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The preliminary bioassary showed that at the concentration of 100μg/mL, the inhibitory rate of compounds Ⅴc to Fusarium graminearum was 81.3%;Ⅳe to Fusarium oxysporium was 83.4%;Ⅴe and Ⅴf to Cercospora sorghi were 79.7% and 72.4% respectively;Ⅳd to Fusarium graminearum and Fusarium oxysporium were 68.9% and 65.7% respectively.

初步生物测试结果表明：在质量浓度为100μgmL下，化合物Ⅴc对小麦赤霉病菌的抑制率达到了81.3%；化合物Ⅳe对马铃薯干腐病菌的抑制率达到了83.4%；化合物Ⅴe，Ⅴf对玉米弯孢病菌的抑制率也分别达到了79.7%和72.4%；化合物Ⅳd对小麦赤霉病菌和马铃薯干腐病菌的抑制率分别达到了68.9%和65.7%。

Objective:To observe the effect of Zhongfeng Xinglou TongFu Capsule on the balance of excitatory amino acid and inhibitory amino acid in cerebric tissues of rats with acute cerebral ischemic.

目的 观察中风星蒌通腑胶囊对急性脑缺血大鼠脑组织中氨基酸平衡的影响。

ObjectiveTo evaluate the inhibitory effect of different extracts from Cestrum nocturnum Linn..

目的探讨夜香树不同提取物对小鼠白血病细胞株L1210细胞的增殖抑制作用及机制。

Thunberg Fritillary Bulb is one of the most popular Traditional Chinese herbs. Some trials in vivo and animals indicated that Peimine and Peiminine, extracted from Thunbery Fritillary Bulb, have the function of reversing MDR of two different kinds of mechanisms. They can improve the cytotoxic of ADR to cancer cells by 5～10 folds under concentration of 10% cancer cell growth inhibitory rate. Peimine and Peiminine not only feather typical character of modifier of MDR, but also differ from other moldifiers such as Calcium channel blocker, Cyclosporines in chemical structure, they belong to cevine groups alkaloid, a subgroup of C-Nor-D-homosteroid alkaloid.

浙贝母是临床常用中药，体外及动物试验证明，浙贝母中的有效活性成分贝母甲素和贝母乙素具有逆转肿瘤细胞MDR的作用，而且能逆转两种不同机制的多药耐药肿瘤细胞的耐药性，在无明显细胞毒剂量下，可使阿霉素对耐药肿瘤细胞的杀伤活性提高5-10倍，不但具备明确的多药耐药逆转剂的特征，而且在化学结构上属异甾类生物碱中的瑟文类生物碱，完全不同于钙离子拮抗剂、免疫抑制剂和其它现有的耐药逆转剂，具有作用靶点宽、化学结构独特的特点。

objective effects of plant tannins,chebulinic acid and tellimagrandin i on chemically induced hemoglobin synthesis in k562 cells were investigated.methods the hemoglobin synthesis situation was assayed with benzidine staining.erythroid antigens glycophorin a expression on the surface of k562 cells was labeled by direct immunofluorescence using fluorescein isothiocyanate-conjugated anti-gpa antibodies.then flow cytometric analysis was performed to detect gpa expression levels on surface of the cells.results both chebulinic acid and tellimagrandin i could inhibit the hemoglobin synthesis of butyric acid and hemin-treated k562 cells in a concentration-dependant manner.however,the ba-induced k562 cells were more sensitive to two tannins than heroin-induced cells.conclusion chebulinic acid and tellimagrandin i have inhibitory effect on the erythroid differentiation.

目的 研究可水解单宁诃子酸和特里马素i对氯化高铁血红素和丁酸钠诱导k562细胞红系分化的影响。方法四甲基偶氮噻唑蓝法分析诃子酸和特里马素i对k562细胞生长的影响，联苯胺染色法检测血红蛋白合成情况，应用免疫荧光和流式细胞术检测血型糖蛋白a在细胞表面的表达。结果诃子酸和特里马素i在0.04～0.09？mmol／l浓度下均可显著抑制k562细胞的生长增殖。2种单宁化合物(0.002～0.01？mmol／l)可显著抑制丁酸钠诱导的k562细胞血红蛋白合成，2种单宁化合物(0.01～0.05？mmol／l)还可显著抑制氯化高铁血红素诱导的血红蛋白合成，特里马素i(0.01？mmol／l)还抑制丁酸钠诱导的gpa在细胞表面表达。结论诃子酸和特里马素i对红系分化有抑制作用。

Objective: To investigate the inhibitory effect of telomerase activity by chimeric oligonucleotide.

目的：研究嵌合寡核酸对端粒酶活性的抑制作用。

Methods Determination of DNJ by derivatization with 9-fluorenylmethyl chloroformate and followed by reversed-phase high-performance liquid chromatography and a fluorescence detector; the inhibitory curves on α-glucosidase at the enzymatic level and the activities to α-aglucosidase in vitro were observed in the everted sac experiment.

以氯甲酸药甲酯柱前衍生RP-HPLC荧光检测法对DNJ进行分析；在酶水平测定样品的α-糖苷酶抑制曲线，在离体水平用反转肠囊实验测定样品的α-糖苷酶抑制活性。

OBJECTIVE: To observe the inhibitory effects of hAS/293 and hES/293 cells on angiogenesis in chick chorioallantoic membrane.

目的：观察以基因工程技术构建的人血管抑素/293细胞和人内皮抑素/293细胞对鸡胚尿囊膜血管新生的抑制效应。

In chick chorioallantoic membrane assay, GLY also has inhibitory effect on angiogenesis.

而在鸡胚胎尿囊膜分析中，甘露饮也具有抑制血管新生的作用。

MethodsThe cells of human gastric cancer cell line SGC7901 was treated respectively with Chrysin at different concentration 10、20、40、80μM for 48h. The proliferation inhibitory rate was measured by MTT assay. Acridine orangestaining and flow cytometry were used to detect apoptosis. Western blot assay was used to detect the expression of apoptosis related genes NF拨B,Bcl2,Bax.

方法分别用10、20、40、80μM的ChR处理人胃癌细胞株SGC7901 48h，采用MTT比色法检测ChR对SGC7901细胞的增殖抑制效应；采用丫啶橙染色、流式细胞术检测ChR诱导SGC7901细胞凋亡的发生；应用Westernblot法检测凋亡相关基因NF拨B、Bcl2、Bax的蛋白表达，并用计算机图像分析软件进行半定量分析。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。