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Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时,蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数,说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环烯醚萜对外周和中枢5-HT含量的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It shows that Iridoids composition of Valeriana jatamansi Jones have inhibit function on gastrointestinal function of mice with reserpine.1.3 Effection of Iridoids composition of Valeriana jatamansi Jones on gastrointestinal function of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.model replicating method is chronic stress for 28 days.

说明蜘蛛香环烯醚萜可改善利血平导致的胃肠运动亢进。1.3蜘蛛香环烯醚萜对慢性应激所致IBS大鼠胃肠功能的作用方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环(来源:49ABC论文网www.abclunwen.com)烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Research on the Iridoids composition of Valeriana jatamansi Jones in the role of mechanism of action of rat model induced by chronic stress3.1 Effection of Iridoids composition of Valeriana jatamansi Jones on 5-HT and 5-HIAA in colon,serum and central of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

同时,蜘蛛香环烯醚萜可显著降低醋酸所致小鼠的扭体次数,说明其有良好的镇痛作用。3蜘蛛香环烯醚萜治疗肠易激综合征机理3.1蜘蛛香环烯醚萜对5-HT神经递质的影响3.1.1蜘蛛香环(来源:5bABd5C论文网www.abclunwen.com)烯醚萜对外周和中枢5-HT含量的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠结肠、血清和脑中5HT、5-HIAA的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组,除对照组外,其余各组进行慢性应激实验。

It may means that Iridoids composition of Valeriana jatamansi Jones doesn\'t regulate the TPH1 transcription expression.3.4 Effection of Iridoids composition of Valeriana jatamansi Jones on SP and VIP of IBS rats induced by chronic stressMethods:Animals were randomly divided into7 groups:normal group,model group, OSD group,FXT group and Iridoids composition of Valeriana jatamansi Jones groups in quantiy of 24.92mg/kg,12.46mg/kg,6.23mg/kg.

造模后,中枢5-HT呈现降低趋势,这可能是导致动物出现活动能力下降和兴趣缺失的原因之一,蜘蛛香环烯醚萜可以增加下丘脑、海马和杏仁核中5-HT含量,推断蜘蛛香环烯醚萜可通过干预中枢的5-HT通路来改善IBS精神症状。3.2蜘蛛香环烯醚萜对胃肠激素的影响目的:探讨蜘蛛香环烯醚萜对慢性应激所致IBS大鼠SP和VIP的影响方法:动物随机分为对照组、模型组、昂丹司琼组、氟西汀组、蜘蛛香环烯醚萜24.92mg/kg、12.46mg/kg、6.23mg/kg组。

Juglone of600μg/kg,300μg/kg and 150μg/kg had no significant impact on tumor growth.

但600μg/kg、300μg/kg和150μg/kg胡桃醌对肿瘤生长没有明显的影响(P均>0.05)。

Methods LYS polymaccharides were isolated from Millettia Pulcha Kurz vur,LaxiorZ.Wei.After the mice were treated P.O with LYS polymaccharides0.425g/kg,0.85g/kg,1.70g/kg for8days continually,the effects of the swimming time,resist anoxic time and resist heat time were investigated,theactivity of serum SOD and GSH-Px and the content of MDA were determined.

从龙眼参提取粗多糖,按0.425g/kg、0.85g/kg、1.70g/kg连续给小鼠灌胃8天,观察不同剂量对小鼠游泳时间、耐缺氧时间、耐高温时间及血清SOD、GSH-Px和MDA含量的影响。

Scanning electron microscopy showed that the spores were shrinking and collapsing, and the mycelium walls were ramified and nodulated under combined application of Na2SeO3 65.714mg/kg+LaCl3 53.002mg/kg. Furthermore the surface ornamentation of cystidia became fuzzy and disappearing, and some cystidia were disappearing and collapsing.

扫描电镜观察结果表明,与对照相比,中浓度硒镧配施(Na2SeO3 65.714mg/kg + LaCl3 53.002mg/kg)时,孢子由正常椭圆形变成全部萎缩,菌丝粗壮;囊状体在较低硒镧配施浓度(Na2SeO3 43.810mg/kg + LaCl3 35.335mg/kg)处理时表面纹饰模糊、消失,个别囊状体破裂,表面带有藤蔓状的组织。

Intervention Participants were randomly assigned to 1 of 4 groups: 102 to the nonexercise control group and 155 to the 4-kcal/kg, 104 to the 8-kcal/kg, and 103 to the 12-kcal/kg per week energy-expenditure groups for the 6-month intervention period.

处理:参与者随机分成四组:对照组为不运动组,102人;每周能量消耗4-kcal/kg的155人;每周能量消耗8-kcal/kg的104人和每周能量消耗12-kcal/kg的103人,分别进行为期6个月的干预期。

Interention Participants were randomly assigned to 1 of 4 groups: 102 to the nonexercise control group and 155 to the 4-kcal/kg, 104 to the 8-kcal/kg, and 103 to the 12-kcal/kg per week energy-expenditure groups for the 6-month interention period.

处理:参与者随机分成四组:对照组为不运动组,102人;每周能量消耗4-kcal/kg的155人;每周能量消耗8-kcal/kg的104人和每周能量消耗12-kcal/kg的103人,分别进行为期6个月的干预期。

Methods A total of 60 male rats were randomly assigned into normal group,model group,drug control group,low -dose(17.5 mg·kg-1),mid-dose (35.0 mg·kg-1) and high -dose QLS (70.0 mg·kg-1) groups,10 rats in each group. White cell count,lecithin corpuscle density in prostatic fluid,prostate weight and prostate index were observed respectively after acute rat models were made by injecting 1 % carrageenan in th e seminal vesicle of prostate gland notopodium.

Wistar大鼠按体重区组随机分组方法分为空白对照组、模型组、阳性对照组及QLS低(17.5 mg·kg-1)、中(35.0 mg·kg-1)、高剂量组(70.0 mg·kg-1),每组10只,分别于前列腺背叶的精囊腺注入1 %角叉菜胶生理盐水溶液,制作大鼠非细菌性前列腺炎模型,观察测定前列腺液中白细胞数和卵磷脂小体密度、前列腺重量、前列腺指数。

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