查询词典 limbal

Objective To observe the therapeutic effects of limbal epithelial autograft transplantation for treatment of pterygium.

目的观察自体角膜缘上皮移植术治疗翼状胬肉的疗效。

AIM: To observe the effect of limbal corneae stem cell autograft transplantation in treatment of recurrent pterygium.

目的：观察自体角膜缘干细胞移植治疗复发性翼状胬肉的临床疗效。

Objective To investigate the effect of transplantation of limbal autograft following microsurgery for pterygium.

目的 观察各种类型翼状胬肉显微手术切除后自体角膜干细胞移植的临床疗效。

Objective To understand the effects of limbal autograft transplantation on local or whole limbal deficiencies.

目的 探讨自体角膜缘移植术在局限性或全角膜缘缺陷症治疗中的作用。

ABSTRACT］ Objective: To investigate the effect of transplantation of limbal autograft following microsurgery for pterygium.

导读：观察各种类型翼状胬肉显微手术切除后角膜干细胞移植的疗效。

Methods Limbal epithelial autograft transplantation was performed on 68 cases (76 eyes) with pterygium or its recurrent lesion.

方法采用自体角膜缘上皮移植术对68例（76只眼）初发和复发性翼状胬肉患者进行治疗，术后随访6～18个月。

The animal experiment stage: 40 rabbits underwent corneal epithelium curettement and limbal ablation to induce limbal stem cell deficiency and were randomly divided into four groups, simple amniotic membrane group, non-frozen cells group, glycerol group and dimethyl sulfoxide group(n=10 for each group). Searching for the activity of frozen and non-frozen cells more completely by transplanting subculturing cells and observing the accomplishment of cells function.

动物实验阶段：将40只角膜缘干细胞损伤的模型兔随机分成单纯羊膜组、未冷冻细胞组、DMSO保存细胞组和甘油保存细胞组，每组10只，用传代培养2周后的角膜缘上皮细胞作移植实验，观察细胞体外功能完成情况来进一步比较深低温保存前后角膜缘上皮细胞的活性。

However, the resource of the grafts is often limited.Limbal heterograft and transplantation with the in vitro limbal stem cells are expected to be new managements for this disorder.

然而，由于自体取材在很多情况下受限，同种异体角膜缘上皮移植和以体外培养的角膜缘干细胞移植是最新的研究目标。

The limbal stem cells could be successfully cultured in vitro and own the same characteristics as normal limbal stem cells have.

应用组织培养方法获得的原代培养细胞具有与正常角膜缘干细胞相一致的生物学特性。

The results are unsure for experimental use;The rabbit's corneas that were removed with upper-half of corneal limbal epithelium lamella and erased the center corneal epitheliums were transparent with intact corneal epithelium;In the approach,the corneal and limbal epitheliums were burned with a cotton swab socked in 1 mol/L NaOH,there were 4 rabbits' corneal stroma happened perforation or ulcer and symblepharon,and the other one presented corneal epithelium phenotype.This is an applicable method to create the pathological model of corneal limbal stem cell total deficiency.

结果表明，处理后4周，全周角膜缘上皮板层手术切除，中央角膜上皮层用1 mol/L NaOH擦除的5只试验家兔角膜表面全部血管化、结膜化，未发生睑球粘连，角膜基质胶原纤维完整未见溃疡、穿孔等病变，细胞印迹学检查为结膜表型，可作为实验性角膜缘干细胞移植的病理模型；全周角膜缘上皮板层手术切除，中央角膜上皮用生理盐水擦除的5只试验家兔，有2只为结膜表型，另3只为角膜表型，观察期内结果不稳定；半周角膜缘上皮板层手术切除，中央角膜上皮层用生理盐水擦除的5只试验家兔，角膜表面透明，全部为角膜表型；直接用1 mol/L NaOH擦除角膜缘和中央角膜上皮的试验家兔，有4只角膜基质胶原纤维断裂、溶解，并伴有严重的溃疡、穿孔、睑球粘连等病变，不能用于移植试验，另1只角膜表面透明，未见结膜和新生血管长入，细胞印迹学检查为角膜表型。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。