查询词典 jatrorrhizine

On the basis of all the experimental results and the molecular modelling study, it is considered that Jatrorrhizine and Berberine binds to the site I and site II mainly by hydrophobic interaction and there are hydrogen bond and electrostatic interactions.

荧光竞争实验以及分子对接研究表明药根碱和小檗碱的结合区域分别位于蛋白质的亚结构域ⅡA和亚结构域ⅢA中，主要通过疏水作用结合，但还包括静电作用力、氢键。

Objective To study the hypoglycemic activity of jatrorrhizine and compare the effects of Jat, berberine, Huanglian Decoction, and compounds-mimic prescription on blood glucose level in mice.

目的研究药根碱的降血糖作用，并比较Jat、小檗碱、黄连煎剂及模拟方对小鼠血糖水平的影响。

MethodsTo extract the alkaloids of Radix Tinospora with different solvents,reckon the ratio,determine Jatrorrhizine Hydrochloride and Palmation Hydrochloride by HPLC,taking this as the indexes,to ascertain the optimum extraction technology.

方法用不同极性的溶剂对金果榄进行提取，计算出膏率，采用高效液相色谱法测定金果榄中生物碱的含量，以此做为定量指标，确定最佳提取工艺。

Result: Glutin could make the absorption of jatrorrhizine, coptisine, berberine and total alkaloids increased by 30%. Tween 80 and arabic gum did not affect the absorption of berberine, but inhibit that of other alkaloids. There had no influence of lecithin on the absorption of alkaloids.

结果：明胶使药根碱、黄连碱、小檗碱和总生物碱的吸收均提高约30%；聚山梨醇酯和阿拉伯树胶对小檗碱的吸收无影响，而抑制其他3种生物碱和总碱的吸收；卵磷脂几乎不影响各生物碱的吸收。

Effects of temperature and mobile phase composition on the interaction betweenβ_2-AR and both of palmatine and jatrorrhizine.

3研究了温度及流动相组成对盐酸巴马汀和盐酸药根碱与β_2-AR之间相互作用的影响。

Chapter 2: The binding of Jatrorrhizine and Berberine with human serum albumin was investigated by spectroscopy and the molecular modelling study.

第二章：应用光谱法结合计算机模拟技术对人血清白蛋白与异喹啉类生物碱药根碱、小檗碱的相互作用进行了详细的研究。

The interaction of Jatrorrhizine and Berberine with serum albumin can induce the changes of secondary structure of serum albumin with reduction ofα-helices.

红外光谱和圆二色谱研究表明异喹啉类生物碱的加入引起人血清白蛋白二级结构的变化，降低了血清的α-螺旋结构含量。

Effect of jatrorrhizine, berberine, Huanglian Decoction and compound-mimic prescription on blood glucose in mice

药根碱、小檗碱、黄连煎剂及模拟方对小鼠血糖的影响。

Result: The contains of berberine, jatrorrhizine, palmatine in total alkaloids show a good pertinence with total alkaloids.

结果：总生物碱中的小檗碱等的量均与总生物碱呈较好的相关性。

These results indicated that palmatine had one common binding site on the immobilizedβ_2-AR column,the association constant was 2.93×10~4 L/mol at pH 7.2 and 25℃,while jatrorrhizine had two bingding sites,the association constants at these two sites were 1.93×10~4 and 1.56×10~5 L/mol,respectively.And the molar ratio of weak bingding sites to strong binding sites was 93:7.Palmatine and jatrorrhizine had competed for low-affinity site in immobilizedβ_2-AR.

结果表明，盐酸巴马汀与β_2-AR只有一类结合位点，在流动相pH 7.2，温度25℃时盐酸巴马汀与β_2-AR的结合常数为2.93×10~4 L/mol；盐酸药根碱与β_2-AR有两类结合位点，在这两类结合位点上的结合常数分别为1.93×10~4和1.56x10~5L/mol，两类结合位点数的比值为93：7，且盐酸巴马汀和盐酸药根碱竞争低亲和力的结合位点。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。