查询词典 kinases

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

With the use of Bayesian Information Criterion on the selection of model parameters, iHMM tries to avoid the known over-fitting problem when the sizes of data sets are not large. This thesis established 18 data sets of annotated kinases family such as PKA, PKC, CDK, etc from the Phospho.

藉由搭配使用贝氏资讯准则的模型参数选择方法，使HMM-2 在资料集不够大时能尽量避免众所周知的过度适化问题。

Suum and parasitic nematodes, and 7 ESTs had similarities with genes of other species. Infective larvae-specific protein kinases, protein phosphatases, neuropeptide-like peptides and their precursors and enolase transcripts were abundant in the cDNA archives.

在这43个具有相似性的ESTs中，23个ESTs与23个新杆属线虫的基因序列具有相似性，13个ESTs 与9个猪蛔虫和其它寄生线虫的基因序列具有相似性，7个ESTs 与其它物种的基因序列具有相似性。

Pyruvate dehydrogenase kinases (PDKs 1-4) can regulate the activity of mitochondrial pyruvate dehydrogenase complex to catalyse the oxidative decarboxylation of pyruvate, and then to link glycolysis to the tricarboxylic acid cycle and ATP production.

丙酮酸脱氢酶激酶具有能够调节线粒体丙酮酸脱氢酶复合体催化丙酮酸脱羧氧化的活性，并进一步将糖酵解与三羧酸循环以及ATP的生成联系在一起。

In this study, nonionic surfactant sorbitan trioleate (Span 85) was modified with Cibacron Blue F-3GA to become an affinity surfactant (CB-Span 85) and to form affinity-based reversed micelles while dissolved in hexane. Since the CB molecule possesses a specific conformation that mimics nicotinamide adenine dinucleotide, it can bind strongly and specifically to a wide range of nucleotide-dependent enzymes such as dehydrogenases and kinases. Moreover, high protein transfer efficiency in the reverse micelles can be easily achieved by controlling the ionic strength of the aqueous phase.

本实验使用非离子型界面活性剂Span 85与蓝色染料分子Cibacron Blue F-3GA结合，形成具有亲和性的界面活性剂 CB-Span 85，由於CB染料分子具有与NAD+相似的结构，可与含核苷酸部位的蛋白质具有亲和力，将CB-Span 85溶於有机溶剂形成反微胞相，可有效的提高反微胞的选择率，可以只控制离子强度来调节蛋白质进出反微胞的效率。

Another part of the project is isolation and characterization of calcium /calmodulin -dependent protein kinases.

另一部分工作是分离和鉴定烟草的钙调素依赖型蛋白激酶。

In this study, we investigated whether calcium-dependent kinases were involved in ERKs cascade activation after global cerebral ischemia.

方法采用四动脉结扎诱导大鼠前脑缺血，用免疫印迹的方法观察几个钙依赖性蛋白激酶含量及活性的变化。

Mechanical strains also regulated the protein and mRNA expression of several differentiation markers, as well as the activation of extracellular signal-regulated kinases, p38 MAP kinase and protein kinase B in a frequency-dependent manner. Furthermore, the inhibition of p38 pathway could block the strain-frequency induced the phenotype modulation of VSMCs, neither ERKs nor Akt. Frequency of mechanical strain, not conditioned medium, regulated the phenotype of VSMCs in a frequency-dependent manner. Rho-GDI alpha was suppressed by the mechanical strain at 1Hz.

采用免疫细胞化学法检测VSMCs形态和排列的变化；RT-PCR和Western blotting检测表型标志分子α-肌动蛋白、肌球蛋白重链(SM1/2)、肌动蛋白相关蛋白SM22α和调宁蛋白(h1-calponin)的mRNA和蛋白水平的变化；抑制剂或RNA干扰阻断可能的信号调节分子的活性或表达，包括p38、细胞外信号调节激酶1/(2extracellular signal-regulated kinases， ERK1/2)、蛋白激酶B和Rho-鸟苷酸解离抑制因子(Rho-guanine nucleotide dissociation inhibitor， Rho-GDI alpha)，研究了不同频率张应变对VSMCs表型转化的影响及其调节机制。

Cyclin-dependent kinases has effects on cell cycle by modulating function of eukaryon organism.The functions have been further studied in cell cycle and the process cell cycle,which will be beneficial to explain tumorigenesis pathomechanism and the new way of oncotherapy.

细胞周期素依赖性激酶是调节真核生物细胞周期的关键分子之一，深入研究细胞周期素依赖性激酶在细胞周期与细胞生长中的作用，对于阐述肿瘤发生、发展的病理机制以及肿瘤治疗的新途径具有重要的意义。

Objective To investigate the effect of extracellular signal-regulated kinases signal transduction in the process of NSCs differentiating into neurons in the fimbria-transected hippocampi's extracts. Methods Twelve Sprague-Dawley rats'right fimbrias were transected.

目的 探讨细胞外信号调节激酶信号转导通路在海马提取液诱导神经干细胞向神经元分化过程中作用。

Dixie itself is a nickname for the American South.

Dixie 本身是美国南部的别称。

I think John Terry epitomises that and a big reaction is what we will be looking for.

而我认为特里就是这样一个典型，他正是我们期望看到的那个领秀。