查询词典 leucopenia

No one died or discontinued therapy for adverse effects, and 4 out of 67 (5.97%) had grade 3 or 4 thrombocytopenia and/or leucopenia in the STI571 group.

甲磺酸伊马替尼组治疗期间没有患者因药物副作用而停药、死亡，4例（5.97%）发生Ⅲ/Ⅳ级白细胞和/或血小板减少。

Results: The effects of anti-rejection Among ALG-P and ATG are similar, but the incidence of leucopenia de scend and pulmonary infection were higher in those taking ATG. Either taking ALG-P and ATG. the incidence of pulmonary infection in treatment was higher than in prevention.

结果：ALG-P与进口ATG相比，抗排异效果是一致的，而白细胞下降和肺部感染情况与进口药相比，明显降低；预防性和治疗性使用该类药，肺部感染发生率是不同的，治疗性使用者的肺部感染发生率较高。

Results Two cases were pulmonary tuberculosis combined aspergillus infection;one case was NK cell precursor acute leukemia and aspergillus infection;one case pernicious leucopenia and monilia infection;one case sjogren syndrome or diabetes both combined with candida albicans infection.CT basic manifestations included effusion or nodules or cavities or tumour.

结果 2例肺结核并曲霉菌感染，1例恶性白细胞细胞减少并念珠菌感染，1例急性NK细胞白血病并曲霉菌感染，干燥综合征及糖尿病各1例并白色念珠菌感染，CT基本表现为渗出、结节、空洞、肿块病灶。

Results:The main clinical features including fever ( 86.7%), lymphnode enlargement( 66.7%), weight loss(40.0%), fungal infection (40.0%), leucopenia ( 53.3%), normocytic and normochromatic anemia(80.0%), thrombocytopenia(40.0%).

结果 ：15例患者中发热 13例( 86 。7%)，淋巴结肿大 10例( 6 6 。7%)，消瘦 6例( 4 0 。0 %)，真菌感染 6例( 4 0 。0 %)，白细胞减少 8例( 5 3.3%)，贫血 12例( 80 。0 %)，为正常细胞正常色素性贫血，血小板减少 6例( 4 0 。0 %)，骨髓有核细胞增生、浆细胞增多及病态造血，免疫学检查主要为细胞免疫缺陷。

Topotecan is an effective agent for SCLC when used as monotherapy or in combined treatment, but myelosuppression such as leucopenia and thrombopenia was relatively severe. Although it has been recommended as a second-line agent for recurrence of sensitive SCLC, more clinical trials are needed to define its role in first-line treatment.

拓扑替康治疗小细胞肺癌有确切临床疗效，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，但具有相对高的致白细胞和血小板下降的骨髓毒性，已被认为是治疗化疗敏感的小细胞肺癌患者复发的二线推荐药物，但是作为一线用药仍然需要更多的实践来证实。

Conclutions Topotecan is an effective remedy for treatment of small cell lung cancer, both single topotecan and combined regimen has the same effect as the traditional first-line regimen, though myelo-suppression such as leucopenia and thrombopenia is more sever, the adverse effect is tolerated. Though it has been recommended as second-line agent for chemo-therapy sensitive small cell lung cancer, there needs more clinical studies to verify its role in first-line.

结论拓扑替康是在小细胞肺癌的治疗中有确切临床疗效的药物，无论是单药还是与其他药物的联合用药均具有与当前一线经典方案相当的疗效，虽具有相对高的致白细胞和血小板下降的骨髓毒性，但毒副作用可耐受，已经被认为是治疗对化疗敏感的小细胞肺癌患者的二线推荐药物，但是作为一线用药仍然需要更多的临床证据来证实。

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95％CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95％CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95％CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明，TP 方案与EP方案的反应率相似 [OR 0.83， 95%CI (0.63，1.09)]，但具有相对高的致血小板下降的骨髓毒性；单药拓朴替康与CE方案的反应率相似 [OR 0.59， 95%CI (0.22，1.60)]；TEP方案（拓扑替康＋足叶乙甙＋顺铂）与EP方案的反应率相似 [OR 1.37， 95%CI (0.82，2.28)]，TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案；口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97， 95％CI (0.60，1.57)]、中位疾病进展期 [WMD –2.32， 95％CI (–5.72， 1.09)]、中位生存期 [WMD –1.65， 95％CI (–7.13，3.83)] 相似，口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。