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Finally, it is possible that serially passaged cells, such as the Madin-Darby canine kidney cells now widely used in influenza laboratories, became latently and serially infected with different strains of influenza as a result of lax laboratory practices.

最后,它有可能是病毒连续通过细胞,如Madin-Darby canine kidney 细胞(目前广泛使用在流感实验室),导致不同流感病毒毒株潜在地及连续地感染,作为一个不严格实验室做法的结果。

ASCL2 gene escapes genomic imprinting in skeletal muscle,fat, heart,liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(2) Both of the transcripts of NNAT gene is paternally expressed in skeletal muscle,fat,heart, liver,spleen,lung,kidney,stomach,small intestine,uterus,ovary and pituitary.(3) DIRAS3 gene is paternally expressed in skeletal muscle,fat,heart,liver,spleen,lung, kidney,stomach,small intestine,uterus,ovary and pituitary.(4) DLX5 gene is maternally expressed in skeletal muscle,fat,spleen,lung,stomach,small intestine,but escapes imprinting in heart,liver,kidney,uterus,ovary,testicle and pituitary.

1ASCL2基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均逃脱印记;(2)NNAT基因两个转录本在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中均为母系印记:(3)DIRAS3基因在肌肉、脂肪、心、肝、脾、肺、肾、胃、小肠、子宫、卵巢和垂体中母系印记:(4)DLX5基因在骨骼肌、脂肪、肺、脾、胃和小肠中表达母本来源的等位基因,即表现为父系印记;而在心、肝、肾、子宫、卵巢、睾丸和垂体中表达双亲来源的等位基因,即逃脱印记。3。

AS an ideal method to evaluate kidney function,especially for the individual kidney,~(99m)Tc-DTPA renography could accurately analyst the preoperative individual kidney function and postoperative recovery for IVP non-visualize kidneys,It was useful in directing the selection of operation methods and providing objective proof of making correct decision on weather preserved the defected kidney or not.

做为评价肾功能尤其是分肾功能的理想方法,~(99m)Tc-DTPA肾动态显像准确的评估IVP不显影患肾术前分肾功能及术后功能恢复情况,从而为临床上手术方式的选择及患肾的保留与否提供客观依据。

Demonstrative green tea can reduce gland purine to be damaged to the qualitative pathology between bandicoot kidney, green tea has fight the action that qualitative fiber changes between kidney, and can restrain hyperplasia of fibrous of I,Ⅲ collagen, this may be green tea qualitative fiber is changed between kidney of prevention and cure, one of mechanisms that defer chronic kidney failure to develop a process.

说明绿茶能够减轻腺嘌呤对大鼠肾间质的病理损害,绿茶有抗肾间质纤维化的功能,并且能抑制I、Ⅲ型胶原纤维的增生,这可能是绿茶防治肾间质纤维化、延缓慢性肾衰竭发展进程的机制之一。

Results Of the 21 patients, 5 showed transplanted kidney swelling alone, 8 showed transplanted kidney swelling and perinephric dropsy, 1 showed atrophy and function failure of both kidney, 2 showed perinephric hemorrhage, 1 showed multiple small cysts, small calculi and perinephric dropsy of transplanted kidney, 1 showed ureteral fistula, ureteral stricture, hydronephrosis and infarct of subsegment kidney, 1 showed hydronephrosis and ureteral calculi, 1 showed swelling and pyonephrosis, and 1 showed rupture of transplanted kidney.

结果 21例患者中5例仅表现为移植肾肿胀,8例表现为移植肾肿胀并肾周积液;1例为双肾萎缩伴功能丧失;2例表现为移植肾周积血;1例表现为移植肾多发小囊肿、小结石并肾周积液;1例表现为移植肾输尿管旁尿瘘伴输尿管狭窄及肾积水、亚段肾梗死;1例表现为移植肾积水并输尿管结石;1例表现为移植肾肿胀,肾盂内积脓;1例表现为移植肾破裂。

BMP-7 expression was lower markly in Lung-kidney Qi Deficiency 、Liver-kidney yin Deficiency、 Qi-yin asthenia、Speen –kidney Yang Deficiency than normal control. BMP-7 expression decreased with Lung-kidney Qi Deficiency 、Liver-kidney yin Deficiency、 Qi-yin asthenia、Speen –kidney Yang Deficiency.It shows that the level of BMP-7 expression may play a role in Zheng differentiation-classification of TCM of the chronic glomerulonephritis.

中医证型与肾间质纤维化程度显著相关,肺肾气虚、肝肾阴虚型纤维化程度最轻,气阴两虚型其次,脾肾阳虚型纤维化程度最重,提示传统中医辩证分型与纤维化程度有关,在一定程度上可以反映慢性肾小球肾炎组织学损伤程度,肾间质纤维化程度可作为中医临床辨证参考依据。

Objective:To observe how promote kidney and tonify bone herbs to regulate hematopoiesis regulation factors of kidney deficient chronic aplastic anemia patients,and discuss relativity between different kidney deficiency syndromes and hematopoiesis regulation factors,and regulation mechanism of kidney promote herbs.

目的: 观察补肾益髓法中药对慢性再障肾虚患者造血调控因子的调节作用,探讨不同肾虚证与造血调控因子之间的相关性及补肾中药的调节机制。

This may be explained by follows: First, Decoction Shenkangling can regulate the homeostasis of NEI network and reduce the increased activity of NF-κB to restrain the action of inflammatory-sclerotic media; Second, it can redress the disequilibrium of the ratio of TXA2/PGI2 to reform the hypercoagulable state; Third, it can enhance albumin and reduce cholesterol and triglyceride; Fourth, it can amend the renal damage and protect the function of renal tubule and stroma to prevent the transformation from MCD to FSGS; Last, it can lessen urine protein in AN rats markedly and relieve the side effects of prednisone.4. NF-κB, TXA2 and PGI2, along with the renal pathomorphology and so on can all be the indexes of the diagnosis of Symptom of "Kidney Deficiency and Blood Stasis" and the application of Methods of "Benefiting the kidney and Promoting blood circulation" in TCM.5. The curative effects on AN rats by treatment of integrating Traditional Chinese Medicine with prednisone are much better than using prednisone only. And the curative effects on AN rats by treatment of matching Decoction Shenkangling, having the function of "Benefiting the kidney and Promoting blood circulation", with Prednisone are much better than using Prednisone only.6. When it referred to decreasing urine protein, cholesterol and triglyceride and increasing albumin, Decoction Zhibodihuang excesses Decoction Taohongsiwu. However, when it referred to regulating the disequilibrium of TXA2/PGI2 and meliorating renal lesion, Decoction Taohongsiwu exceeds Decoction Zhibodihuang.7. The curative effects on AN rats by treatment of matching Methods of "Benefiting the kidney and Promoting blood circulation" with Prednisone overmatches using Prednisone matching Method of "Benefiting the kidney" or Method of " Promoting blood circulation" only.

益肾活血中药肾康灵能显著改善AN鼠的肾虚血瘀证的临床表现和实验指标,这可能与中药肾康灵能调理AN鼠机体的NEI网络功能稳态,降低异常升高的NF-κB活性,抑制免疫炎症/硬化介质环节,纠正失衡的TXA2/PGI2,改善AN鼠血液高凝状态,提高AN鼠的血清Alb,降低Ch和TG,减轻AN鼠的肾脏组织病理学变化,保护肾小管-间质功能,阻止MCD向FSGS转化;显著减轻AN鼠的尿蛋白水平以及减轻激素副作用有关。4、NF-κB、 TXB2和6-keto-PGF1α以及肾脏病理形态学改变等,都可作为中医肾虚血瘀证诊断和益肾活血法应用的客观指标。5、中西医结合干预AN鼠疗效优于单纯激素治疗;强的松配合益肾活血中药肾康灵组的综合疗效显著优于单纯强的松组。6、知柏地黄汤组在降低尿蛋白、提高血清Alb、降低Ch和TG疗效上优于桃红四物汤组;桃红四物汤组在纠正失衡的TXA2/PGI2和减轻肾脏病理损害方面优于知柏地黄汤组。7、激素配合益肾活血法干预AN鼠在一定程度上优于激素配合益肾法或活血法。

Objective Through observing the ei'fect of the TCM decoction TangShenHuaYuJian on the kidney weight, index of kidney hypertrophy(kidney weight/body weight), blood glucose , blood urea nitrogen, creatinine, blood advanced glycation end-products, advanced glycation end-products in kidney tissue in the earlier stage of diabetic nephropalhy rats induced by injecting 3 -cytotoxins into abdomen, to explore the relationship between nonenzymatic glycosylation and diabetic nephropathy, and provide an experimental basis for clinical application and for further studying TSHYJ.

目的 通过观察糖肾化瘀煎对长期高血糖所致的早期粮尿病肾病大鼠(腹腔注射链脲佐菌素后诱导所形成)肾重、肾重指数、血糖、血尿素氮、肌酐、血糖基化终末产物AGEs、肾组织糖基化终末产物AGEs等指标的影响,从非酶糖基化角度探讨此制剂对糖尿病肾病早期的作用机理,并为糖肾化瘀煎的临床运用和进一步开发提供实验依据。

The treatment comparison by using Chinese TANG Kidney capsule and Western medicine TANG SHI PIN showed: the kidney capsule can lower the values of the blood sugar, blood fat, series of micro-protein un urine and carbon monoxide in plasma, thus the function of kidney can be improved, and prolong the process of deadness and hardening of the affected kidney small cell fibre.

利用该模型选择中药糖肾胶囊与西药糖适平对照治疗研究,结果显示:糖肾胶囊能降低糖尿病肾病大鼠的血糖、血脂、尿素氮、肌酐、尿系列微量蛋白及血一氧化氮等指标,从而减轻糖尿病肾病大鼠肾小球的高灌注高滤过,降低糖化血红蛋白含量,减轻非酶糖基化,改善肾功能,降低血脂、内皮素、调节血栓素、前列腺素水平,有抗脂质过氧化损伤的作用。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。