查询词典 irritancy

The framework which accounts for the integration of environment, English teaching theories, emotion and teaching strategies contains four towers -language perception, language understanding processing, emotions, instructional strategies and three levels-response processing, conscious management and meta-management as well as five most related emotional variants-anxiety, irritancy, confidence, excitement and joyfulness.

框架构建的理论背景是心理学理论、基于设计的理论和教学理论。从心理学视角阐述当今的情感模型和心理语言学理论，从基于设计的视角讨论认知情感架构，从二语习得Krashen情感过滤假说视角研究英语教学中的情感处理。

Results The tiopronin in situ gel of 0.2 % sodium hyaluronate had proper gelating temperature and certain sustained releasing ability, Papp and retention time of which was 15.43 cm·s-1 and 130 min respectively, irritancy and stability were up to standard of ophthalmic preparation.

结果 含有质量分数0.2 %透明质酸钠的硫普罗宁原位凝胶具有适宜的胶凝温度和一定的缓释作用，其角膜表观透过系数为15.43 cm·s-1，角膜前滞留时间为130 min；刺激性、稳定性符合眼用制剂要求。

Methods The formula of tiopronin in situ gel was designed and optimized by determining the gelating temperature, gel dissolving and drug releasing, transcorneal penetration in vitro, and was evaluated by investigating retention time, irritancy and stability.

以胶凝温度、凝胶溶蚀量、体外药物释放度、离体角膜透过性为考察指标，设计和优化处方；以家兔为受试动物，考察硫普罗宁在角膜的滞留时间、刺激性及稳定性。

Results Acute oral LD50 were 278 mg/kg and 56.2 mg/kg in rats and mice respectively, while dermal LD50＞2 000 mg/kg and inhalative LC50＞3 000 mg/m3. Skin and eye irritancy were estimated to be negative and mild respectively. Cumulative coefficient was 2.3 and allergic rate was 0%. A negative result was observed in Ames assay while increased frequencies of bone marrow micronuclei and spermatocyte chromosome aberrations were noted in the high dose (11.24 mg/kg) group.

结果 大小鼠急性LD50分别为278 mg/kg和56.2 mg/kg；大鼠经皮LD50＞2 000 mg/kg；急性吸入LC50＞3 000 mg/m3；无皮肤刺激性，轻度眼刺激性；蓄积系数2.3；致敏率为0；Ames试验结果阴性；微核和染色体在高剂量组(11.24 mg/kg)与阴性对照组相比有高度显著性差异(P＜0.01)；大鼠90天亚慢性经口的最大无作用剂量为2.825 mg/kg。

All enhancers did not significantly change the transcorneal lag time of ENX. The irritancy of poloxamer and Azone was observed.? The results of in vitro release studies showed that the ENX gel based 3% HPMC K4M and 3%HPMC F4M povided sustained release of the drug over an 8-h period in vitro.Diffusion area has significantly effect on drug release, and pH value of medium and rotation rate have effcet on drug release.However, the diffusion shield has no effect on drug release. The P_ value of the preparation based on 3% HPMC F4M was 1.34-fold of conventional eye drops of ENX.

体外溶出度试验结果表明，以3％的HPMC K4M和F4M为基质制备的ENX凝胶剂的体外释放行为符合眼用缓释制剂的要求；体外释放度影响因素试验结果表明，释放面积对释放度有显著性影响，pH值和转速略有影响，而扩散屏障没有影响；离体角膜透过实验结果表明，以F4M为基质制备的凝胶剂中ENX的表观渗透系数P_(app是对照组的1.34倍，说明F4M与眼角膜的相容性较好，是一种理想的眼用制剂增稠剂，可以在眼用制剂中广泛采用。

I don't know what "home" is, but I know it dispels irritancy and unhappiness.

&家&是什么，我不知道；但烦闷———忧愁，都在此中融化消灭。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。