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PartⅡ:Effect of bicyclol on hepatocyte apoptosis in alcohol-intoxicated mice and related mechanismsThree consecutive intragastric administration of alcohol(6g/kg)in 12h interval resulted in an obvious liver injury and inflammation in mice,as indicated by the elevation of serum alanine transaminase(2.2 fold of control),increased hepatic COX-2 protein expression(2.2 fold of control),as well as liver pathological changes characterized by myelonic degeneration,vacuolar degeneration and inflammatory infiltration.

双环醇对酒精中毒小鼠肝脏细胞凋亡的保护作用及机制研究小鼠连续三次酒精(6g/kg)灌胃后可导致明显肝损伤,变现为血清ALT水平升高(为对照组的2.2倍),肝脏炎症相关蛋白环氧合酶-2(cyclooxygenase-2,COX-2)表达增加(为对照组的2.2倍),肝组织出现髓样变性、小空泡变性和炎性细胞浸润。

IV midazolam 0.015 mg/kg administered 90 s before induction of anesthesia with etomidate is effective in reducing myoclonic movements and does not prolong recovery in unpremedicated patients after short procedures.

用依托咪酯进行诱导前90秒静脉注射0.015 mg/kg 咪达唑仑对降低肌振挛的发生是很有效的,并且在一个短暂的过程后这并不延迟未使用术前用药的病人的苏醒。

It was conducted that different doses ranging from 0.01~0.20μg/kg TBTCL intrapertoneal on the influence of TBTCL on peripheral blood T-lymphocyte and spleen index in mice by using peripheral blood lymphocyte acid α-naphthyl acetate esterase detection method,and mice body and spleen weight changes were observed.

进行了0.01~0.20μg/kg TBTCL 腹腔注射对小鼠外周血T-淋巴细胞与脾指数影响的实验,采用外周血液淋巴细胞酸性α-醋酸奈酯酶检测法,并观察小鼠体重和脾重变化情况。

METHODS: A randomized controlled study was carried out to compare the efficacy of a single dose of 3 or 2 tablets of albendazole composite versus a single dose of 400 mg of albendazole or 10 mg base/kg of pyrantel pamoate for treatment of intestinal nematodiasis including 1 864 cases infected with hookworm, 1 568 cases infected with Ascaris, 1 785 cases in...

对成人钩虫感染者1864例、蛔虫感染者1568例和鞭虫感染者1785例及儿童蛲虫感染者373例,随机分组,比较服用单剂复方阿苯达唑3片或2片与单剂阿苯达唑400mg或噻嘧啶30mg(含基质10mg)/kg的驱虫效果和副作用。

Healthy SD male rats were given DEG with the dose of 8 mL/kg body weight (intraperitoneal injection I.P.). The level of the serum Cr, BUN and CO2CP(CO2 Combining Power CO2CP)were tested before and after the injection the 2nd , 5th , 7th, and 14th day. The nephridial tissue of all the rats was taken for pathological examinations.

选用健康雄性SD(Sprague-Dawley)大鼠,腹腔注射8 mL/kg的DEG,于注射前和注射后第2天、5天、7天以及14天尾静脉采血检测血肌酐、尿素氮和CO2结合率(CO2CP),收集死亡大鼠及第7天和14天处死大鼠的肾组织进行病理检查。

Methods The rat models of neuroglioma were established,and divided into two groups. The rats in experimental group were lavaged with MMC 1 week after injected with C6 glioma cells, 10 mg.kg-1every day,the rats in control group were treated with sodium chloride at the same dose.

制备大鼠脑胶质瘤动物模型,将造模成功的大鼠随机分为对照组和实验组,实验组大鼠注射C6脑胶质瘤细胞1周后,每天灌胃给予10 mg.kg-1MMC,连续5 d;对照组给予相同体积的生理盐水。

Methods Experimental group were lavaged with MMC for 5 d and 10 mg/kg BW per day after the conduction of the athymic rat model of neuroglioma, control group was given with sodium chloride at the same dose.

制备裸鼠皮下U251胶质瘤模型,随机分为对照组和实验组,实验组裸鼠注射U251脑胶质瘤细胞1 w后,每天灌胃给予10 mg/kg体重MMC,连续5 d,对照组给予相同体积的生理盐水。

130 patients of nonrupture ectopic pregnancy were treated with methotrexate、methotrexate combining Mifepristone(RU 486),methotrexate was given systemically(5×0.4mg/kg i.v.).

130例非破裂型宫外孕患者分别进行MTX、MTX联合RU4 86治疗,MTX用法为 0 4mg/kg,每日 1次,5次为 1疗程,间歇 7天,RU4 86 5 0mg每 12h口服 1次,共 3天。

The rats in treatment group were giving tiopronin once a day at a dosage of 100 mg/kg and those in nontreatment group were fed with copper overloaded diet,however,the rats in control group were fed with normal diet.

用铜负荷饮食法制作HLD动物模型,将模型大鼠分为治疗组与非治疗组,治疗组给予MPO 100 mg·kg-1·d-1灌胃,非治疗组继续给予铜负荷饮食,对照组大鼠传统饮食喂饲。

RESULTS:Using nubilous inhalation or intragastric administration,artesunate significantly inhibited the guinea-pig model asthma in a dose-dependent manner.Its ED50 were (99.95±7.69)mg.L-1(n=4) and (15.64±1.25)mg.kg-1.d-1(n=4) respectively.

结果:雾化或灌胃给药,青蒿琥酯均对药源性哮喘呈现剂量依赖性明显的抑制作用,其半数有效剂量(ED50)分别为(99.95±7.69)mg.L-1(n=4)和(15.64±1.25)mg.kg-1.d-1(n=4),其抑制作用与给药的剂量之间呈良好线性关系。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。