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dopamine and acetylcholine inhibited the expression of iNOS in primary glia challenged by LPS in different ways.

结论多巴胺和乙酰胆碱通过不同的方式抑制LPS刺激的原代胶质细胞iNOS的表达。

Then according to the cascade of IPS and LPS, the multi-stage rearrangeable nonblocking Omega network was introduced. Moreover, the method of bipartition graph was adopted to ascertain the node state of each stage. At last, a module of the rearrangeable nonblocking Omega network, which was integrated with polarizing beam-splitter,λ/2 wave plate and perfect shuffle Plates, was constructed.

该方法通过逆混洗(Inverse Perfect Shuffle, IPS)和左混洗(Lott Perfect Shuffle, LPS)的串联,构成多级的可重排、无阻塞的Omega网络,采用二分图法依次确定各级节点开关的状态,最后通过偏振分光棱镜(Polarizing Beam Splitter, PBS)、半波片(λ/2 wave plate)和PS Plate的组合,得到可重排、无阻塞的Omega网络交换模块。

Blood samples were drawn at 30 minutes before and 0 minute, 12 hours, 24 hours, 36 hours and 48 hours after the race from 14 subjects' forearm veins. PHA and LPS were used for assessing lymphocyte proliferation; lyses of 51Cr labeled K562 target cells were used for assessing natural cytotoxicity. Results showed that the lymphocyte proliferation stimulated by PHA and LPS was decreased at least for 24 hours; the natural killer cytotoxicity is increased at 0 minute and decreased at least 48 hours after the race.

本研究以14位一般大学男生为研究对象,血液样本於14位受测者跑步前30分钟及跑步后0分、12小时、24小时、36小时与48小时於受测者前手臂静脉抽取,以PHA及LPS有丝分裂原刺激淋巴细胞,评估周边血液中淋巴细胞增殖功能;以自然杀手细胞分解51Cr标记之K562标的细胞释出51Cr之总量,评估自然杀手细胞毒杀活性。

The results of filtrating LPS under low pressure showed that metamorphosing property between LPC and polymer coils in a normal polymer solution was different.

LPS形成后改变体系盐浓度,LPC的尺寸即发生变化,说明LPC比较松散,具有良好的变形性,LPS中分散的LPC与聚合物溶液中聚合物线团的水化性能无本质差别,不是凝胶微球。

Result: Shengdi injection could depress the increasing of the amount of total white blood cells and neutrophils and inhibit the increasing of TNF-α, O-2, MPO caused by LPS, as well as relieve the pathologic change including Neutrophils infiltrating and mucous edema in tracheae after intravenous administration. While it did not show the effect on monocyte, and histological lesion of the lung tissue.

结果:生地注射液静脉给药可明显抑制LPS诱导的白细胞总数和中性粒细胞数目升高,对淋巴单核细胞数目无明显影响;明显抑制TNF-α,O-2,MPO水平升高;明显抑制LPS诱导的肺组织中性粒细胞浸润、气管黏膜水肿,对肺组织损伤无影响。

There was no big alteration in MAP in small dose of LPS-treated animas in first 3 hrs after treatment, and then, MAP was decreased slowly at 3hr time and rapidly at 4 hrs time point.

小剂量LPS(5 mg/kg)组大鼠注入LPS后3 h内MAP没有明显的变化,3 h后开始缓慢下降,4 h时明显下降,6 h接近最低水平。

Cinnamomea, antrocamphin A was purified from previous ethanol extraction using bioactivity-guided fractionation. As results, the antrocamphin A could significantly inhibit NO and PGE2 autacoids production in LPS-induced RAW 264.7 macrophage cells. Meanwhile, the mRNA and protein expression levels of iNOS and COX-2 were inhibited by antrocamphin A in a dose-dependent manner. Antrocamphin A also reduced the translocation of NF-κB induced by LPS, which was associated with the prevention of the degradation of I-κB, and subsequently decreased p65/p50 proteins level in the nucleus. This is the first report demostrating the A.

接著并以活性为导向的分离策略,从樟芝子实体乙醇抽出物中分离出具抗发炎活性成分antrocamphin A,续利用LPS诱导小鼠巨噬细胞(RAW 264.7)产生发炎的模式,解析antrocamphin A之抗发炎机制,结果证实antrocamphin A确可有效抑制一氧化氮自由基和前列腺素的生成,透过蛋白质表现分析得知,antrocamphin A之抗发炎活性是经由抑制一氧化氮生成酵素和第二型环氧酵素的mRNA表现,进而抑制了一氧化氮生成酵素、第二型环氧酵素和核转录因子-κB等酵素之表现。

The study above made experimental basis for the further study of lactoperoxidase system as natural food preservative used in the whole food industry, and provided reliable experimental data for developing compound preservative which mainly consisted of LPS in the future.

以上研究为进一步探讨LPS作为天然保鲜剂在包括冷却猪肉开发的整个食品行业中的应用奠定了实验基础,并为今后研究开发以LPS为主要成份的复合保鲜剂提供可靠的实验依据。

Lymphocytes and monocytes separated from blood and head kidney of silver carp were cultured in the medium added with LPS stimulator.

将从血液和头肾中分离的淋巴细胞和单核细胞离体培养的过程中,添加LPS刺激培养细胞,收集培养液并利用亲和层析和电泳的方法,证实了经过LPS刺激的细胞培养液中有至少有3种细胞产物出现。

Local degeneration of hepatic cell were observed, after injecting LPS, the nucleus were largened and dyed strongly. Conclusion The mouse model of alcohol liver injury was successfully established by complex alcohol liquid food and LPS, and the alcohol extract of Schisandra can reduce alcohol liver injury.

酒精联合LPS建立了小鼠酒精性肝损伤模型,适用于酒精性肝损伤防治药物的研究;五味子酒精提取物具有降低酒精性肝损伤作用。

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