查询词典 leukemia leukaemia

Over the past year, the group evaluated the seven-year follow-up results of therapeutic effects of all-trans retinoic acid and arsenic trioxide (As2O3) combined treatment in newly diagnosed acute promyelocytic leukemia. We also studied the mechanism of therapeutic effects of Imatinib and As4S4 combined treatment in CML cell line and animal model. These two papers were published on PNAS.

过去的一年中，本课题组总结完成了全反式维甲酸和三氧化二砷联合治疗初发急性早幼粒细胞白血病的七年临床随访资料的疗效评估；在慢性粒细胞性白血病，完成了应用As4S4和STI571联合治疗作用的细胞、分子和整体动物水平的机制研究，这两部分工作均已发表于PNAS。

Recently, the arsenic trioxide was found to be an effective drug for leukemia.

最近的研究发现三氧化二砷对於白血病的治疗颇具疗效。

To investigate the mechanism of Arsenic Trioxide treatment to Leukemia.

目的 探讨三氧化二砷(As2O3)治疗白血病的作用机制。

In tomorrow's program, we will introduce the story of leukemia treated with arsenic.

那么在明天的节目时间里我们会向大家介绍砒霜治疗白血病的故事。

Arsenical compounds can inhibit cell growth of leukemia cell at different intensity; this may be correlated with the valency of arsenic and molecular structure of arsenical compounds.

4不同砷剂对细胞作用强弱可能与其结构价态有关。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

OBJECTIVE: To study the cellular activity of asparagine synthetase in different types of childhood acute lymphoblastic leukemia.

目的：不同类型急性淋巴细胞性白血病对左旋门冬酰胺酶敏感度不完全相同，由于LAsp活性水平与细胞内门冬酰胺合成酶活性负相关，因此研究不同类型ALL患儿白血病细胞内门冬酰胺合成酶活性水平分布情况，有助于临床治疗中合理使用LAsp。

BACKGROUND: Invasive aspergillosis is a leading cause of mortality in patients with acute leukemia.

背景：侵袭性曲霉菌病是导致急性白血病患者死亡的重要原因。

In the present study, the mechanisms of how EGCG enhanced ATO cytotoxicity in leukemia cells were investigated.

结果显示EGCG和三氧化二砷并用可以显著地诱导白血病细胞中过氧化氢和细胞凋亡的发生。

C. gigantea is a high biomass, fast growing perennial shrub growing as a weed in the Hainan province of China. It was used as a traditional folk medicine for the treatment of cough, leprosy, and asthma by the people of Li nationality, who are autochthon of Hainan island of China. In our screening for bioactive agents from tropical medicinal plants, the ethanol extract of the roots of C. gigantea showed cytotoxic activity towards human chronic myelogenous leukemia (K562) and human gastric cancer (SGC-7901) cell lines in vitro by MTT method with IC50 values of 9.7 μg/mL and 6.7 μg/mL, respectively.

为了开发热带药用植物资源，从中寻找具有药用价值的生物活性成分，本文采用MTT法对牛角瓜乙醇提取物进行体外活性筛选，结果表明其对K562 及SGC-7901 具有细胞毒活性，IC50值分别为9.7 μg/mL 和 6.7 μg/mL。

You can snipe the second and third union leaders from this position.

您可以鹬第二和第三工会领袖从这一立场出发。

Aiming at the currently shortage of XML streams quality detecting, this paper proposes a new forecasting method of XML streams quality by least squares support vector machines, which is used the method of XML keys' vector matrix as windows, and vector product wavelet transform to multilevel decompose and refactor the XML streams series, that can fulfill real-time checking demand of XML quality, and ensure constraint, consist- ency and integrality. For even more adapting net load, it proposes a control strategy by weight and adaptive adjustment to ensure XML streams quality.

针对当前XML数据流质量检测存在的不足，提出构建XML键的矢量矩阵作为窗口，利用矢量积小波变换多级分解与重构XML数据流，再结合最小二乘支持向量机对XML数据流质量进行预测的一种方法，满足XML数据流质量重构时实时检测的要求，保证XML数据的约束性、一致性与完整性；为了更好的适应网络负载，采取加权与自适应窗口调整等调度策略充分保证XML数据流的质量检测。