查询词典 kir

KIR bind corresponding HLA-Ⅰmay hame four results followed:1、When inhibitory KIR bind HLA-Ⅰand there has no activatory KIR bind it,cell isn\'t dissolve because inhibitory signal access was done;2、When activatory KIR bind corresponding HLA-Ⅰand there has no inhibitory KIR bind it,form activate signal,lead cell dissolve.3、If activatory or inhibitory receptor both bind HLA-Ⅰ,both signal access is make done,when activatory signal play the main role,NK cell still actived,lead target cell dissolve.4、If activatory or inhibitory receptor both bind HLA-Ⅰ,both signal access is make done,when inhibitory signal play the main role,or both signal access don\'t play,NK cell do not make effect.this is NK cell recognice nomal tissue.

与活化型KIR受体相比，抑制型KIR受体与HLA-Ⅰ类抗原结合的亲和性更强，当抑制型和活化型KIR受体识别和结合同一HLA-Ⅰ类抗原分子时，以抑制作用为主。KIR与相应HLA-Ⅰ结合后可能产生以下4种情况：①当抑制型KIR与HLA-Ⅰ结合而无活化型KIR与HLA-Ⅰ相互作用时，因抑制信号通路启动而不产生细胞溶解；②当活化型KIR与靶细胞表面的相应HLA-Ⅰ结合同时无抑制型KIR与HLA-Ⅰ的相互作用时，形成刺激信号通路，导致靶细胞溶解。

This paper summarizes the molecular basis of PKC modulation of Kir channels and the recent progression on the area.

本文对PKC调节Kir通道机制的研究进展及目前提出的一些新观点进行综述。

In transplantation, KIR and/or HLA mismatching may lead to NK cell activation.

在移植中，KIR和/或HLA错配可能会导致NK细胞的活化。

Modulation of HLA-C and KIR interactions represents an important novel approach to promote long-term graft and patient survival.

HLA-C和KIR相互作用的调节为提高移植物和患者的长期存活率提供了一种全新的途径。

The factor of disease has little effect on KIR gene.

KIR基因受白血病类型影响较小。

Both these gene systems are polymorphic and an association of particular maternal KIR/fetal HLA-C genotypes has been shown in pre-eclampsia.

这些基因都是多态的，且特定的母体KIR与胎儿HLA-C基因型已在先兆子痫中被发现。

KIR molecule belong to immuneglobulin superfamilly,express to the surface of the NK cell and part effector T cells.

KIR分子属于免疫球蛋白样超家族，表达于NK和部分效应T细胞表面。

Condusion The KIR gene and HLAⅠ antigen are heredity independently and relatively stable.

KIR基因和HLA Ⅰ类抗原各自独立遗传，且相对稳定。

Results There were 48.72%in 78 patients who had same KIR genotypes with their siblings while the 44.87%patients had different KIR genotypes with their siblings.

结果 78例患者中有48.72%与其同胞有相同的KIR基因型，44.87%的患者与其同胞不完全相同。

ABSTRACT Purpose: The purpose of this study was to detect expression and localization of kir2. 1 and kir4. 1 in bovine retina, identify the molecular basis of the apical membrane K〓 conductance in native bovine retinal pigment epithelium , study localization of Kir channels in different species and development of Kir channels in murine retinae.

目的：本研究在mRNA和蛋白水平探讨在牛视网膜内Müller细胞的Kir2.1和Kir4.1的表达和分布及其功能，Kir7.1在牛视网膜色素上皮细胞的表达和分布；同时研究三种Kir通道在不同种属大鼠、猴和人的视网膜的分布及在大鼠视网膜中发育情况。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。