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Three categories of cytokines, including Th1/Th2 cytokines, chemokines and adipocytokines, are involved in the physiopathological process of NASH. In order to elucidate the significances of cytokines in the pathogenesis, serological diagnosis, and treatment efficacy evaluation of HASH, we reviewed the documents on the relationship between cytokines and non-alcoholic steatohepatitis.
参与NASH病理生理过程的细胞因子归纳起来有3类,即Th1、Th2细胞因子和趋化因子及脂肪细胞因子,本文了回顾3类细胞因子与NASH发生、发展关系的最新研究进展,从而阐明细胞因子在NASH发病机制、血清学诊断和治疗效果评价等方面的意义。
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This conclusion is based on three groups of experiments with detached root tips of wheat seedlings: By following the time course changes of NO synthase , superoxide synthase and ABA accumulation under dehydration stress, we found that ABA accumulation was preceeded by the changes of NOS and superoxide synthase. ABA accumulation induced by dehydtrion stress and osmotic stress can be blocked by NO scanvegers and NOS inhibitors, while only dehydration stress-induced ABA accumulation can be blocked by ROS scanvegers. Exogenous applied NO or ROS induced ABA accumulation in root tips of wheat seedlings, and synergistic effects were found between NO and NO. The in planta expereiments also proved that ROS and NO are involved in water stress-induced ABA accumulation.Ⅱ.
证据主要来自以离体根尖为材料的实验:(1)通过检测干旱胁迫下小麦根尖NOS活性、O〓合成酶活性和ABA积累的时间变化进程,发现ABA积累滞后于ROS和NO的变化;(2)抑制剂实验表明,NO清除剂和NOS抑制剂可以抑制自然干旱胁迫及渗透胁迫诱导的小麦根尖ABA积累,ROS清除剂抑制自然干旱胁迫诱导的ABA积累而不抑制渗透胁迫诱导的小麦根尖ABA积累;(3)在非胁迫条件下施加外源的ROS或NO可以诱导小麦根尖积累ABA,ROS和NO之间具有协同作用。
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It is the main point to focus on the elucidating of the pathogenesis of PNC as a polygenetic inheritance tumor, primarily establishing of the concept of susceptibility gene groups in NPC and the carcinogenesis model of the multi-step Domino effect involved in the molecular mechanisms of NPC dominated by susceptibility gene groups in order to lay out a substantial foundation for finding the high-risk susceptibility factors of NPC, screening the high-risk population of NPC and exploring the targetic and individual measures in diagnosis and treatment of NPC.
现主要阐述鼻咽癌作为一种多基因遗传性肿瘤的病因发病机制,初步建立鼻咽癌易感基因群的概念和鼻咽癌发生发展过程中易感基因群主导的多阶段性多米诺骨牌效应分子机制假说,为寻找鼻咽癌遗传易感风险因子,筛选鼻咽癌高危人群以及探索鼻咽癌靶向性及个体化的诊断和治疗手段奠定实验与理论基础。
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In situ hybridization and immunocytochemical studies indicated that treatment with 17beta -estradiol increased the number of aromatase-immunoreactive cells and their immunoreactivities, especially in the preoptic area of the hypothalamus, where the density of the aromatase-immunoreactive cells was 2.6 folds higher than the control group. Results indicated that brain aromatase may be involved in the feminization induced by 17beta -estradiol of the grey mullet.
原位杂交和免疫细胞化学定位表明:雌二醇处理组鲻鱼脑内芳香化酶阳性细胞数量和反应强度均提高,尤其在下丘脑视前区,芳香化酶阳性细胞的分布密度为对照组的2.6倍,说明17beta-雌二醇诱导幼鲻雌性化可能与脑芳香化酶的表达有关。
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It has been successfully applied in the fields of high-performance carbon fiber, needle coke used for ultrahigh power electrode, anode of rechargeable lithium-ion batteries, activated carbon with super-high surface area, catalyst supports and carbon foams、 In this paper, the effects of raw materials and pyrolysis conditions including heat-treatment temperature, pressure and time on the formation and development of carbonaceous mesophase were discussed in detail Since complex constitutes of raw material, various reactions and phases are involved in the process of mesophase evolution, we suggest that a given carbonaceous mesophase product should be manufactured by selecting raw materials and setting pyrocondensation conditions according to the specific requirement of the product, so that products with the best structure and performance could be obtained.
它在高性能炭纤维、超高功率电极用针状焦、锉离子二次电池负极、超高比表面积活性炭及催化剂载体、泡沫炭等领域得到了较好的应用。综述了原料和热缩聚条件对炭质中间相形成和发展的影响,这些影响因素包括原料的种类、热缩聚温度、反应压力和保温时间等。通过讨论指出,由于炭质中间相涉及的原料种类多样,热缩聚制备过程中涉及的反应、物相复杂,因此,在制备特定性能的产品时,应针对产品的特定性能要求来选择原料、设定热缩聚条件,以制得具有最佳结构和性能的产品。
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In conclusion, the hepatotoxicity of clivorine is caused by the hepatotoxic pyrrolic metabolites formed in vivo. CYP3A involved in the formation of pyrrolic metabolites and plays a key role in metabolism-induced hepatotoxicity of clivorine.
Clivorine的肝毒性是其在体内形成的肝毒性吡咯代谢物所致,CYP3A参与了肝毒性吡咯代谢物的形成并在clivorine的代谢致毒方面发挥了关键性的作用,因此CYP3A的诱导剂和抑制剂可以影响肝毒性吡咯代谢物的形成,从而影响clivorine的肝毒性。
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Methods:Six cases of large intestinal diffuse cavernous hemangiomas were surgically treated from 1994 to 2005, with whole Colorectal involved in 1 case, rectosigmoid colon in 4 cases, rectum in 1 case.
1994年至2005年手术治疗6例,其中全结直肠弥漫性海绵状血管瘤1例,直肠乙状结肠弥漫性海绵状血管瘤4例,直肠弥漫性海绵状血管瘤1例。
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Carbon source,nitrogen source,cultivation temperature,the initial pH of the culture medium,the speed of shaker are involved in the experiments,and the evaluation of retting is based on the residual gum content in retted flax roving.Then flax roving treated under the optimal conditions is compared with untreated roving in ingredient analysis,scanning electron microscope and infrared spectrum analysis.The result shows that the microbe treat...
用筛选出的一种真菌对亚麻粗纱生物处理的工艺进行了探讨,以残胶率作为评定标准,研究了碳源、氮源、温度、pH值、摇床转速对亚麻粗纱生物处理效果的影响,并在最佳工艺下对亚麻粗纱再处理,对处理后的粗纱进行成分分析、扫描电镜、红外光谱等测试,结果表明:亚麻粗纱的生物处理是可行的。
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In my new-found home in Taiwan, the camaraderie of Team Cinelli Ritchey has been an inspiration for me to be involved in racing again, and share my experiences with younger riders pursuing this amazing sport.
在我的新故乡台湾,Team Cinelli Ritchey 自行车队的团队精神重新激励我参加赛事,也给我动力和年轻人分享我在这个 amazing 运动的经验。
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The world known company METRO has been affected by the charm of Sud de France, they will be completely involved in the Festival and hold a wine tasting in associate with la Maison du Langudedoc Roussillon. 25 specialist will be invited in this wine tasting and they are going to taste the good wines from the Mediterranean.
全球500强企业麦德龙也感受到了来自法国南部的超强感染力,他们不仅将全力加入到此次美食节活动中,还将与朗格多克-鲁西荣之家联合举办一场品酒会,届时将邀请25位专业人士参加,品尝到来自地中海沿岸的荣耀葡萄酒。
- 推荐网络例句
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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.
从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。
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The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.
集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐
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The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.
血精的原因很,以良性病变为主。