查询词典 intima

The intima and adventitia edge detection of IVUS images has great significance in the diagnosis and treatment of the coronary artery disease.

IVUS图像内、外膜边缘的提取在冠状动脉疾病的诊断和治疗上有着重要的意义。

Results:Distribution of mast cells in study group was that minority mast cells were observed in the intima and media, but the more were observed to gather in the adventitia.

结果：研究组肥大细胞的分布，内膜或中膜均可见少数肥大细胞，外膜则较多聚集。

Experimental methods: pathological slices: To observe the changes of pathomorphology and measure the circular area of internal elastic lamina , area of neonate intima and vascular lumen, the intimal proliferatory index and percentage, the index of lumen stenosis and positive index of proliferating cell nuclear antigen through the specimens stained by HE and immunohistochemistry.

实验方法：病理切片：进行HE染色和免疫组织化学染色，分别观察病理形态学改变；测定和计算受损血管内弹力膜环绕总面积、新生内膜面积、管腔面积、内膜增生指数、内膜增生百分比、管腔狭窄指数和增殖细胞核抗原阳性指数；观察MMP-2、MMP-3、TIMP-1和PDGF-BB的免疫组化表达。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

Hybridization of cDNA probe and gene chip was carried out, gene chip was scanned with Scan Array3000, and results were analyzed with ImaGene 3. 0. Result: 1 Toluidine blue staining of semithin section showed: compared with control group, the boundary of tunica intima, tunica media and tunica adventitia was not distinct, tunica intima and internal elastic membrane was thickened and multilaminar.

将标记了荧光素的cDNA与细胞周期相关基因表达谱芯片杂交，扫描并分析杂交结果。cy5/cy3 ratio值在0.5～2.O之外且一对Double基因表达趋势一致的基因为表达有差异基因，ratio值＞2.O表明DM组该基因上调，ratio值＜0.5表明DM组该基因下调。

Result: The divided functional recipes of DHZCP could significantly decreased the deposit of lipid and the atherosclerotic plaque area in aorta intima, relieve the histopathological changes of atherosclerosis,and inhibited the proliferation of vascular smooth muscle cells and collagen to reduce pachynsis of vascular intima. The divided functional recipes of DHZCP also reduced IT, IMT and IT/MT and reversed the contractive vascular remodeling.

结果：大黄虫丸各功效组分均能减少家兔主动脉内膜脂质沉积，使AS斑块面积减小（ P 。05）；抑制血管平滑肌细胞增殖和胶原纤维增生，减轻内膜增厚；降低IT，IMT，IT/IMT比值（ P 。05），干预收缩性血管重塑；减轻线粒体肿胀，减少泡沫样细胞形成。

Results①The tunica intima and tunica media of the BVs were thin, the tunica adventitia was thick. No complete layer of smooth muscle was found in the tunica intima, the SMC with single elliptical or rod-shape nuclear, fusiform in shape and different in length, ran longitudinally and distributed unequally in the wall of BVs, intercrossed with each other, endothenial cell wasn't covered fully sometimes.

中膜未见完整平滑肌层，SMC呈梭形，大多呈纵切面，有的呈斜切面，不均匀地分布于管壁中；平滑肌纤维长短不一，相互交错排列，有时并不完全覆盖内皮细胞，细胞核单个，椭圆形或长杆状。

Morphological changes of abdominal aorta: The aorta intima was smooth and endothelium cells were continuous with small intervals between cells in blank control group,endothelium cells presented normal configuration without edema;while intima in model control group became thick and upheaved, part of endothelinm cells detached with widened intervals.

腹主动脉形态学变化观察结果，可见空白组腹主动脉内膜表面光滑，内皮细胞连续，细胞间隙较小，内皮细胞无水肿，形态正常；模型对照组腹主动脉内膜增厚、隆起，血管内皮细胞可见部分脱落，细胞间隙增宽，内皮细胞有水肿。

Results The body weight, visceral fat and body weight ration, as well as the levels of blood glucose, insulin, triglyceride, total cholesterol, LDL, and total FFA, were significantly lower in high fat-fed group than in control group (P.01). The aortic tunica intima was intact, the number of foam cells was decreased, and inflammatory cells infiltrated into the med-intima smooth muscle of the n-3 PUFA group. However, with no such changes were observed in control and n-3 PUFAs groups.

结果 n-3脂肪酸组大鼠体重第1~11周均明显降低，空腹血糖、血清胰岛素、TG、TC、LDL-C、总FFA和内脏脂肪占体重百分比均明显低于HF组，HDL-C则明显高于HF组，与对照组无明显差别；n-3脂肪酸组大鼠主动脉主动脉内膜完整无内皮细胞脱落现象，内膜下泡沫细胞及炎细胞浸润减少，内膜的NF-κB呈弱阳性表达，IκBα呈阳性表达，ICAM-1和MCP-1均呈阴性或弱阳性表达。

The aortic tunica intima was intact, the number of foam cells was decreased, and inflammatory cells infiltrated into the med-intima smooth muscle of the n-3 PUFA group. However, with no such changes were observed in control and n-3 PUFAs groups. Little or no expression of NF-κB, ICAM-1 and MCP-1, and a high expression level of IκBα were detected in aortic tunica intima of the n-3 PUFA and control groups, while high expression levels of NF-κB, ICAM-1 and MCP-1, and little expression of IκBα were detected in aortic tunica intima of the high fat-fed group.

结果 n-3脂肪酸组大鼠体重第1~11周均明显降低，空腹血糖、血清胰岛素、TG、TC、LDL-C、总FFA和内脏脂肪占体重百分比均明显低于HF组，HDL-C则明显高于HF组，与对照组无明显差别；n-3脂肪酸组大鼠主动脉主动脉内膜完整无内皮细胞脱落现象，内膜下泡沫细胞及炎细胞浸润减少，内膜的NF-κB呈弱阳性表达，IκBα呈阳性表达，ICAM-1和MCP-1均呈阴性或弱阳性表达。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。