查询词典 knock

METHODS:Antisense "knock-down" approach was used to inhibit MDR1 gene expression in bovine nonpigmented ciliary epithelial cells.

用反义寡核苷酸阻抑牛眼睫状体非色素上皮细胞MDR1基因表达，在激光共聚焦显微镜下检测MDR1基因反

Luciferase assay and CREB knock-down experiments further demonstrate that CREB is involved in the transcriptional upregulation of Noxa.

有意思的是，Mcl-1的蛋白水平也可以通过P13K／Akt信号通路而被CPT上调。

The archetype of the virtuously overbusy person is so ingrained in our societal mind-set that it takes strong language to knock it loose.

在我们社会性思维中，善良而过于忙碌的人这一原型是根深蒂固所以要用强烈的言辞来让它松动。

But the second knock on the door stirred her to wake up; she sat up in bed and blinked owlishly at the darkened room around her.

但是，第二次敲门终于让她醒了过来，她在床上坐起来，看着仍然被夜色隆重的房间。

It gre w strength from the young people who rejected the myth of their generation's a pathy; who left their homes and their families for jobs that offered little pa y and less sleep; it grew strength from the not-so-young people who braved the bitter cold and scorching heat to knock on the doors of perfect strangers; fr om the millions of Americans who volunteered, and organized, and proved that m ore than two centuries later, a government of the people, by the people and fo r the people has not perished from this Earth.

是从年轻人那里赢得的，他们拒绝承认自己对政治不感兴趣，他们离开家，离开亲人，干收入很少的助选的活儿，睡很少的觉。是从那些并不太年轻的人那里赢得的，他们在严冬酷暑里，勇于敲开一点也不认识的陌生人的家门。是从数百万自愿组织起来的美国民众那里赢得的。而且它也证明，两百多年后的今天，一个民有，民治，民享的政府，并没有从这个地球消失。

But when be being searched with Baidu, knock phoneticize directly, with respect to can automatic indication Chinese character.

但用百度搜索时，直接敲入拼音，就会自动显示汉字。

The disadvantage is the unknown knock-on effects. Planktonic algae are at the bottom of the food chain.

浮游藻类位于食物链的底层，假如它们的数量增多，那食物链的其它部分将会受到影响。

First, endure hardship to build the psychological line of defense: perennial cadres living in poverty in remote areas hard, there should be "located in the poor who do not sorrow," the high Polygalaceae think, to be Director-General, the Director-General can do succeed, not the cause of the Capacity, a "ring for the dark do not have to re-Raymond knock","do not have to Yangbian since Fenti" initiative, a communist party members "to the world to show concern and worry, to enjoy oneself music" psychological motive, a "power is responsibility , Is the leading service, the first to bear hardships, enjoy later,"the sense of public servants.

一是构筑起耐得住艰苦的心理防线：扶贫干部常年生活在艰苦边远地区，就要有&有志不哀地处贫&的高远志想，要有想干事、能干事、干成事、不出事的能力、要有&响鼓不用重锺敲&&不用扬鞭自奋蹄&能动性，要有共产党员&先天下之忧而忧，后天下之乐而乐&心理动机，要有&权力就是责任，领导就是服务、吃苦在前、享受在后&的公仆意识。

MATERIALS AND METHODS: Arg to Ser mutation was introduced into the 249 position of the p53 gene by knock-in method. These ES cells with this mutation were selected according to the homologues-recombination with PCR and Southern blot. The positive ES cells without a selection marker were injected into blastocysts recovered from Hprt(superscript -/-) mice, which were derived from Hprt-deficient ES cells. The injected blastocysts then were implanted into pseudopregnant females.

材料与方法：利用基因打靶技术在小鼠胚胎干细胞p53基因249编码子中引入点突变，使编码子249由精氨酸变成丝氨酸，然后将含突变的ES细胞显微注射到Hprt小鼠囊胚中，将注射过的囊胚植入假孕的雌性小鼠子宫，到第14d取小鼠胚胎纤维母细胞，用含HAT的培养液筛选出从ES细胞分化而成的鼠EF细胞，经测序证实细胞含有由249Arg到Ser的突变。

The number of pyknotic cells in the JWA knock-down cells was markedly greater than in vector control cells following CdCl_2 exposure (20μM for 12 h).

结果显示，与对照相比，当JWA蛋白表达缺陷时，加重了CdCl_2诱导的HEK-293T细胞凋亡(P＜0.05)。

Shop assistant: Please check at the door.

店员：请您到门口柜台交费。

In the end, transportation of PAHs in the environmental matrix was preliminarily investigated and discussed according to PAHs data of soils and sediments from a certain region in Shanghai. The result indicated that there are two or more pathways on PAHs transportation in the environmental matrix.

最后，对上海特定地区内PAHs在环境介质中的迁移径途进行了分析讨论，结果表明上海市土壤和沉积物等环境介质中PAHs的迁移存在多种途径。