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isobutyryl相关的网络例句

查询词典 isobutyryl

与 isobutyryl 相关的网络例句 [注:此内容来源于网络,仅供参考]

A process for preparingp-fluo-2-(2-methyl-3-propionyl)-4-oxy-N,3-diphenyl-phenylbutylamide includes such steps as Friedle-Craft acylating of newly prepared phenylacetyl chloride and fluorobenzene under catalysis of AlCl3 to obtain 4-fluoro-phenylbenzyl ketone, brominating at carbonyl alpha position under catalysis of less AlCl3 to obtain alpha-bromo-4-fluo-phenylbenzyl ketone, and condensing with isobutyryl acetanilide under action of sodium ethoxide.

本发明涉及一种制备对氟-2-(2-甲基-3-氧丙基)-4-氧-N,3-二苯基-苯丁酰胺(1)的方法,其包括以下步骤:新制的苯乙酰氯与氟苯在AlCl3催化下进行Friedle-Craft酰化反应,得到对4-氟-苯基苄基酮(4);化合物(4)在少量AlCl3催化下进行羰基α位溴化,得到α-溴-4-氟-苯基苄基酮(5);然后(3)异丁酰乙酰苯胺在乙醇钠作用下与化合物(5)进行缩合。

The acyl derivatives all exhibited higher inhibitory effect than prinsepiol, among which isobutyryl and diacetate derivatives exhibited highest activity with EC50 of 3.85 mg/L and 5.60 mg/L respectively.

在Prinsepiol 4,4'位引入不同酰基后化合物的抑菌活性均有不同程度提高,其中4,4'-二异丁酰基衍生物和4,4'-二乙酰基衍生物的抑菌活性均较好,有效中浓度(EC50)分别为3.85和5.60 mg/L,是Prinsepiol的6~8倍。

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