查询词典 leukemic

Incontrast, berbamine had slight effect on normal bone marrow cells and its IC〓 value was 103.650± 10.257μg/ml which was 17.5-27.5 times higher than those of leukemic cells.

上述结果提示，小檗胺具有较广谱的抗白血病细胞的作用，白血病细胞对小檗胺的敏感性明显地高于正常骨髓单个核细胞。

Based on the above findings, it could be concluded that:(1) berbamine could obviously inhibit the cell proliferation and induce apoptosis in four different kinds of leukemic cell lines (including K〓, Jurkat, NB〓, HL〓 cells) in a time-and-concentration-dependent manner in vitro.

综上所述，我们认为：(1)钙调素拮抗剂小檗胺在体外除对HL〓细胞外，还对其它3种不同类型的白血病细胞株(K〓、Jurkat、NB〓)细胞具有明显的增殖抑制作用及明确的诱导凋亡作用，并呈时间-浓度依赖关系，诱导细胞凋亡可能是其抑制白血病细胞增殖的主要方式之一。

Results: The risk factors for leukemic transformation and early death were bone ache, Hb＜30 g/L, dysplastic peripheral blood polymorphs, RAEB,RAEB-T of MDS subtype, blast of bone marrow and peripheral blood＞5%,with advancing myelofibrosis, ALIP,-7/7q-+8 and cytogenetic abnormalities at more than two chromosomes.

结果：剧烈骨痛、Hb＜30 g/L、外周血粒系发育异常、RAEB、RAEB-T MDS亚型、骨髓或外周血原始细胞＞5%、伴发MF和ALIP、-7/7q-，+8染色体异常或复合染色体异常为MDS预后不良因素。

Naujokat C, Sezer O, Zinke H, et al. Proteasome inhibitors induce caspase-dependent apoptosis and accumulation of p21WAF1/Cip1 in human immature leukemic cells.

低剂量蛋白酶体抑制剂MG132导致EPCs数量减少和功能受损的确切机制尚不明确，可能与下列因素有关：1。

Atorvastatin can inhibit leukemic cell proliferation. HMG-CoA reductases inhibitor has possible adjunctive therapy effect on AL.

阿托伐他汀具有抑制白血病细胞增殖作用，HMG-CoA还原酶抑制剂可能有辅助治疗AL的作用。

Methods:The imitative chronic myeloid leukemic bone marrow in remissionhad been cultured in liquid mediam with IL-2 and IFN-γ for 1-6days,and the puring effect wasdetermined bydetection of the bcr/ab1 mRNA.

将IL-2、IFN-γ与模拟慢性粒细胞白血病缓解期的骨髓在培养体系中分别培养 1-6d，通过RT-PCR方法来检测缓解期骨髓中bcr/abl mRNA消失情况。

The major clinical manifestation was lymph node enlargement found in all patients. Skin involvement and osteolysis were not frequent. The characteristic finding was leukemic cells with highly indented or lobulated flower-like nuclei in peripheral blood and bone marrow. ATL cells were CD2,CD3,CD4,CD25 positive and CD8 negative. No specific chromosome abnormality or HLA type was found. Seven of 8 patients examined had HTLV-Ⅰ antibody. The HTLV-Ⅰ provirus genome sequence integrated into host cell DNA was amplified by PCR and confirmed by liquid hybridization. All of these results showed that HTLV-Ⅰ was also the etiological agent of ATL in China. One of the 9 cases of ATL was classified as lymphoma type, one as chronic-type, and the rest as acute type.

结果和结论确诊9例ATL，其临床特征主要为淋巴结肿大，皮损及溶骨改变少见，外周血及骨髓出现典型的花瓣状核淋巴细胞，胞体大，核畸形，免疫表型为CD-1、CD+2、CD3+、CD4+、CD-8，还表达CD25等激活标记，染色体核型及HLA分型未发现有规律性的变化。8例ATL中有7例血清HTLV-Ⅰ抗体阳性，应用PCR及液相杂交法可检出整合到宿主细胞DNA中的HTLV-Ⅰ病毒序列，表明在我国HTLV-Ⅰ也是ATL的病因。9例中1例为淋巴瘤型，1例为慢性型，7例为急性型ATL，治疗效果及预后均不良。

But umbilical blood can be an incredibly effective tool in treating leukemic patients.

但是脐带血对于治疗白血病很有效果

Besides,we alsoinvestigate the machanism of the reversal of MDR with Lipophilic drug andCytokines in leukemic cells.

此外，本文还探讨了亲脂类药物和细胞因子逆转白血病细胞MDR的机理。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。