查询词典 initiate

The regulation of gene expression is to have relations to the assembly of the DNA binding proteins which bind to DNA to initiate the transcription. Some of these proteins have the ability to promote bending or looping of DNA. The FIS protein regulates gene expression in Escherichia coli by this property of bending DNA. There are many researches to discover the mechanism of FIS protein binds to DNA. However the experiment data only show the supposititious results and figure out the model of FIS-DNA complex structure. This research uses molecular dynamics simulation to compute the detail of the interaction between FIS and DNA. We observed FIS prominently affects the DNA bending by the type of local bending. Analyzing the DNA structure properties, roll and slide, also demonstrates the local bending type and region. The hydrogen bonds between FIS and DNA are analyzed to compare with the experiment data. Finally we compute the binding free energy between FIS and DNA to estimate the result of simulation and compare with the value of λ-repressor-DNA complex.

基因的表现与结合於DNA促使DNA转录作用起始的DNA结合蛋白组装有关，一些这类的蛋白质具有促使DNA扭曲或将DNA形成环状的能力，FIS蛋白质即是藉由扭曲DNA的特性调控大肠杆菌基因的表现，目前已有很多的研究发现FIS与DNA结合的机转，然而这些实验的数据仅能显示推测性的结果，进而利用这些结果推论出FIS与DNA聚合体结构的模型，本研究利用分子动态模拟的方式计算FIS与DNA交互作用的细节，我们观察到FIS主要影响DNA的扭曲方式为DNA区域扭曲的类型，并且分析DNA结构特性roll与slide也指出扭曲方式为区域扭曲与其扭曲的区域，我们也分析FIS与DNA之间的氢键，并且与实验的资料作比较，最后我们计算FIS与DNA之间的结合自由能评估模拟的结果，并且计算出的值和λ-repressor与DNA聚合体结构的实验值作比较。

In the teen-ager period,students' physiology and psychology are in rapid change and development,which is imbalanced and liable to initiate contradictory reflections one after another.

青少年时期的生理和心理均处于急骤的发展变化中，但这种发展又是不平衡的，从而引发了一系列矛盾反映。

A control which may be used to initiate a command in an application or to toggle an application state.

一个可以在应用程序中触发一个命令或确定应用程序状态的控件。

On how polar bear moms subtley initiate their young into the rights of predation through tomfoolery.

北极熊母亲是如何通过愚蠢的举动巧妙地让幼仔学会捕食的。

On how polar bear moms subtly initiate their young into the rights of predation through tomfoolery.

北极熊母亲是如何通过愚蠢的举动巧妙地让幼仔学会捕食的。

Hellip;on how polar bear moms subtly initiate their young into the rights of predation through tomfoolery.

hellip；北极熊母亲是如何通过愚蠢的举动巧妙地让幼仔学会捕食的。

An input trigger can be used to close an individual channel or to initiate a scan of several channels.

输入触发可被用来闭合某个通道，或启动几个通道的一次扫描。

When either of these relays operates to initiate tripping of the line breaker, it also energizes a timer to start the breaker backup function.

当其中任何一个继电器开始断开断路器的时候，它也开启一个断路器定时器的后备功能。

At this stage the nage allows the uke to initiate an attack and he receives it by using his movement to blend with the attack.

在这个阶段，取方让受方发动攻击，然后他接招并且使用他的移动来化解对手的攻击。

The difference between this stage and the last is that in the last stage the nage allowed uke to initiate and then he led the "attention" of the uke via his own movement.

这个阶段跟上一个阶段的差异在於取方在上一阶段让受方可以发动攻击，然后才用自己的动作来引导受方。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。