查询词典 knockout

Inductive interactions mediated by the Msx genes are essential for normal craniofacial, limb and ectodermal organ morphogenesis, and are also essential to survival in mice, as manifested by the phenotypic abnormalities shown in knockout mice and in humans.

基因敲除鼠和人类的畸形表现型的研究显示，Msx基因介导的诱导组织间的相互作用，对正常颅颌面、肢体和外胚层器官的形态发生至关重要。

Knockout' Mice are use for generall research and development of new treatments.internatioal efforts aim to make them avilarble in the near future for all genes.

&敲除老鼠&通常被用于普遍的研究以及新疗法的开发。国际社会旨在通过努力使得在不远的将来能够使其适用于所有的基因。

Thus gp130 is the common signal transduction molecule. Gp130 molecule expresses universally on many tissues including immune system, hemapoietic system, and nerve system. Gp130 has an essential role in the function and regulation of the above systems, especially in the development of hemapoietic system. The signal transduced by gp130 is necessary during the differentiation and proliferation of hemapoietic cells. It is evidenced that the embryo of gp130 gene-knockout mouse was dead due to a serious impediment of the development of hemapoietic system.

Gp130在人体组织细胞上广泛性表达，介导和调节机体的免疫、造血以及神经系统的生理功能，尤其是在造血系统的发育过程中，具有极其重要的作用，动物实验表明，敲除小鼠的gp130分子基因可以使其在胚胎的早期阶段产生严重的造血系统障碍，最终导致流产，由此表明在造血细胞的分化、发育和生物学行为中，gp130介导的信号是必不可少的。

Pathogenicty and immune prophylaxis of cag pathogenicity island gene knockout homogenic mutants［J］.

胃型上皮Fas表达的调节：幽门螺杆菌致病的自身免疫机制之一［J］。

Pathogenicty and immune prophylaxis of cag pathogenicity island gene knockout homogenic mutants［J］.

胃型上皮Fas表达的调节摘要：幽门螺杆菌致病的自身免疫机制之一［J］。

Hubba is a powerful prediction tool for hub/essential proteins with a user-friendly interface.Hubba can decipher the critical keys inside biochemical pathways and complex network, there will be significant clues to provide candidates for gene knockout and potential drug-targets for developing novel treatment in cancer cells and emerging pathogens.

Hubba线上分析平台，可用以分析生物复杂网路交互作用系统中的重要枢纽分子，以图像化手法呈现重要性来对枢纽蛋白质排名，并显示这些重要结点之间的关连性，协助辨识疾病细胞内与感染过程中的重要网路次模组，及特定基因群所关连的小网路，提供网路医学研究与新的治疗方法的开发。

There is an excessive hypertrophy effect in cardiomyocytes from isolated neonatal eNOS gene knockout mice under the stimulation of hypermyotrophy inducing factor.

内皮型一氧化氮合酶基因敲除小鼠其离体心肌细胞在心肌肥大诱导因子刺激下产生过度增殖反应。

According to the successful experiences on transgenic animal production and animal cloning, gene targeting could be utilized in many fields including theory and application research on genomic modification (such as site-specific gene repair, genetic defect therapy, gene knockout, infaust gene modification, even the site-specific integration), improving expression level of specific gene in animal mammary gland bioreactors, and promoting the industrialization of transgenic animal production.

结合现有转基因动物和动物克隆技术方面的经验，利用基因打靶技术，开展动物基因组修饰的理论和应用研究，即可定点进行基因修复、治疗遗传缺陷、基因敲除失活不利基因，还可最终解决动物乳腺反应器存在的随机整合率高而表达率较低的问题，实现定点整合及乳腺特异表达，为转基因动物的产业化生产创造条件，代表了当今动物遗传学发展的主流方向。

Pylori, we mutated minD gene by insertional mutagenesis and knockout minE gene of H.

此两种突变株的形态都转变成细丝状的菌体。

To study the role of FoxO1 on myoblast proliferation and differentiation and the transformation of muscle fiber type in porcine,here we use yorkshire as experimental materials and detect the expression of genes related myogenesis and muscle fiber type in pporcine myoblast that was knockout or activated FoxO1,adopting the technology of RNAi,real time-PCR and Western blotting et al..

为探讨FoxO1对猪成肌细胞增殖分化及肌纤维类型转化的作用及机理，本试验以大白猪为研究材料，利用RNAi、real-time PCR、免疫细胞化学和Western blotting等技术，通过在原代培养的猪成肌细胞中敲除和激活内源活性FoxO1，检测肌肉形成与肌纤维类型相关基因的表达。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失