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Furthermore, the liver could get the second hit by mechanical, immuneological, bio-barrier demolishment and endocrine function inbalance of the small bowel, which results in the liver function deteriorated.

肠道是应激反应的中心器官,由于肠道机械、免疫、内分泌、生物屏障的破坏等因素,肝脏受到"二次打击"的序惯性损伤。

At the same time of the fat denaturalization ,the liver lipid , blood lipid and the liver function enzymes increased .

肝脏细胞发生脂肪变性的同时肝脏脂质、血脂和肝功能酶类升高,血脂与肝脂的变化呈正相关,肝功能酶类变化也呈正相关。

Objective To clone the differentially expressed genes in liver regeneration for finally elucidating the regulatory mechanism of liver regeneration.

目的克隆肝再生中差异表达的基因,为最终阐明肝再生的调控机制奠定基础。

Methods; 45 patients with pancreatic cancer were treated with HIFU for 262 person-times.Before treating,these patients have first taken a Chinese herbal acting as strengthening the body resistance to eliminate pathogenic factors,reliving the depressed liver,sooting the liver and regulating the circulation of qi,promoting digestion and digestant for 3~4 days.In 262 person-times,74 person-times were adopted GI decompression,5~10 minutes before operation 26 person-times ware adopted simple fast,6 person-times were additionally taken airless water,and 156 person-times were additionally taken ultrasonic developer-aid for the use of GI examination.

方法; 胰腺癌患者45例,共行HIFU治疗262次,治疗前先服用扶正祛邪、疏肝理气、消食化积的中草药3~4天,采用胃肠减压者74例次,术前单纯禁食者26例次,禁食后术前5~10min加服脱气水者6例次,加服胃肠检查用超声助显剂156例次。

Measured the liver nucleic acid content of the mice liver with diphenylamine and orcinol method.

采用二苯胺法和地衣酚法测定小鼠肝脏核酸含量。

Hepatic diseases are common, about 10% of them die of acute liver failure , ALF is a sever clinical pathophysiological syndrome of metabolic, secretic and immune disarrangement caused by severe hepatocyte dysfunction and decompensation, caused by drug, toxin, severe hepatitis and cirrhosis, liver injury or/and hepatectomy.

本课题为国家"863"计划生物项目的系列研究之一肝病是多发病,其中大约10%患者死于急性肝功能衰竭(acuteliver failure,ALF),是由药物、毒物、重症肝炎或肝硬变、肝外伤或/和肝切除术后致肝细胞功能严重受损、失代偿,引起机体代谢、内分泌、免疫等功能紊乱的一种严重临床病理生理综合症。

The syndrome or symptom complex and distributive law of patients of this group on 3-7 days after the skill is:It can be split into six typings which are disharmony between Liver and Stomach + Qi deficiency, deficiency of Stomach-yin +the depressed Gallbladder with the perturbation of Phlegm, the depressed Liver with the insufficient Spleen+the coagulation of Phlegm and Dampness, deficiency-cold of the Spleen and Stomach +splinic disorder due to retention of cold Dampness, weakness of both Heart and Spleen +stagnancy of Live-qi.

本组病人胃癌根治术后3~7天证候分布规律:分为肝胃不和+气虚、胃阴亏虚+胆郁痰扰、肝郁脾虚+痰湿凝结、肝郁脾虚+气滞血瘀、脾胃虚寒+寒湿困脾、心脾两虚+肝郁型六大类型。

Histochemical, immunochemical and in situ hybridizative methods and technique of computer image analysis were used in this study to investigate the variable trends of expression and correlation of some proteins and genes interrelated with abnormal proliferation of hepatocyte during periods of hepatocarcinogenesis induced by diethylnitrosamine, and the effect of Ganfujian Granule, which is composed of drug-food double-duty herbs, taking"jian-pi-shu-gan"(invagorating spleen and soothing liver) as therapeutic principle and manufactured by our department. The purpose of the study is to screen out an applicable and effective liver cancer preventive agent of traditional Chinese medicine, to offer academic foundation for further clinic study and to spread out its application.

本课题通过组织化学、免疫组化、原位杂交等方法及计算机图像分析等技术,检测了化学致癌物二乙基亚硝胺诱导大鼠肝癌形成过程中与肝细胞异常增殖相关的部分蛋白、基因表达的动态变化和相互关系及我科研制的以"健脾疏肝"立法的药食两用中药制剂肝复健冲剂对诱发肝癌各时期上述因素异常变化的影响,旨在筛选适用、有效的中药肝癌预防制剂,并为进一步的临床试验及推广应用提供一定的理论依据。

We were initially looking for what is driving liver stem cell proliferation during chronic liver injury.

但最初我们的目的是寻找在慢性肝损伤时什么动力推动了肝脏干细胞的增殖。

Objective:To study the relationship between liver cirrhosis,liver cell dysplasia and hepatocellular carcinoma.

目的:探讨肝硬变、肝细胞不典型增生与肝细胞癌的关系。

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