查询词典 leukemia

Objective: To investigate the antitumor effects of Quercetin in P388 leukemia mice.

目的：研究槲皮素抗小鼠P388白血病的作用。

A human promyelocytic leukemia cell mutant (HL-60-AR) with deficiency in HGPRT and resistance to 8-AG was established by treat〓nt of the HL-60 cells with MNNG and prescreened in 0.3% agar RPMI-1640 semisolid medium containing 8-AG. The mutant cells show the following characteristics:(1) resistant to cytotoxic action of 8-AG and growing vigorously in medium containing 20ug/ml 8-AG;(2) capable of forming 〓〓 colonies in soft agar medium in the presenee of 8-AG:(3) highly sensitive to HAT selective medium and fail to growing in HAT medium of form colonies in soft agar medium containing HAT;(4) completely deficinet in HGPRT activity; and (5) no radioactive silver grains over the mutant cells due to the absence of -hypoxanthine incorporation showed by radioautography.

一、用MNNG诱变和8-AG进行抗性筛选，成功地建立了一株抗高浓度8-AG和完全缺失HGPRT活性的人早幼粒白血病细胞突变株(HL-60-AR)，该细胞能抵抗8-AG的毒性作用，对HAT选择培养基十分敏感，检测不到HGHRT活性，不能参入〓H一次黄嘌呤。

Objectives To investigate ras gene expression in childhood acute leukemia and its significance in the treatment and prognosis assessment.

目的 ras基因在儿童急性白血病中的表达及其与治疗和预后的相关性分析。

Objective: To investigate the effect of tanshinone ⅡA on HL-60 and K562 cells apoptosis,and to assay the inhibition of the telome rase activities in the leukemia cell apoptosis induced by Tanshinone.

中文摘要：目的观察丹参酮ⅡA对HL60，K562细胞端粒酶活性的抑制作用和对凋亡相关基因的影响，探讨丹参酮ⅡA对造血细胞的作用机理。

Objective To investigate the apoptosis of leukemia cells induced by realgar,and illustrate the possible molecular mechanisms.

目的 检测雄黄诱导白血病细胞凋亡能力，探讨分子机制。

Objective: To acquire a deep understanding of the possible mechanisms of realgar in the treatment of acute promyelocytic leukemia.

中文摘要：目的：深入了解雄黄治疗急性早幼粒细胞白血病的机理。

This suggests that these genes may be associated with the affection of realgar on leukemia cell.

细胞信号传递蛋白类Z22533和其它类NM_007057表达上调，这些基因可能与雄黄诱导的凋亡和分化过程有关。

Results It found that apoptosis was induced in leukemia cells and bcl-2 expression down-regulated by realgar.

结果 雄黄可诱导白血病细胞发生典型的凋亡，同时雄黄可使白血病细胞bcl-2蛋白表达呈时间依赖性下降。

Down-regulation of bcl-2 expression appears to play an important role in apoptosis of the differentiated leukemia cells induced by realgar.

雄黄通过影响白血病细胞bcl-2蛋白的表达，从而导致白血病细胞发生凋亡，这是其治疗白血病的重要分子机制。

The one of most interesting issues is how leukemia cells with MLL rearrangement acquire a unique feature of TRAIL-resistance.

非常有意思的问题之一是有MLL重排的白血病细胞怎样获得抵抗TRAIL的唯一特征。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。