查询词典 lps

Abstract］ AIM:To investigate the role of nuclear factor κB in the induction of iNOS gene by TNFα and LPS in endothelial cells and the effect of antioxidant on the induction of iNOS. METHODS:Nitrite was determined based on Griess reaction. iNOS mRNA was analyzed using Northern blot. NFκB in the cell nucleole was detected with electrophoretic mobility shift assay.RESULTS:(1)NO production and iNOS mRNA expression induced by LPS and TNFα was blocked by pyrrolidine dithiocarbamate or N-acetylcysteine.

研究表明内皮细胞激活时iNOS表达的调控主要发生在转录水平。iNOS基因的启动子区域含有多个转录因子的结合位点包括NFκB、AP-1、NF-IL6，Oct-1等［2］，而核因子κB(nuclear factor κB， NFκB)被认为在多种参与炎症反应的蛋白质因子的基因调控中担任重要角色，因而可能是内皮细胞激活的调控中一个重要转录激活因子［2，3］。

The results indicated that low-dose of Chinese nutgall water extract(2.5、5、10μg/ml)resisted the inhibitory effect of LPS to HDPCs'ALP activity significantly . From the second day , the ALP activity of HDPCs incubated with 5μg/ml Chinese nutgall water extract and LPS increased signicificantly in a time-dependent manner.

结果显示，低浓度(2.5、5、10μg/ml)五倍子水提取物能明显拮抗100μg/ml内毒素对细胞ALP活性的抑制作用，5μg/ml五倍子水提取物拮抗100μg/ml内毒素对细胞ALP活性的抑制作用第2天开始明显增加，并呈时间依赖性。

Blood sample were collected at 2,7 and 14 d post-injection to analysis the blood lymphocyte proliferation; The level of swine plague antibody of 1d pro-injection and 7, 14 d post-injection were test.

注射LPS后的第2、7和14天，采血测定其淋巴细胞转化率：注封上挑前1天、注射LPS后第7天和第14天，测定其猪瘟抗体水平。

The concentration of TNFα and IL-6 in blood obviously but only transitorily increased at 2 h and 4 h after LPS iv,and both were undetectable after 8 h of LPS iv.

血液中的炎性因子TNFα和IL-6浓度于造模后2 h和4 h显著增高，但持续时间不长，于造模后8 h恢复至正常水平。

The study had found that the cases complicating MODS and the mortality increased following the increase of concentration of sCD14. Conclusion Exdomination may be one of factors that organism released LBP and CD14 stimulated by LPS in SIRS,and LBP,CD14 can addable the effect of LPS,than cause tissue damage by multipul inflammatory factors.

结论全身炎症反应时内毒素血症可能是刺激机体合成和释放LBP、CD14的重要因素之一，而LBP、CD14又可增敏内毒素效应，进一步刺激机体产生大量炎症因子，介导组织损伤。

Microscope observations: positive staining for iNOS was observed in inflammatory cells, macrophages, kuffer cells and hepatocytes, especially at the canalicular membrane.

其中 LPS发热组3，6，gb iNOS阳性产物的整合光密度值与％阳性面积均高于正常对照组iNOS的整合光密度值和％阳性面积（P＜o.0门，且以LPS发热组6h的整合光密度值及防阳性面积为最大。

There are two elements, a CSF-box and a octamer within G-CSF promoter are essential for its promoter activity. The CSF-box is a potential NF-κB binding site, and the octamer was bound by Oct-2.

当以U0126抑制MEK1/2活性而阻断LPS所活化的MEK/ERK讯息传递路径时，发现LPS所引发的G-CSF表现量显著地下降下来。

Pathohistologic examination revealed normal glomeruli but vacuolar degeneration of tubular epithelial cells, and part of them disrupted and desquamated, and also tubular dilatation. Only mild pathological changes were seen in the intervention groups.

肾脏病理检查可见LPS组肾小球大致正常，而肾小管上皮细胞空泡变性，部分上皮细胞崩解、脱落，管腔扩张，两个UT干预组肾小管病理变化均较LPS组减轻，不同剂量组间形态差异无显著性。

Methods: Thirty-six SD rats were injected lipopolysaccharide to form ALI or saline intravenously, then were divided randomly into six groups:(1) Control group;(2) Acute lung injury group;(3) Cytochalasin D group;(4) Phalloidin group;(5) LPS+ Cytochalasin D group;(6) LPS+ Phalloidin group.

方法36只清洁级雄性SD大鼠，静脉注射内毒素复制ALI模型，随机数字法分成6个组：。

Nucleoprotein was extracted from cultured PAMs and culture supernatant of the PAMs was collected.

实验分为正常对照组o生理盐水厂 LPS刺激组o LPS10mg／L）及PMB＋LPS干预组（ X 10'UI PMB作用 0.sh再加 LPS10mg／L）。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。