查询词典 ligand

It is possible to preparing neutralizing MAb which target to active region of Stx2 by synthetical B cell epitope peptides. At present, the crystal structure of the compound of Stx2 and its ligand adenines has been resolved, and the active site of Stx2 is definite, which is the seventy-seventh amino acids, Ganimalon, of Stx2 A1 fragment.

Stx2通过B亚基与受体Gb3结合后，进入细胞，在弗林蛋白酶(一种钙敏感的丝氨酸蛋白酶)作用下A亚基被裂解为A1和A2两个片段，A1片断经内质网进入细胞质暴露毒性活性位点―A1片段发挥N-糖苷酶活性，导致真核细胞蛋白质合成的终止，最终导致细胞的死亡。

BACKGROUND: Studies demonstrated that incisor continuously growing is due to lack of epithelial root sheath formation. However, researches regarding whether receptor activator of nuclear factor κB ligand and osteoclast has correlation with continue root development is poorly understood.

背景：研究表明小鼠不断生长的切牙是由于切牙仅有颈环而无上皮根鞘的形成，但是破骨细胞分化因子核因子κB受体活化剂配体和破骨细胞与不断生长的牙根发育是否相关，目前研究较少。

Since the contribution of the spin-orbital coupling interaction of the ligand to optical and electron paramagnetic resonance spectra can not be neglected, the optical and EPR spectra g factors g‖、g⊥ and hyperfine structure constant A‖、A⊥ of LiHSO4:VO2+ crystal are calculated from the high-order perturbation formulas on the basis of double-spin-orbital coupling model and crystal-field theory for 3d1 ion in tetragonal symmetry.

考虑到配体离子的自旋－轨道耦合作用对光谱和电子顺磁共振谱的贡献不可忽略，采用3d1离子在四角对称下基于双自旋－轨道耦合模型的高阶微扰公式和晶场理论公式，理论计算了LiHSO4：VO2+晶体的光谱和电子顺磁共振参量g因子g‖、g⊥和超精细结构常数A‖、A⊥。

When the reaction was finished, the ligand was extracted with CH2Cl2 and precipitated upon addition of diethyl ether followed by filtration.

2配体2在丙酮/水体系中催化/又种烯烃的AD反应，非链端烯烃的立体选择性(80一99%ee)明显优于链端烯烃(51一62%ee)。

Recently Kuang reported a recoverable and reusable free ligand that could be recovered by precipitation upon addition a little of diethyl ether.

本文所说的小分子并不是通常人们所说的NO、CO和CO_2等小分子，而是相对于大分子而言，这些手性配体是小分子(FW＜1000)。

Oxalic acid loading substantially stimulated soil P release from A1 horizon, showing a linear relationship; but its effect on B horizon soil was relatively negligible, especially at low oxalic acid concentrations mmol L^(-1. Oxalate solutions 0.5~20.0 mmol L^(-1 oxalic acid adjusted to pH 5.16 with 10.0 mmol L^(-1) NaOH had a much higher (1.51~2.98 times) soil-P-release effect than oxalic acid solution the same in oxalate concentration. Therefore, the mechanism of oxalic acid/oxalate triggering release of soil phosphorus is assumed to be dominated by ligand-exchange or complexing reactions of oxalate anionC2O(superscript 2- subscript 4 but not simply acid-dissolving effect. The effect of oxalate anion on soil phosphorus release was found to be somewhat cumulative, i.e. the amount of P released was primarily controlled by the cumulative oxalate loading rate, relatively independent of the manner of oxalate addition (one-time or sequential).

结果表明，草酸能显著促进暗棕壤A层磷的释放，土壤磷溶出量随草酸溶液浓度升高而线性增加；但对B层土壤磷的释放效应相对较弱，草酸浓度低於5mmolL^(-1)时B层磷的释放不明显。pH5.16草酸钠溶液比相同浓度的草酸溶液具有更高的解磷效率，在设置二者浓度为0.5~20.0mmolL^(-1)时，前者的解磷量是后者的1.51~2.98倍，推断草酸盐溶液或凋落物淋洗液中草酸类物质促进暗棕壤磷释放的主要机理在於草酸阴离子C2O(上标 2-下标 4配位反应。

As support, Agarose can benot only used in normal condition, but also in denaturalization (for example, 6 mol/Lhydrochloric acid carbamidine or 8 mol/L urea). Herein, the preparation of IMACmatrixes were conducted using agarose as support, carboxymethylated aspartate as chelating ligand and Co~(2+) and Ni~(2+) as chelating center ions.

本实验用琼脂糖作为基质，选用四配位，与金属离子有较强作用力的羧甲基天冬氨酸为配基，以Co~(2+)、Ni~(2+)作为螯合金属离子，合成了一系列金属螯合亲和色谱填料，并对其蛋白质分离性能进行了研究。

This is the first example of a ligand-modulated ARR characterized.

这是首例关于非典型应答调控蛋白结合小分子配体的报道。

OBJECTIVE: Our objective was to evaluate the short-term efficacy of the novel multireceptor ligand somatostatin analog pasireotide in patients with de novo, persistent, or recurrent Cushing's disease.

目的：本研究的目的是评价新型多受体配体生长抑素类似物pasireotide治疗新发的、长期的或复发性库欣病患者的短期疗效。

Furthermore, the effects of ligands, metal and reaction time on the reaction were also researched, and the process of new ligand-metal catalysis for Diels-Alder reaction was also analyzed according to Evans" square planar mode and Corey"s tetrahedral manner.

我们对影响配体对映选择性能的各种因素，如配体结构、金属离子、反应时间等进行了研究，而且根据Evans的平面四方形模式与Corey的四面体过渡态理论为新配体—金属配合物催化的该反应提出了可能的反应机理，并对产物的优势构型作了理论分析。

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了