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WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.

WD40域，在真核蛋白质的数量发现，涵盖了包括各种功能适配器/信号转导，mRNA前体细胞骨架组装加工和管理模式；通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长，因此得名WD40；之间的生长激素和WD是一个保守的核心，作为一个稳定的螺旋桨式平台，可以绑定的蛋白可以稳定或可逆性；形式与每个刀片是一个四叶片组成的几个类似结构的螺旋桨，搁浅反平行β-负债表；很少检测副本实例假设，形成了聚大结构，每个WD40重复序列形成了前三个链的一个刀片，并在未来的刀片上链，最后C -末端WD40重复完成了第一WD40重复叶片结构，创造螺旋桨的封闭环结构，对螺旋桨顶部和底部表面残留物，则建议协调与其他蛋白质和/或小配体； 7重复副本存在于相互作用这条路。

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are propos

WD40域，在真核蛋白质的数量发现，涵盖了包括各种功能适配器/信号转导，mRNA前体细胞骨架组装加工和管理模式；通常包含一个从11月24日生长激素肽的N残留端和西部数据肽在其C端和40残留长，因而得名WD40；介于生长激素和WD一个保守的核心，作为一个稳定的螺旋桨式平台，可以绑定的蛋白可以稳定或可逆，形成了一个螺旋桨式与每个刀片是一个四叶片结构组成若干链反平行的β-片；与数份检测实例假设，形成了聚大结构，每个WD40重复序列形成了前三个一个刀片和绞线的最后在未来的刀片链，最后C -末端WD40重复完成了第一WD40重复叶片结构，创造螺旋桨的封闭环结构，对螺旋桨顶部和底部表面残留的建议，配合和其他蛋白质的相互作用/或小配体； 7重复副本，目前这条路。

New Instances:The Caverns of Time: Old Shattrath. In this 50 man raid instance you will defend Granny Smith the Fruit Vendor fro m Cro Threadstrong and his army in order to prevent the events leading to the 4th Great War.

新的副本：时光之穴——沙塔斯在这个50人raid副本里，你将协助史密斯奶奶抵抗来自制皮商兽人和他的军团的袭击，成功抵御这次入侵事关重大，它将阻止第四次魔兽战争的发生。

These are instances of unnecessary work, for there is no real need for gharries and rickshaws; they only exist because Orientals consider it vulgar to walk.

这些都是不必要工作的例子，因为并非真正需要马车和人力车，它们之所以存在，全是因为东方人认为走路没派头。

And his favourite passages in history are the bits where believers spoke truth to power, not the instances when pliant greybeards did favours to the sultan.

另外，他所喜爱的历史事件是信徒们（往往是勇敢的苏菲派神秘主义者）向权力说真话的点点滴滴，而不是顺从的老人们偏向于苏丹的那些事例。

Multiples instances can be grouped to synchronize the keyboard of one instance of a group to drive all players in the group at the same time.

多个场景可以被组织在一起以便同步一组当中一个场景的键盘，以便同时指挥一组当中所有的演奏者。

In many instances his hearers had not asked him whence he came or whither he went.

往往听他讲道的人没有问他从哪里来，往哪里去。

He explained that this name was part of the title of a silly fairy tale, called The Three Princes of Serendip: as their highnesses traveled, they were always making discoveries, by accidents and sagacity, of things which they were not in quest of ... One of the most remarkable instances of this accidental sagacity (for you must observe that no discovery of a thing you are looking for, comes under this description) was of my Lord Shaftsbury , who happening to dine at Lord Chancellor Clarendon's , found out the marriage of the Duke of York and Mrs. Hyde , by the respect with which her mother treated her at table.

他解释说这个名字是&一个朴素的神话故事，称作 The Three Princes of Serendip的童话&的名字的一部分：当这些殿下旅行时，他们总是通过意外和精明地发现他们并没有寻求的东西…这种 accidental sagacity的最著名的实例你必须注意到根据这种描述你没有发现你正在寻找的东西）是我的沙夫茨伯里老爷，偶然在钱塞勒·克拉伦登老爷处用餐时，发现了约克的杜克同海德夫人的婚事是根据她的母亲在吃饭款待她时发现的。

He jotted down instances that he came across.

他把看到的例子记下来。

Do not fail to observe the class of sins prominent in these instances, especially the two last-named, and their relationship to "lasciviousness" already spoken of.

不遵守课堂的罪孽突出在这些情况下，尤其是最后两个命名，他们的关系& lasciviousness &已经谈过的。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。