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Results:Arterial blood pressure was apparently decreased by 10 mg/kg losartan intraperitoneally,but heart rate did not change;63.64%(21/33) unit dischargings of habenular neurons was increased in the rate of discharges.

结果:腹腔注射10 mg/kg芦沙坦可显著地降低大鼠动脉血压,但对心率无明显的影响;芦沙坦可使缰核64%(21/33)自发单位放电的放电频率增加。

Methods The mouse models bearing S180 sarcoma were treated with cadmium chloride with dosages of 0.25,1.00 and 4.00 mg.kg-1,the anti-tumor effect was evaluated by calculating of tumor weight;spleen and thymus indexes,carbon phage assay,lymphocyte transformed assay and hematolysis assay were used to measure the effect of cadmium chloride on immune function.

应用0.25、1.00及4.00 mg.kg-1的氯化镉处理S180肉瘤小鼠模型,检测瘤重确定氯化镉对S180肉瘤的抑瘤作用,采用胸腺指数、脾脏指数、碳粒廓清试验、淋巴细胞转化实验、半数溶血素实验检测小鼠免疫功能的变化。

Methods Whole boold, heparinized blood, thrombin or saline were infused into the right caudate nucleus of rats in a stereotactic frame. Twenty rats were treated with hirudo powder (250mg/kg, twice daily for 5d, po). Brain water and electrolyte levels in these rats were measured at different times.

分别制作大鼠自体全血、凝血酶、肝素抗凝血、生理盐水及假手术脑血肿模型,观察不同时间血肿周围脑组织含水量,Na、K含量的变化以及病理改变;并观察水蛭粉(250mg/kg口服,每天2次,治疗5d治疗脑水肿的疗效。

QFM preparation was administrated at the doses of 0.1 ml/kg body weight intravenous in 10 dogs. The changes of homodynamic and levels of serum nitric oxide, plasma endothelin, PGF1α and thromboxane A2 were examined before and after the dogs being administrated with QFM preparation.

试验选取10条健康犬静脉注射QFM合剂0.1 ml/kg体重,观察比较了注药前后犬血液动力学变化和血清一氧化氮、血浆内皮素、前列环素及血栓素A2含量的变化。

Mg/Kg , a kind of hydragogue, had weaker effect than higher dose of tea catechins.

利尿剂——氢氯噻嗪(5.7mg/kg)的利尿作用弱于大剂量茶儿茶素(p.05),峰时为0.5~1.0h。

RESULTSWhen the dosage of the Aipingxiao were 13.0, 6.5g/kg by intragastric administration, the inhibition rates was 34.2%, 28.1% in the transplantation with S180 Sarcoma, the inhibition rates were 50.8%, 40.8% with H22 liver cancer, the inhibition rates were 74.2%, 57.0% with Lewis lung cancer, respectively. The survival rate increased significantly in the hydroperitoneum type of transplantation with H22 liver cancer more than model group.

结果]分别以13.0,6.5g/kg剂量的癌平消灌胃给药,对小鼠移植性S180肉瘤增殖的抑制率分别为34.2%,28.1%,对小鼠移植性H22肝癌实体瘤增殖的抑制率分别为50.8%,40.8%,对Lewis肺癌实体瘤增殖的抑制率分别为74.2%,57.0%,H22肝癌腹水型小鼠的生存时间明显延长,与模型组比较均有显著性差异。

Methods A rabbit was celiac-perfused by 5-Fu 100mg/Kg.Then assayed the durg concentrations of janitrix,abdominal aorta,peripheral venous,hydroperitoneum and tissues of liver and kidney by liquid chromatography in specific time;60 cases of hepatocellular carcinoma were radomized into experimental group and placebo group .

实验用家兔腹腔内注入5- Fu 100mg/kg,分别于设定时间抽取门静脉,腹主动脉,外周静脉血,腹腔液,肝、肾组织标本采用高效液相色谱法测定药物浓度;选择中晚期失去手术机会的临床确诊原发性肝癌病人60例,随机分组为实验组(行肝动脉化疗栓塞术中联合腹腔序贯化疗)和对照组(单纯行肝动脉化疗栓塞术)。

Diabetes was induced by streptozotocin (55 mg/kg body wt by intraperitoned injection) which was dissolved in citric acid-phosphate buffer PH4. 4 and verified 24 hours later by the presence of hyperglycemia and hyperglycosuria.

糖尿病模型制备方法按55mg/kg STZ剂量向大鼠腹腔内一次性注射链脲佐菌素(Streptozotocin,STZ),STZ予先溶于PH4.4的柠檬酸—磷酸氢二钠缓冲液中,制成浓度为20mg/ml溶液。24h后测尿糖和血糖,尿糖在+++和++++,血糖在16mmol/l以上者确定为糖尿病。

ResultsAvermectin acute oral LD50 was 43.0 mg/kg, which defined as hypertoxic.

结果 阿维菌素原药急性经口LD50为43.0mg/kg,为高毒。

To explore the influence on the expression of orexin A in the hypothalamus and orexin type 1 receptor (OX1R) in the medulla of neonatal rats after prenatal nicotine exposure, the 20 pregnant rats were divided into 2 groups randomly. Either nicotine (6 mg/kg per day) or normal saline solution (as same volume as nicotine group) was administered into the pregnant rats hypodermically from the fifth day to the end of gestation.

为了观察出生前尼古丁暴露对新生大鼠下丘脑orexin A及延髓内orexin 1型受体(OX1R)表达的影响,本实验将20只雌性成年大鼠随机均分为二组,怀孕后第5 d开始每天分别皮下注射尼古丁6 mg/kg或等量的生理盐水,直至分娩。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。