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The 20S catalytic core of the 26S proteasome has the shape of a barrel made of four rings which are composed of seven differentαsubunitsα_1-α_7 at two outer rings and seven differentβsubunitsβ_1-β_7 at two inner rings at which the catalytic sites locate. Three of theβsubunits contain proteolyses sites, which are sequestered in the hollow interior of the 20S particle. Substrates enter the 20S through a narrow channel formed by theβsubunits, whose N-termini, depending on their conformation, can either obstruct or allow substrate entry and thus function as a gate. This entry channel is narrow and only permits passage of unfolded, linearized polypeptides.

哺乳动物26S蛋白酶体是由一个20S催化颗粒(catalytic particle，CP)和两个19S调节颗粒(regulatory particle，RP)组成的ATP(adenosine-triphosphate，ATP)依赖性蛋白水解酶复合体。20S CP是26S蛋白酶体的催化核心，它是由4个圆环堆叠形成的桶状复合物，其中两侧外环每个环是由α_1-α_7亚基组成，两个内环每个环是由β_1-β_7亚基组成，4个环的中央形成一个狭窄的内腔。2个β内环形成了20S CP的催化中心空腔，其内壁为催化活性位点所在地；外侧α环中心的孔道是底物到达催化中心空腔的通道，一般被α亚基上的N末端所封闭，阻止胞内非目的靶蛋白进入20S CP内被降解破坏。

Barton: I''ve always found that writing comes from a great inner pain.

巴顿：我一直认为写作来源于内心的巨大痛苦。

The inner logistics is an important basic point to enterprise operation and management.

企业内部物流是企业生产经营活动的基础环节之一。

In the "Canton construction" Tenth Five-Year "plan", the urban construction is expected to invest 80 billion yuan to inner ring, outer ring as the basic line, adjusting the function of the layout of urban areas, in urban centers delegation to Baiyun Mountain and Pearl River started at the core of urban design and landscape construction, and give full play to the Canton of Physical Geography and historical and cultural advantages, Castle Peak, clear water and the history and culture of Guangzhou organically integrated into the overall urban environment, the formation of Baiyun Mountain as the center, the old and new cities north-south axis, the Pearl River with the east-west tourism landscape of the urban landscape architecture.

在"广东建设"十五"计划"，城市建设，预计投资八百点〇〇〇亿元以内环，外环的基本路线，调整功能布局，城市地区，在城市中心代表团以白云山和珠江开始为核心的城市设计和景观建设，并充分发挥广东自然地理和历史文化优势，青山，清澈的海水和纯净的历史和文化有机地融入广州的整体城市环境，形成白云山为中心，新老城市的南北轴，珠江三角洲与东西旅游景观的城市景观设计。

In the "Canton construction" Tenth Five-Year "plan", the urban construction is expected to invest 80 billion yuan to inner ring, outer ring as the basic line, adjusting the function of urban layout, in the city center group, to Baiyun Mountain and Pearl River started at the core of urban design and landscape construction, and give full play to the Canton of Physical Geography and historical and cultural advantages, Castle Peak, clear water and the history and culture of Guangzhou organically integrated into the overall urban environment, the formation Baiyunshan as the center, the new , the old north-south axis of the city, the Pearl River with the east-west tourism landscape of the urban landscape architecture.

在"广东建设"十五"计划"，城市建设，预计投资八百点零零零亿元以内环，外环的基本路线，调整城市功能布局，城市中心组，以白云山和珠江开始为核心的城市设计和景观建设，并充分发挥广东自然地理和历史文化优势，青山，清澈的海水和纯净的历史和文化有机地结合到广州城市总体环境，形成白云山为中心，新的，旧的南北轴线的城市，珠江三角洲与东西方的旅游景观的城市景观设计。

It includes bore/outerside diameter deviation from basic, inner ring/outer ring width deviation in single radial plane.

几何精度包括内径偏差、平均内径差、外径偏差、平均外径差、套圈端面平行差的允许值。

Trama The inner tissue of the gills in basidiomycete fungi that is made up of loosely packed hyphae.

菌髓：在担子菌的由多条菌丝松散围绕形成的菌褶内部存在的组织。

The lake water became a part of pore water in the sediment and is gradually evolved into modern shallow groundwater, which is the main supply water for residents'living.2. Chemical characteristics of high As groundwater have been evaluated. Arsenic concentrations in shallow groundwaters from the Hetao Basin of Inner Mongolia range between 0.6 and 572μg/L.

湖泊在消亡过程中，高度浓缩的富含砷的湖水被埋藏、保存到沉积物的空隙中，成为区域地下水的一部分，经长期演化形成了今天的高砷水，也是当地居民的取水层位。2。

After several months near the base of the plateau called "Home Plate" in the inner basin of the Columbia Hills range inside Gusev Crater

这个高原叫"本垒板"，位于Gusev Crater 的哥伦比亚山脉内部的大盆地里。在接近那个的高原的底部几个月之后

The pull-on disposable wearing article is provided with a chassis (15) and an absorbent batt structure (16) extending on the inner side.

该短裤式一次性穿用物品包含底盘(15)、和在其内侧延伸的吸收性棉胎结构体(16)。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。