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Our results suggested that Onconase could increase its specificity via conjugating with ligands. Our studies also give the way to develop the new antitumor drugs.

我们的研究证明了构建基于Onconase的特异性抗肿瘤蛋白的可行性，为以后开发Onconase的特异性抗肿瘤药物打下了基础。

In this study, several systems of proteins in complex with halogenated ligands have been investigated by using a two-layer QM/MM ONIOM methodology.

因此，系统地研究生物体系中的卤键，特别是蛋白质与卤代配体间可能的卤键，阐明卤键在配体识别过程中的作用，对药物发现与设计有重要意义。

For comp ound 7, the cage is consisted by six MoO〓 and four PO〓. The six MoO〓 octahedrons have consisted to the loop structure, the there PO〓 tetra hedron become triangle and the other one lies the centre. The one oxygen of two MoO〓 octahedron is coordinated to Mn atom which linked the other cage like this cag e and this Mn have six ligands.

在化合物7中，每一个笼由6个MoO〓八面体和4个PO〓四面体构成，6个MoO〓八面体构成环，四个PO〓四面体形成一个三角形在其上面，4个P和6个Mo具有C〓的对称性，每二个MoO〓八面体提供一个O原子与Mn原子配位，这个Mn原子再与相同的这样的笼相连，形成一个中间细两端粗的形状，这个Mn原子是6配位的，每一个这样的笼再通过一个Mn原子连接起来，形成二维的网状结构，而这个Mn原子是五配位的。

Therefore, we have tunned the ratio of copper to ligands and compounds 18 and 19, 20 and 21 are obtained.

因此，我们对金属-配体的摩尔比进行调控，得到化合物18和19，20和21。

Therefore, we have tunned the ratio of copper to ligands and compounds 18 and 19, 20 and 21 are obtained.

当采用配体1，4-双三氮唑时，得到了两个同构的化合物22和23，它们展示了二重穿插的3D框架。

The competitive binding of two ligands, ibuprofen and salicylic acid, to human serum albumin was studied using NMR chemical shift and relaxation measurments.

第三章 3。随着蛋白质与配体结合研究的深入，开展了多个配体与单个蛋白相结合的研究。

The effect of the concentration, pH of several ligands such as acetate, oxalate, tartrate and phosphate solution and their orders added on the adsorption and activity of BSA and acid phosphatase on yellow brown soil, latosol, kaolinite, goethite and -MnO2 was first systematically studied by using batch and FTIR methods after analyzed and studied the relative literature that reported in the world.

论文在分析总结了国内外有关研究的基础上，用批量法和傅立叶变换红外光谱法首次系统地研究了乙酸、草酸、酒石酸和磷酸几种配体的浓度、pH及加入顺序对牛血清白蛋白、酸性磷酸酶在黄棕壤、砖红壤、高岭石、针铁矿和二氧化锰表面的吸附行为及活性的影响，探讨了这些配体对蛋白吸附机理及二级结构的影响。

Synthesis and structural characterization of novel cycioplatinated complexes with 2-aryl imidazolines 2-arylimidazoline ligands 2a-2d were synthesized from benzoyl chloride or p-methoxybenzoyl chloride with aminoethanol or valinol and 2e was synthesized from 2-phenylimidazoline.

新型2-芳基咪唑啉环铂化合物的合成与结构表征以苯甲酰氯或4-甲氧基苯甲酰氯和氨基醇(2-氨基乙醇或外消旋的缬氨基醇)为原料，合成了四种2-芳基咪唑啉配体2a-2d，以2-苯基咪唑啉为原料合成了配体2e，其中2d为新化合物。

Meanwhile, more ligands were tethered onto the comb-like PEG modified surface with a great amount of reactive end groups, which increased cell proliferation. The glycocalyx mimicking surface designed with comb-shaped PEG end-tethered by RGD peptide was proved to present non-specific resistance and excellent cyto-compatibility simultaneously.

此外， CPEG比LPEG具有更多的活性反应基团，用PEG末端活性的醛基固定整合素配体多肽片段RGD，可有效地诱导材料表面的内皮细胞化，改善材料的细胞相容性。

The catalytic activities of other rare earth metal salts with different ligands were tested.

考察了带有不同配体的稀土金属催化剂对反应的影响。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了