查询词典 leukemia

Our results indicate that 1 NSC606985, at nanomolar level, can effectively induce apoptosis in AML cells NB4 and U937 and significantly inhibit the proliferation without cell death in breakpoint cluster region–Abelson murine leukemia kinase-carrying leukemic K562 cells; 2 At such low concentrations, this agent also significantly inhibits the clonogenic activity of hematopoietic progenitors from patients with AML; 3 For apoptosis induction, NSC606985 rapidly induces the proteolytic activation of protein kinase Cδ with loss of mitochondrial transmembrane potential and caspase-3 activation; 4 Co-treatment with rottlerin, a PKCδ-specific inhibitor, completely blocks NSC606985-induced mitochondrial m loss and caspase-3 activation, while the

结果显示：(1)纳摩尔浓度的NSC606985即可有效诱导AML细胞系NB4和U937细胞凋亡并显著抑制含有bcr-abl融合蛋白激酶的K562细胞的增殖；(2)低浓度的NSC606985也显著抑制来自AML病人骨髓的新鲜白血病细胞的克隆形成能力；(3)除了迅速诱导线粒体跨膜电位的崩塌及Caspase-3的活化外，NSC60698也导致蛋白激酶Cδ的水解激活；(4)PKCδ特异的抑制剂rottlerin能够完全抑制NSC606985诱导的线粒体跨膜电位的崩塌和Caspase-3的活化，而Caspase-3特异的抑制剂z-DEVD-fmk仅能部分削弱PKCδ的活化及细胞的凋亡；(5)以移植PML-RARα转基因小鼠产生的白血病细胞建立的模型研究了该化合物对白血病可能的治疗作用。

It was recently reported in Japan that effective component of the extract of Rubia Cordifolia L has obvious inhibition for leukemia, cancer of colon and carcinoma of the lung in mice, its curative effects equaled or exceeded to the catharanthine, mitomycin and adriacin and had less virulence for normal cells.

近来日本学者系川秀治等研究发现茜草提取物中的有效成分环己肽类化合物对小鼠的白血病、腹水癌、大肠癌、肺癌均有明显的抑制作用，其疗效等于或优于长春碱，丝裂霉素、阿霉素，并且对正常细胞的毒性低。

The levels of serum SAPO 1/Fas in acute leukemia patients are significantly related to the chemotherapeutic efficiency.

APO- 1 /Fas与其配体是已认识到的一对诱导细胞凋亡的膜蛋白因子，它们之间构成一条独特的细

This method also helps to subclassify cell types, which may, in turn, help the physician to decide on the best treatment to apply in that type of leukemia or lymphoma.

种方法也能够帮助区分细胞亚型，可帮助内科医师制定最佳的治疗方案用于不同类型的白血病或淋巴瘤。

This method also helps to subclassify cell types, which may, in turn, help the physician to decide on the best treatment to apply in that type of leukemia or lymphoma.

这种方法同样能够帮助区分细胞亚型，随后就能进一步帮助内科医师制定最佳的治疗方案。

Normal lymphocytes may be distinguished from leukemic lymphocytes. This method also helps to subclassify cell types, which may, in turn, help the physician to decide on the best treatment to apply in that type of leukemia or lymphoma.

这种方法也能够用以区分细胞亚型，可帮助内科医师针对不同类型的白血病或淋巴瘤制定最佳的治疗方案。

Normal lymphocytes may be distinguished from leukemic lymphocytes. This method also helps to subclassify cell types, which may, in turn, help the physician to decide on the best treatment to apply in that type of leukemia or lymphoma.

这种方法同样能够帮助区分细胞亚型，随后就能进一步帮助内科医师制定最佳的治疗方案。

In conclusion , ERK and telomerase serve a function to some extent in drug resistance of leukemia and ovariancarcinoma cells. The inhibition of ERK signal transduction pathways led to reduction of phosphorylated ERK1 and ERK2protein expression level , and successionally down2regulated the telomerase activity.

通过阻抑ERK通路，降低磷酸化ERK1/ 2蛋白表达水平，进而下调端粒酶活性，可以达到增强白血病和卵巢癌耐药细胞对HRT 或DDP 敏感性的目的。

Patterson and colleague Sylvian Bauer injected a natural protein from the body -- leukemia inhibitory factor, or LIF -- into a part of the brain of adult mice where stem cells reside.

帕特森和他的同事西尔文。鲍尔将从骨髓基质细胞白血病抑制因子中提取出来的天然蛋白质注入到成年鼠大脑中干细胞集中的部位。

When HIV-1 in culture medium was exposed to a range of concentrations of urokinase, a dose-dependent inhibition of infectivity was observed in a variety of lymphoma and leukemia cell lines including MT4, CEM, H9, and peripheral blood mononuclear cells using assays for reverse transcriptase, P24 antigen and syncytia formation.

通过检测逆转录酶活力，P24抗原的表达和合胞体形成情况发现尿激酶可以抑制人体免疫缺损病毒对多种淋巴瘤和白血病细胞系，如MT4、CEM、H9和外周血单核细胞的侵染能力，并且这种抑制与尿激酶浓度呈剂量依赖关系。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。