查询词典 ligands

By following the "self-assisted molecular editing" protocol first established in our labs,a number of Aphos ligands were efficiently prepared from a single starting material and they were screened for catalytic efficacy, leading to the discovery of the best-performing Aphos appended with a 3-nitrophenyl group at the C4 position.Combination of this Aphos with Pd_2 offers a precatalyst for successful cross-coupling of unactivated aryl chlorides with aryl boronic acids at room temperature.The reactions took place under mild basic conditions to produce the products in high yields.

通过我们首次提出的&自助分子剪裁&的概念从单一起始物快速合成和筛选了一系列膦配体，并发现C4位含3-硝基苯基的的膦配体和醋酸钯联用可以在室温下顺利地催化不活泼氯代芳烃和芳基硼酸的偶联反应，反应条件温和且产物收率很高。

RIG-I detects RNA ligands derived from uncapped viral transcripts and initiates the IFN response.

野生鸟类感染A型流感的时候通常并不生病，尽管鸡和其他驯化的禽类可能死亡。

RIG-I detects RNA ligands derived from uncapped viral transcripts and initiates the IFN response.

他们提出这种蛋白有可能转移到鸡的细胞中，从而产生类似的免疫应答。

The relationship between the type of ligands, composition of the complexes, structure of the complexes with the properties of lowering blood sugar was studied and the corresponding law was concluded, the research will provide certain theoretical basis for the deep research of amino-acid vanadyl complexes with anti-diabetic properties.

研究配体的类型、配合物的组成、配合物的结构与降低血糖功能之间的关系并总结出相应的规律，为具有抗糖尿病功能氨基酸氧钒配合物的深入研究提供一定理论基础。

It is a original work in the world that using these ligands to coordinate with vanadyl cation to form complexes and the study of the structures along with the anti-diabetic properties, thus provide us opportunity to obtain vanadium drug with the properties of lowering blood sugar significantly and low toxicity, the research will benefit the large number of diabeticpatients, the economic and social benefit will be obvious.

上述配体与氧钒离子形成配合物及结构和抗糖尿病功能的研究在世界上属首创工作，使我们有望制备出具有显著降血糖功能且低毒性的钒类药物，为广大糖尿病患者带来福音，产生明显的经济效益和社会效益。

Four amino-acid ligands(glycine, serine, aspartic acid, phenylalanine) was selected to coordinate with vanadyl cation to form amino-acid vanadyl complexes.

选择甘氨酸、丝氨酸、天冬氨酸和苯丙氨酸四种氨基酸与氧钒离子配位形成氨基酸氧钒配合物。

According to Johnson's Rule and IR spectra, their possible structures are suggested. The bonding parameters of those complexes are calculated by ESR parameters. And the crystal field parameters are calculated by using electronic spectral data. It can be seen that the vanadyl complexes in the solution are ionic complexes and that the α〓 values of those complexes decrease following the increasing of the N donor replacing the O donor of water on the equatorial plane in those complexes. This means that the covalent bonding between vanadium and ligand increases as Ser, Phen or Bipy replace water ligands. The results show the competitive coordinate law that the coordination reactivity of Phen and Bipy is much stronger than that of Ser. The simulation program of ESR is compiled by the theory of ESR in the present work.

测定了VO-丝氨酸二元体系、VO-丝氨酸-邻菲咯啉三元体系和VO-丝氨酸联吡啶三元体系在不同酸度下（pH=1.0～14.0）的乙二醇／水（V／V=1：1）溶液低温ESR谱，发现不同pH下，溶液中具有不同组成的配合物，根据不同pH下ESR谱的变化，利用Johnson的加合规则并结合红外光谱，推测了它们在溶液中的可能结构；利用波谱参数计算了配合物键参数；利用电子光谱数据计算了配合物的晶体场参数，讨沦了它们的成配特性，结果表明：VO配合物属离子型配合物，随取代水分子的配体（Ser、Phen或Bipy）数目增加，键参数减小，配合物共价性增强，同时得出这些体系中，生物配体竞争配位规律：Phen和Bipy与VO的配位能力比Ser强。

Epidermal growth factor receptor and its ligands (EGF and TGFα) are over-expressed in a variety of tumors. Immunization EGF-carrier protein inhibits tumor growth through abrogating binding of EGF to EGFR.

表皮生长因子受体(Epidermal growth factor receptor ， EGFR)及其配体在多种肿瘤细胞中高表达，免疫注射表皮生长因子(Epidermal growth factor，EGF)-载体蛋白所产生的抗体能够干扰EGFR与EGF的相互作用，进而抑制肿瘤生长。

Therefore, adsorbed proteins would retain the ability to bind to their respective ligands.

因此，吸附的蛋白将保持结合于其相应配体的能力。

The design and synthesis of effective chiral ligands play important roles in transition-metal catalyzed asymmetric reactions.

在金属介入的不对称催化反应中，手性配体的设计合成扮演着极重要的角色。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。