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Methods:One hundred and seventeen patients were randomly divided into study group(n=66) and control group(n=71). The patients in two groups receive isoenergetic(104.5 kJ.kg-1.d-1) and isonitrogenous (0.2 g.kg-1.d-1) TPN from postoperative first day to the seventh. Whereas the study group received additional 0.4g.kg-1.d-1 of Ala-Gln.

137例胃肠道肿瘤患者术后被随机分为研究组 66例和对照组 71例,所有患者术后第1~7 天给予TPN,等热量(104.5 kJ.kg-1.d-1)、等氮(0.2 g.kg-1.d-1),研究组另加入Ala-Gln注射液0.4 g.kg-1.d-1。

Sugar water choosed degree have no significant change. It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进,降低慢性应激所致IBS模型大鼠的内脏敏感性,显著减少了IBS模型大鼠的排便数量,从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的:探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

It means that Iridoids composition of Valeriana jatamansi Jones has central inhibitory action.2.2 Effection of Iridoids composition of Valeriana jatamansi Jones on weight and food intake of IBS rats induced by chronic stressAnimals were randomly divided into 7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

蜘蛛香环烯醚萜可以减缓正常小鼠的胃肠运动和利血平化小鼠的胃肠功能亢进,降低慢性应激所致IBS模型大鼠的内脏敏感性,显著减少了IBS模型大鼠的排便数量,从而改善腹泻型IBS的临床症状。2蜘蛛香环烯醚萜对神经系统功能的影响目的:探讨蜘蛛香环烯醚萜对精神活动的影响2.1蜘蛛香环烯醚萜对慢性应激所致IBS大鼠精神活动的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时,蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数,说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环烯醚萜对外周和中枢5-HT含量的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环(来源:49ABC论文网www.abclunwen.com)烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时,蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数,说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环(来源:5bABd5C论文网www.abclunwen.com)烯醚萜对外周和中枢5-HT含量的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It may means that Iridoids composition of Valeriana jatamansi Jones doesn\'t regulate the TPH1 transcription expression.3.4 Effection of Iridoids composition of Valeriana jatamansi Jones on SP and VIP of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

造模后,中枢5-HT呈现降低趋势,这可能是导致动物出现活动能力下降和兴趣缺失的原因之一,蜘蛛香环烯醚萜可以增加下丘脑、海马和杏仁核中5-HT含量,推断蜘蛛香环烯醚萜可通过干预中枢的5-HT通路来改善IBS精神症状。3.2蜘蛛香环烯醚萜对胃肠激素的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠SP和VIP的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Juglone of600μg/kg,300μg/kg and 150μg/kg had no significant impact on tumor growth.

但600μg/kg、300μg/kg和150μg/kg胡桃醌对肿瘤生长没有明显的影响(P均>0.05)。

Methods LYS polymaccharides were isolated from Millettia Pulcha Kurz vur,LaxiorZ.Wei.After the mice were treated P.O with LYS polymaccharides0.425g/kg,0.85g/kg,1.70g/kg for8days continually,the effects of the swimming time,resist anoxic time and resist heat time were investigated,theactivity of serum SOD and GSH-Px and the content of MDA were determined.

从龙眼参提取粗多糖,按0.425g/kg、0.85g/kg、1.70g/kg连续给小鼠灌胃8天,观察不同剂量对小鼠游泳时间、耐缺氧时间、耐高温时间及血清SOD、GSH-Px和MDA含量的影响。

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