查询词典 isosterism
- 与 isosterism 相关的网络例句 [注:此内容来源于网络,仅供参考]
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They are of chemical and pharmacological interest due to their isosterism with indoles and azaindoles, two im-portant heterocycles involved in many alkaloids.
该类化合物由于其特定的生理活性以及和吲哚、氮杂吲哚等在结构上的类似性,引起了人们广泛的兴趣。
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Methods: According to the mechanism of cough reflex, the c-fibres's role in the respiratory system, and the principle of isosterism. Here, a peripheral antitussive LD was regarded as a lead compound. Amino functional groups, as substituents at the 1-hydroxy group of the racemate of LD, were introduced into the structure of the molecule. These novel compounds were confirmed by 1H-NMR, MS spectrum. Their antitussive activities were studied on mice in sequential method. The EDT50, the stimulating time that caused cough by NH3 on half of mice, were measured. Then could caculated the ratio R between the EDT50 of the treated groups and control group.
根据咳嗽反射的机制及C-纤维在呼吸系统的作用,以外周镇咳药左羟丙哌嗪为先导化合物,依据电子等排原理,在其结构中引入氨基以取代羟丙哌嗪分子中1位的羟基,设计一系列未见报道的化合物(01-15);并采用了一条适宜的路线进行合成,通过1H-NMR、MS确证结构;采用&序贯法&实验进行新化合物的镇咳活性研究,动物模型采用氨水引咳小鼠,获得引致半数小鼠咳嗽的氨水刺激时间(EDT50)及给药组EDT50与对照组的比值R。
- 推荐网络例句
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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.
每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。
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Maybe they'll disappear into a pothole.
也许他们将在壶穴里消失
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But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.
但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。