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The ED50 and ED90 of QHS are (10.2±1.3) and (29.0±2.7) mg/kg/d respectively; and those of QHH (Qinghaosu:Qinghao acid:Qinghao B:Scopoletin=1:1:1:1) are (12.6±1.1) and (47.0±5.7) mg/kg/d respectively.
将青蒿素、青蒿酸、青蒿乙素、东莨菪内酯按1:1:1:1混合得到QHH,其ED50和ED90分别为(12.6±1.1)mg/kg/d和(47.0±5.7)mg/kg/d。
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Methods: The skeletogenous cells which were taken from cranial bones of SD rats cultivated, and were devided into 4 groups, the culture solution of which were added in order rabbit serum without No1 Guyu, and with No1 Guyu of density 12.5g/Kg, 25g/Kg, 50g/Kg.
从新生SD大鼠颅骨获取成骨细胞进行培养,取第3代成骨细胞进行试验,将其分为4组,在各组培养液中分别加入不灌胃骨愈l号的新西兰兔血清和灌胃骨愈1号浓度分别12.5、25、50g/kg的新西兰兔血清。
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Results The mortality rate of mice in 80 mg/kg, day cyclophosphamide group was 16.7%, and T level [ at 30th day :( 1.38 ± 0.31 );45th day:( 1.15 ± 0.26 ) ] and T/LH ratio [ at 30th day:(0.163 ± 0.014); 45th day:(0.127 ± 0.023 ) ] were significantly decreased (all P<0.05) at 30th day after induction;The concentration of MDA [at 15th day:(2.70 ± 0.41);30th day:(2.710.36);45th day:(2.67 ±0.43) ] was maintained at a high level (all P<0.05) during the 45 days ; Number of Leydig's cells [ at 15th day:(9.65 ± 0.75 ); 30th day:( 14.05 ± 0.67 ); 45th day:(8.49 ± 072)] and layers of spermatogenetic epithelia [ at 15th day:(4.75 ± 0.82);30th day:(3.60 ± 0.49);45th day:(3.74 ± 0.43 ) ] were significantly decreased ( all P < 0.01 ) and stabilized in a low level. The induced model was stable and the mortality rate was acceptable. In the 60 mg/kg, day cyelophosphamide group, the T level and T/LH ratio had no significant change (P > 0.05 ), and the concentration of MDA ,number of Leydig' s cell and layers of spermatogenetic epithelia recovered at 30th day after induction. The induced model was unstable.
结果 剂量每日为80 mg/kg体重小鼠成模后死亡率为16.7%,血清T[30 d:(1.38±0.31);45 d:(1.15±0.26)]及T/LH比值[30 d:(0.163±0.014);45 d:(0.127±0.023)]于诱导后第30天出现显著下降(P均<0.05),而诱导后睾丸组织内MDA含量[15 d:(2.70±0.41);30 d(2.71±0.36);45 d:(2.67±0.43)]维持高水平(P均<0.05),生精上皮层次[15 d:(4.75±0.82);30 d:(3.60±0.49);45 d:(3.74±0.43)]和间质细胞[15 d:(9.65±0.75);30 d:(14.05±0.67);45 d:(8.49±0.72)]均显著减少(P均<0.01)并稳定于低水平,模型稳定,死亡率适当;每日60mg/kg体重组小鼠血清T及T/LH比值于不同时段并未出现明显变化(P>0.05),且睾丸组织内MDA含量、生精上皮层次和间质细胞计数在30 d后有所恢复,模型不稳定;每日100 rag/ks体重组死亡率为30.0%,死亡率过高。
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When copper sulphate was gavaged one month to mice even at the dose of 6 and 12mg/kg, DNA SSB in splenocyte of mice was apparently increased.
结果]50、100和200mg/kg硫酸铜1次染毒;25.0和50.0mg/kg硫酸铜染毒2周;6和12mg/kg硫酸铜染毒1个月后,脾细胞均出现DNA链断裂损伤的频率以及尾长均明显高于对照组。
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Male weanling Wistar rats were fed with either a basal selenium deficient diet (a Torula yeast based semisynthetic diet, containing Se 0.01 mg/kg) or a selenium sufficient diet supplemented with Se as Na\-2SeO\-3 (containing Se 0.5mg/kg). Rats were killed after different weeks(0,1,2,4,8,12,15,17,19,20 and 24 respectively).
以低硒酵母配制的低硒基础饲料(含硒量为0.01mg/kg)和在此基础上加亚硒酸钠配成硒水平为0.50mg/kg的足硒饲料来喂养雄性Wistar断乳大鼠。
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The mice in the above groups were fed for 7 days. The drug groups were pretreated intragastrically with 3, 15g · kg-1 celery root; bifendate pills groups were pretreated intragastrically with 200mg · kg-1 bifendate. Control animals were given the same volumn physiological saline.
高、低剂量给药组按30、15g · kg-1灌胃芹菜根提取物,阳性对照组按200mg · kg-1灌胃联苯双酯滴丸,阴性对照组及模型对照组以等体积生理盐水灌胃,共7d 。
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When the influent pH was controlled between 7.5 and 8.0, the maximum sulfide and nitrate removal loading rate were 2.96 kg��(m3·d)-1 and 0.47 kg��(m3·d)-1, respectively.The basifying reaction and remnant sulfide led to increasing pH values that were finally beyond the bacteria toleration and caused process instability at high loading rates.
控制进水pH在7.5~8.0之间,反应器的最大容积硫化物和硝酸盐去除速率分别为2.96 kg·(m3·d)-1和0.47 kg·(m3·d)-1(分别以硫元素、氮元素计),反应过程产碱及残留硫化物,均会导致反应液pH值过高(9.11±0.38),引发高负荷时工艺失稳。
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In patients with acute PE, if IV UFH is chosen, we recommend that after an initial IV bolus (80 U/kg or 5,000 U), it is administered by continuous infusion (initially at dose of 18 U/kg/h or 1,300 U/h) with dose adjustment to achieve and maintain an APTT prolongation that corresponds to plasma heparin levels of 0.3 to 0.7 IU/mL anti-Xa activity by the amidolytic assay rather than administration as IV boluses throughout treatment, or administration without coagulation monitoring (Grade 1C).
急性PE患者,如果选择IV UFH,我们推荐初始快速注射80U/kg或者5000U,继之以18 U/kg/h 或 1,300 U/h持续静滴。根据APTT延长,或者监测血浆肝素水平在0.3'0.7IU/ml, amidolytic assay 分析抗Xa因子活性来调整UFH剂量,而不能持续静脉注射治疗,或者不监测凝血功能(1C)。
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Results:weijian obviously shortened the latent period of erection in castrational rats after electric stimulus and the latent period of coitus in castrational mice,increased coitus times in castrational mice,increased the appearance rate of sperm suppository in copulated female mice. the acute toxicity tests showed that the half lethal dose(ld50) of weijian was 901.53 mg/kg and 319.60 mg/kg, the long-term toxicity tests showed that large dose of weijian slightly increased the level of glutamic pyruvic transaminase and decreased the glucose,triglyceride and cholesterol of blood, while had no effects on other biochemical factors.
结果: 伟剑能明显缩短去睾丸大鼠的电刺激阴茎勃起潜伏期,明显缩短去睾丸小鼠的性交潜伏期,并增加去睾丸小鼠的性交次数,增加交配后雌性小鼠的精栓出现率;急性毒性试验测得伟剑的口服半数致死量(ld50)为901.53 mg/kg,腹腔注射的ld50为319.60 mg/kg;长期毒性试验研究表明该药在大剂量时可轻度升高谷丙转氨酶,轻度降低血糖、总胆红素及胆固醇,而对其他血液生化指标无影响。
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They were fed with VA 400IU/kg and 6500IU/kg diets starting from 3 weeks before copulating respectively.
于孕前3周开始分别饲以含维生素A400IU/kg和6 500IU/kg的饲料喂养至处死。
- 推荐网络例句
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Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".
歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车,和一双合并为一移交&整个lotta爱&。
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This is Kate, and that's Erin.
这是凯特,那个是爱朗。
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Articulate the aims, objectives and key aspects of a strategic business plan.
明确的宗旨,目标和重点战略业务计划。