查询词典 inhibitory

Populations inhibitory effect of two kinds of bitter almond oil against Sitophilus zeamais Mots showed that the populations inhibitory effect of F1 and F′is decreased with the decrease of concentration, the populations inhibitory rate of F1 and F′is between 30% and 100%, 29.39% and 58.19% respectively.

种群抑制活性结果表明苦杏仁精油对玉米象F1代以及F′代的种群抑制活性随着处理浓度的降低而逐渐降低，两种处理的苦杏仁精油对玉米象F1代的种群抑制率范围在30%～100%之间，对F′代的种群抑制率范围在29.39%-58.19%之间。

Methods Mimicry and speculation on possible displaced amino acids in proper positions of peptide increased the biological effects of TNFR blocking peptide by compote modeling. The original peptide and its mutant were synthesized. The competitively inhibitory effects on green fluorescence protein-tumor necrosis factor fusion protein with TNFR were compared between original peptide and its mutant (receptor competitively inhibitory binding assays). The inhibitory effects on cytotoxicity were compared between original peptide and its mutant.

通过计算机模建，模拟并推测提高TNFR封闭肽生物学效应需置换的位点和氨基酸；合成原封闭肽和突变肽；受体竞争抑制结合实验比较原肽与突变肽对绿色荧光蛋白－肿瘤坏死因子融合蛋白结合TNFR的竞争抑制效应；细胞毒作用抑制实验比较原肽与突变肽对TNFR的封闭效应。

KIR bind corresponding HLA-Ⅰmay hame four results followed:1、When inhibitory KIR bind HLA-Ⅰand there has no activatory KIR bind it,cell isn\'t dissolve because inhibitory signal access was done;2、When activatory KIR bind corresponding HLA-Ⅰand there has no inhibitory KIR bind it,form activate signal,lead cell dissolve.3、If activatory or inhibitory receptor both bind HLA-Ⅰ,both signal access is make done,when activatory signal play the main role,NK cell still actived,lead target cell dissolve.4、If activatory or inhibitory receptor both bind HLA-Ⅰ,both signal access is make done,when inhibitory signal play the main role,or both signal access don\'t play,NK cell do not make effect.this is NK cell recognice nomal tissue.

与活化型KIR受体相比，抑制型KIR受体与HLA-Ⅰ类抗原结合的亲和性更强，当抑制型和活化型KIR受体识别和结合同一HLA-Ⅰ类抗原分子时，以抑制作用为主。KIR与相应HLA-Ⅰ结合后可能产生以下4种情况：①当抑制型KIR与HLA-Ⅰ结合而无活化型KIR与HLA-Ⅰ相互作用时，因抑制信号通路启动而不产生细胞溶解；②当活化型KIR与靶细胞表面的相应HLA-Ⅰ结合同时无抑制型KIR与HLA-Ⅰ的相互作用时，形成刺激信号通路，导致靶细胞溶解。

At pre-operation, post-operation 6 h, 3 d and 7 d detect the leave of plasm prethrombotic state molecular marker tissue factor, tissue factor pass inhibitory, thrombus precursor protein, plasminogen activator inhibitory-1(PAI-1), P-Selectin, Thrombin-Antithrombin complexes, D-dimer with ELISA, transmission immunity nephelometer. Results Malignant tumor patients, the levels of plasma TF, TpP, D-D in 6 h and 3 d of post-operation rose to peak value.

分别于术前、术后6 h3、d和7 d用ELISA、透射免疫比浊法检测其血浆血栓前状态分子标志物D-二聚体(D-dimer， D-D)、血栓前体蛋白(thrombus precursor protein， TpP)、凝血酶抗凝血酶复合物(thrombin-antithrombin complexes， TAT)、组织因子(tissue factor， TF)、P选择素(P-Selectin， P-S)、组织因子途径抑制物(tissue factor pass inhibitory， TFPI)、纤溶酶原激活物抑制物1(plasminogen activator inhibitory-1， PAI-1)的水平。

objective to observe the antitumor activities of different solution extracts of plumbago zeylanica l.in vitro.method mtt method was used to detect the inhibitory effects on four kinds of cancer cells.results chloroform extracts had significant inhibitory effects on the breast cancer cell(bre-04),the nerve cancer cell(n-04) and the lung cancer cell(lu-04),ic50 were 0.2699mg/ml and 0.2634mg/ml,0.4961mg/ml respectively.ic50 of chloroform extract on the hepg2 was 0.9379mg/ml.ic50 of petroleum ether extracts on bre-04,n-04,lu-04 and hepg2 was 0.5902mg/ml,0.5725mg/ml,0.7938mg/ml,0.6374mg/ml;ethyl acetate extracts had fairly inhibitory effects on the lu-04,ic50 was 0.7343mg/ml;n-butanol extracts and water-solubility extracts had notsignificant inhibitory effects on the four kinds of cancer cells.conclusion the antineoplastic effective parts of plumbago zeylanica l.were chloroform and petroleum ether extracts.

目的 探讨白花丹体外抗肿瘤作用的活性部位。方法 mtt染色法对白花丹五种溶剂提取物体外抗肿瘤活性进行了初步的研究。结果氯仿提取物对乳腺癌细胞（bre-04）、神经癌细胞（n-04）、肺癌细胞（lu-04）有较好的抑制生长作用，ic50分别为0.269 9 mg/ml、0.263 4 mg/ml、0.496 1 mg/ml，对肝癌细胞hepg2抑制作用差， ic50为0.937 9 mg/ml；白花丹石油醚提取部位对乳腺癌细胞（bre-04）、神经癌细胞（n-04）、肺癌细胞（lu-04）、肝癌细胞hepg2的ic50分别为0.590 2 mg/ml、0.572 5 mg/ml、0.793 8 mg/ml、0.637 4 mg/ml；乙酸乙酯提取物对肺癌细胞（lu-04）有一定的抑制作用，ic50为0.734 3 mg/ml；水溶性提取物以及正丁醇提取物无明显抑制肿瘤作用。结论白花丹氯仿提取部位、石油醚提取部位体外抗肿瘤作用较好，值得对其提取部位进一步分离纯化并研究其抗肿瘤作用机制。

At the primary screening test, 23 species of CHEs had significant inhibitory effects against the mycelium growth of Rhizoctonia solani with the inhibitory rates over 50%. Inhibitory effect of Celosia cristata L. extract reached up to 100%.

供试的126种中草药提取物中有23种提取物对立枯丝核菌菌丝生长具有显著的抑制作用，且抑菌作用大于50%，鸡冠花提取物的抑菌率达到100%。

Drug sensitive test and three-dimensional test220 strains of Pa were isolated from hospitalized patients between 2003 and 2007. K-B method was used to tested the susceptibility of 10 different antibiotics. IRPa was screened by testing the minimal inhibitory concentration of imipemem by using agar diluiion method.The susceptibility of these IRPa to the antibiotics was analysised. Three-dimensional test was used to identify the different kinds of beta lactamases from 220 strains of Pa.2.Carbarpenems hydrolytic enzyme genes and oprD2 gene were detectedamong the selected IRPa strains, PCR method was performed to detect carbapenemase genes which included GES、KPC、SPM、VIM、IMP、GIM gene and the oprD2 gene;Multiplex PCR were used to detect OXA genes and plasmid-mediated AmpC beta lactamase genes; The expression of the chromosomal AmpC beta lactamases and oprD2 genes in IRPa strains were analyzed by Real-time PCR.3.Identification and characterization of integronsIntegrase gene was detected by PCR, and the classification of integrons was performed by using restriction fragment length polymorphism.PCR was performed to detect the qacE△1-sull gene,and the gene cassetes which are located at variable region of integrons in the strains were detected to be positive.

方法1、药敏实验和三维实验收集2003～2007年临床分离的220株Pa，对这些菌株采用K-B法测定10种临床常用抗生素的药敏情况，同时采用琼脂稀释法检测亚胺培南的最低抑菌浓度(Minimal inhibitory concentration，MIC)，筛选出对亚胺培南耐药的铜绿假单胞菌，并分析其对其它抗生素的药物敏感率；采用三维实验的方法分析220株Pa产β内酰胺酶的类型。2、碳青霉烯类水解酶和oprD2蛋白的检测针对鉴定的IRPa菌株，采用普通PCR方法检测具有碳青霉烯水解作用的β内酰胺酶耐药基因(GES、KPC、SPM、VIM、IMP、GIM基因)和oprD2基因，采用多重PCR的方法检测OXA型基因和质粒携带的AmpC酶基因，用荧光定量RT-PCR方法检测oprD2蛋白基因表达情况；同时对产AmpC酶的Pa(25株，含IMP耐药和敏感株)用RT-PCR方法检测AmpC酶基因的表达量情况。3。

At the depigmentation assay, DH and EH show dose-dependently inhibitory activities against mushroom tyrosinase, and the IC50 is 5.697 and 5.256 mM, respectively, and show noncompetitively inhibitory modes in the present of tyrosine, but not DOPA. The control synthetic products, D and E, have no inhibitory effects on tyrosinase. Using tyrosinase activity staining in PAGE gels, both DH and EH show dose-dependently inhibitory pattern in the presence of tyrosine, while, EH also could suppress tyrosinase activity in the presence of DOPA.

而美白活性方面，以商品酪胺酸以商品酪胺酸酵素进行实验，当基质为酪胺酸时，发现DH与EH具浓度相关抑制效果，IC50分别为5.697与5.256 mM，且其相对於基质酪胺酸之抑制型态皆为非竞争型抑制，而其结构类似物之对照化合物D与E则不具此活性；但当基质为多巴时则皆不具此活性；利用原态PAGE电泳活性染色亦发现抑制酪胺酸酵素结果，但EH在基质为多巴时也能下降酪胺酸酵素活性。

The inhibitory effect of the volatilizable metabolites of two antagonists to P.funerea was analyzed in contrast with the inhibitory rate of the control . Gvirens , with the highest inhibitory rate of 59.7%, had more excellent and stable inhibitory activity and the effect was more relative with the time, but the inhibitory rate of B.firmus was less relative with the time and the inhibitory effect of B.firmus became stable after 72 hours.

两种颉抗菌代谢物中不同成份的抑菌效应试验表明，G.virens产生的多糖、粗脂肪、蛋白质对P.funerea孢子萌发有抑制作用，粗脂肪、蛋白质更明显，其中蛋白质抑制效果较稳定；B.firmus产生的粗脂肪可完全抑制P.funerea的孢子萌发，多糖、蛋白质抑制效果也较稳定，但多糖效果更好。

Results: fops had inhibitory effect on o 2 production in vitro, having a 50% of inhibitory concentration (ic50) of 3.866×10-6 g/ml, and a weak inhibitory effect on h2o2 production with a ic50 of l.668×10-3 g/ml but showed a potent inhibitory effect on the various free radicals produced by "respiratory burst" of human leukocyte. fops (20, 40, 80 mg/kg) increased the sod activity in myocardial tissue, liver and kidney of mice and decreased the mda content of myocardial tissue, liver, kidney and spleen of mice.

结果：在体外阿里红多糖可有效的清除o 2，其ic50为3.866×10-6；对h2o2的清除作用很弱，但能抑制人血嗜中性粒细胞&呼吸爆发&产生的多种自由基，ic50为1.668×10-3；阿里多红糖（20、40、80 mg/kg）可明显增加小鼠心脏和肝脏中sod的活性，其中剂量为40、80 mg/kg的阿里红多糖可明显增加肝脏中sod的活性，同时各给药组均可明显减少小鼠心脏、肝脏、肾脏和脾中mda的含量，与对照组相比较差异有统计学意义（p.05）。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。