查询词典 inhibits

Abrin is one of the potent toxins isolated from the beans of plant abrus precatorius.the toxic protein consists of two disulfide-bonded subunits,the a and b chains.the b chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.after entering the cells,the a chain catalytically inactivates 60s ribosomal subunits by removing adenine position 4324 of 28s r–rna,and thereby inhibits protein biosynthesis.

相思子毒素是从豆科植物(abrus precatorius l。)种子中分离的一种细胞毒性蛋白。它由a，b两条链组成，由一个二硫键相联，b链具有半乳糖凝集活性，可与细胞膜上受体结合，帮助a链进入细胞内，a链进入细胞催化失活60s核糖体亚基，从而使细胞蛋白合成被抑制。

The ester of salicylic acid and acetic acid, it inhibits production of prostaglandins in the body.

系水杨酸和醋酸的酯，会抑制前列腺素的生成。

One, called TSA, inhibits the enzyme that removes acetyl groups.

一个是TSA，它可以抑制去除乙酰基的酶。

This can be contrasted with Lupus anticoagulant which inhibits agglutination in the presence of thrombin.

这可对比性狼疮抗凝抑制凝集，在场的凝血酶。

Modified with SiO2 inhibits the hydrogen transfer reactions and formation of aromatics in liquid product.

SiO2的修饰抑制了氢转移反应及液体产物中芳烃的生成。

This drug inhibits the action of carbonic anhydrase on the proximal convoluted tubules within the kidneys, which effectively inhibits reabsorption of bicarbonate, thus alkalinizing the urine.

这种药能抑制肾里面靠近环绕形小管碳的脱水酶作用，而这种作用抑制重碳酸盐的重吸收，因而碱化尿。

131I-AS inhibits proliferation of endothelial cells in vitro and inhibits LLC growth in vivo and it outdoes AS or 131I alone.

131I-AS在体外能明显抑制内皮细胞的生长，在体内能明显抑制小鼠Lewis肺癌移植瘤的生长，其抑制作用强于单纯的等浓度的AS和131I。

Itric oxide inhibits the expression of adhesion molecules, and thus inhibits the expression of monocycles and platelet.

O还能抑制黏附分子的表达，进而抑制单核细胞、血小板的表达及内皮素－1的产生。

1、Cur inhibits K562 cells growth and induces cell apoptosis may be correlated with the down-regulation of p210~、inhibition of protein tyrosine phosphorylation and the signaling molecules such as p-Erk1/2、c-myc which are relevant with cell growth and apoptosis; 2、Cur synergizes STI571 to inhibit K562 cell growth and induce cell apoptosis may be correlated with the down-regulation of p210~、inhibition of protein tyrosine phosphorylation and the signaling molecules such as Hsp90、PKC which are relevant with cell growth and apoptosis; 3、Cur reverses the resistance of K562/G01 cells to STI571, and synergizes STI571 to inhibit K562/G01 cell growth and induce cell apoptosis; 4、Cur inhibits human originated CML CD34~+ cell growth、induces cell apoptosis, and enhances STI571 to down-regulate the expression of p210~, finally inhibit cell growth and induce cell apoptosis.

从以上实验结果我们得出如下结论： 1、Cur抑制K562细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制下游p-Erk1/2、c-myc等信号分子有关； 2、Cur协同STI571抑制K562细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制Hsp90和下游PKC等信号分子有关； 3、Cur可逆转K562/G01细胞对STI571的耐药性，并与STI571协同抑制K562/G01细胞增殖和诱导凋亡，其抑制K562/G01细胞增殖、诱导细胞凋亡的作用可能与其下调p210~、蛋白酪氨酸磷酸化水平以及抑制下游Procaspase-3和NF-κB等信号分子有关； 4、Cur可抑制来源于CML患者骨髓的CD34~+细胞的增殖并诱导其凋亡，还可协同STI571下调CML CD34~+细胞p210~表达，进而协同抑制细胞增殖、诱导细胞凋亡。

Meanwhile,HDAC1 acetylation level is significantly increased.The overexpression of HDAC1 can promote erythroid cell proliferation and inhibits induced differentiation,the knockdown of HDAC1 or 2 inhibits erythroid cell proliferation and promotes induced differentiation.We also found that HDAC1 affects GATA1 mediated transcription activity.Thus our data revealed that HDAC1 may negatively regulate GATA1 mediated transcription and suggest that the dynamic regulation of GATA1 associated NuRD/MeCP1/HDAC1/HDAC2 complex may determine the onset of erythroid differentiation programs.Moreover,this study will eventually help to design new therapeutic approaches in treatment of leukemia.

研究发现在被诱导分化的小鼠红细胞白血病细胞中与GATA1相结合的HDAC1被乙酰化并失去活性，在血细胞中过表达HDAC1能够促进血细胞的增殖并抑制分化，反之在血细胞中敲除HDAC1或HDAC2能抑制血红细胞的增殖并促进分化，而且HDAC1能够负调控GATA1的转录活性，GATA1与NuRD/MeCP1复合体之间的动态调控，决定血红细胞分化的发生和发展，并为探索白血病的致病机理奠定了理论基础。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。