌及其癌旁组织标本包括15例结肠腺癌、5例胃腺癌、5例前列腺癌、35例乳腺癌、11例子宫内膜腺癌、10例卵巢癌及5例甲状腺癌,均来自日本山梨大学附属医院和甲府市立医院外科手术标本。

ABSTRACT Antitumor Activity of Dendritic Cells Activated with gP96 Peptide Complex Department of Thoracic Surgery, Peking University People's Hospital Objectives: To investigate the expression level of gP96 in human lung cancer samples; purify gP96-polypeptide from human and mouse lung adenocarcinoma cell lines; prepare tumor vaccine by in vitro gP96-polypeptide stimulation of monocyte-derived dendritic cells and test its efficiency both in vitro and in mice models.

研究人肺癌组织热休克蛋白gP96—多肽复合物的表达水平;肺癌细胞株来源的肿瘤组织gP96—多肽复合物的提取和鉴定;外周血来源树突状细胞培养和鉴定:将gP96—多肽复合物和DC体外共同孵育制备疫苗,在体外激活T淋巴细胞的能力及在小鼠体内的抑制肿瘤生长作用的研究。

From 1 to 7 weeks PC MG could be isolated from laryngeal swabs in all the vaccinated groups and the unvaccinated,but the isolation rate was lower in the former.7 weeks PC MG could be isolated from trachea,lung and air sac in the control group,while in Group I MG was isolated only from trachea and lung.

攻毒后第7周从对照组鸡的气管、肺、气囊中均可分离到MG,而试验Ⅰ组仅在气管和肺中分离到了MG。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,"PMN-EC"相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

We hypothesized that lung injury and inflammation in ventilation-induced lung injury are related to angiotensin Ⅱ.

我们假设机械通气导致的肺伤害与肺脏的血管收缩素有关。

Results The extract of Huanglian Xiangru Decoction with different proportions of herbs could inhibit pathological changes in lung of mice caused by FM1 strain of Influenzavirus A and lower lung index, indicating anti-influenza activities in vivo with antifebrile effects on febrile rats caused by yeast, resistance to acute inflammation of auricular swelling of mice caused by paraxylene, decreasing writhing times of mice caused by glacial acetic acid, and increasing pain threshold of mice caused by hot plate.

结果 不同比例的黄连香薷饮提取物可明显抑制甲Ⅰ型流感病毒FM1株引起的小鼠肺部病变、降低肺指数,有体内抗流感病毒作用,对酵母所致发热大鼠有退热作用,对二甲苯所致小鼠耳廓肿胀有抗急性炎症的作用,有减少冰乙酸致小鼠疼痛扭体次数和提高热板致痛小鼠痛阈值的作用。

Objective:To investigate the effects of antimalarial artemether on the proliferation of human lung adenocarcinoma cell line A549 in vitro and provide experimental data for the treatment of lung cancer with artemether.

目的:研究抗疟疾药物蒿甲醚对人肺腺癌A549细胞株体外生长的影响,为蒿甲醚治疗肺癌提供实验依据。

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The shaping method of noncircular part and the tool holder's radial motion characters in noncircular turning process are discussed in detail in the thesis.

论文详细研究了非圆零件的成型方法和加工过程中刀架的径向运动规律。

I have not really liked him,I do not like his this kind of disposition.

我没有真的喜欢他,我不喜欢他的这种性格。

As we know the price of traditional product is composed of the cost and the profit of the company involving market competition, monopolizes and many other factors.

我们知道作为传统的商品,定价的模式往往是在成本的基础上增加厂商的预计利润而形成其价格,当然也要考虑到市场竞争、垄断等其他方面的因素。