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Lung concentration-time data after oral administration of 50mg/kg body weight we re also best d escribed by a two-compartment open model. The parameter of male chicken were as following: t1/2 a 为 2.28S±0.657h , t1/2Ka1.090±0.193h, t1/2B 为 37.606±4.474h, AUC530.797±48.050*h, CL 0.095±0.008mg/kg/h/, Tmax 5.256±0.442h, Cmax 9.044±0.016ug/g.

公鸡肺脏主要的药代动力学参数:t1/2 α为2.285±0.657h、t_(1/2Ka)为1.090±0.193h、t_(1/2β)为37.606±4.474h;AUC为530.797±48.050~*h、CL为0.095±0.008mg/kg/h/、T_为5.256±0.442h、C_为9.044±0.016μg/g;母鸡肺脏主要的药代动力学参数:t_(1/2α)为1.556±0.825h、t_(1/2Ka)为0.732±0.101h、t_(1/2β)为23.304±2.320h;AUC为395.073±12.095~*h、CL为0.127±0.004mg/kg/h/、T_为3.584±0.440h、C_为10.691±0.542μg/g。

Another 72 mice were randomly divided into control group,egg yolk model group,Expellant and Cleanning Fat Capsule 0.4 g·kg-1 group,CFB 10.0,5.0,2.5 mL·kg-1 groups (n=12).Mice in each group were exhibited once a day for 10 d.16 h before the last administration,except control group,the mice in other groups were injected with 75% yolk physiological salt solution 0.5mL through the abdominal cavity,and began to starve,1 h after the last administration, the contents of serum TCHO and TG were determined,and liver MDA level was measured.

另取小鼠72只随机分为空白对照组、蛋黄模型组、排毒清脂胶囊0.4 g·kg-1组及CFB 10.0、5.0和2.5 mL·kg-13个剂量组( n=12),每天给药1次,连续 10 d,末次给药前16 h 除空白对照组外,所有各组小鼠每只均腹腔注射75%蛋黄生理盐水溶液0.5 mL,并且开始饥饿;末次给药后1 h测定血清TCHO及TG含量,取肝脏测MDA含量。

CFB 7.0 mL·kg-1was superior to Kanglishu Capsule in reducin g TCHO,TG and MDA,CFB 10.0 mL·kg-1 was superior to Expellant and Cleanning Fat Capsule.

在降低TCHO和TG含量及小鼠肝脏MDA水平方面CFB 7.0 mL·kg-1组优于康立舒胶囊组,CFB 10.0 mL·kg-1组优于排毒清脂胶囊组。

Methods Animals were randomly and equally divided into five groups: saline control group, positive drug control group, low-dose, medium-dose and high-dose crocetin group. Animals were anesthetized with urethane (1.2 g/kg), then followed by the perfusion of aconitine (10 μg/mL) through caudal vein in rats, or of ouabain (9 μg/mL) through external jugular vain in guinea pigs in a constant velocity of 0.1 mL/min, and the emergence time of ventricular fibrillation, ventricular extrasystole, ventricular tachycanlia and cardiac arrest were then detected and recorded. The recorded time was then translated to the cumulated amount of aconitine and ouabain. Experimental arrhythmia was induced by rapid injection of 4% CaCl2 (140 mg/kg), and the emergence time, persistence time, incidence and death of arrhythmia after the administration were observed.

将实验动物随机分为生理盐水组,阳性药物对照组,藏红花酸高、中、低剂量组,SD大鼠采用1.2 g/kg乌拉坦麻醉后,从尾静脉匀速(0.1 ml/min)灌注10μg/ml乌头碱溶液,豚鼠麻醉后从颈静脉匀速(0.1 ml/min)灌注9μg/ml哇巴因溶液,观察出现室性期前收缩、室性心动过速、室颤和心脏停搏的时间,然后换算成乌头碱和哇巴因的累积量;快速推注4%氯化钙(140 mg/kg)诱导大鼠心律失常,观察给药后心律失常出现时间、持续时间、心律失常发生数及死亡数。

Gelsemium total alkaloids improved some blood and immune function of mice when it less than 0.30mg/kg body weight, but more than 1.5mg/kg body weight, the gelsemium total alkaloids can reduced some blood and immune function of mice; below the dose of 3%, GEB"s power can improve some blood and immune function of broilers, but GEB"s power can reduce some blood and immune function of broilers above the dose of 6%.

结论是:钩吻对小鼠和肉鸡的血液学及免疫功能的影响均存在着剂量差别,钩吻总碱稀释液在0.30mg/kg剂量以下,能够提高小鼠的某些血液指标与免疫功能(p<0.05),而在1.5mg/kg以上,则降低小鼠的某些血液指标与免疫功能(p<0.05);3%以下的钩吻干粉能够提高肉鸡的某些血液指标与免疫功能,而6%以上的钩吻干粉则降低某些血液指标与免疫功能。

The normal control group, hyperlipidemia model group, high dose of perilla seed group (2.5 g/kg), low dose of perilla seed group (0.83 g/kg) were designed to measure the contents of total cholesterol, three acids glyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, very low density lipoprotein cholesterol and malondialdehyde, superoxide dismutase activity.

方法]采用高脂饮食建立鹌鹑高脂血症模型,分别测定正常对照组、高脂模型组、紫苏籽高剂量组(2.5g/kg)、低剂量组(0.83g/kg)血清中总胆固醇、甘油三脂、高密度脂蛋白、低密度脂蛋白、极低密度脂蛋白、丙二醛含量及超氧化物歧化酶的活性。

Result Red Globe grape tree kept vigorous growth than the control with 20 mg/kg GA treatment; the yield per plant, leaf area, fruit weight and diameter of Red Globe grape were significant differences than the control treated with 10 mg/kg GA, comparing with control, increased by 18.92%, 13.08%, 24.51% and 9.44%, resp..

结果]用20mg/kg赤霉素浓度处理的红地球葡萄树体较对照生长旺盛;用10mg/kg赤霉素浓度处理的红地球葡萄树体的单株产量、叶面积、粒重和粒径均较对照差异显著,分别比对照增加18.92%、13.08%、24.51%和9.44%。

The fixed-NH+4 capacity of all natural layers in lou soil was determined in this thesis,they were 482.2±10.4,1134.9±4.0 and 553.0±11.3 mg N/kg soil in overburden layer,claying horizen and loess parent material horizen respectively.

确定了土娄土各自然层的固定态铵容量,覆盖层、粘化层和黄土母质层分别为(482.2±10.4) mgN/kg、(1134.9±4.0) mgN/kg和(553.0±11.3) mgN/kg土。

Forty patients were divided at random into two groups with 20 patients in each group.Patients in group I were administered by themselves a mixture of propofol (20mg) and fentanyl (10μg) in increments using a Graseby PCA infuser (lockout period 1 min) to achieve sedation;patients in group Ⅱ received propofol 3.6mg .kg-1.h-1 and fentanyl 1.8μg-1.kg-1.h-1 continuously intravenously by the anesthesiologist to achieve intra-operative sedation.

40例下腹部手术病人随机分为两组(n=20),PCS组病人应用Graseby PCA 注射泵(锁定时间1分钟)自我控制用药,PCS单次用药量为异丙酚20mg加芬太尼10μg;DCS组病人微量泵连续静注异丙酚3.6mg.kg-1.h-1和芬太尼1.8μg.kg-1.h-1。

Nimals in intervenor groups were irrigated allyl chloride (200mg/kg)into stomach,or injected Znpp(45umol/kg)into peritoneums once a day.

QP4干预组予以氯丙烯(200mg/kg)灌胃,HO-1干预组予以ZnPP(45umol/kg)腹腔注射,均为每天一次。

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The split between the two groups can hardly be papered over.

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The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

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