查询词典 inhibitors

Both the inducers and inhibitors of CYP3A could affect the formation of pyrrolic metabolites, therefore may affect the clivorine-induced hepatotoxicity. The difference of clivorine- induced hepatotoxicity in racial and sex can be partly attributed to this metabolic difference in racial and sex. This phenomenon is worth to be notice.

这种代谢的种属差异是其在豚鼠、大鼠及人体内毒性的差异的原因，同时Clivorine在大鼠体内还存在着代谢的性别差异，其在大鼠体内毒性的性别差异可能与此有关，这种代谢的种属和性别差异导致毒性差异的现象值得引起重视。

Comparison of inhibitors for anti-polymerization of isoprene, such as NaNO2, p-tert-butylcatechol, N-methyl pyrrolidone and paradioxybenzene, was carried out using polymer segregation process and the results showed that TBC was the best one.

采用聚合物离析法比较了亚硝酸钠（NaNO2）、对叔丁基邻苯二酚、N-甲基吡咯烷酮、对苯二酚对异戊二烯的阻聚效果，发现TBC阻聚效果最好。

However, should a new virus emerge through reassortment, the M2 inhibitors might be effective.

但是如果出现重组的新毒株，M2离子通道抑制剂可能会有效。

Objectives: To study the relationship between matrix metalloproteinases and their inhibitors and the invasion and metastasis of human glioma, as well as the relationship between the expression of MMP-2 and TIMP-2 in human primary and recrudescent glioma and the grade of malignancy.

目的：探讨基质金属蛋白酶类与胶质细胞瘤浸润性生长之间的关系及其在胶质瘤复发中的作用，以及基质金属蛋白酶及其抑制因子(MMP-2、TIMP-2)的阳性表达与胶质细胞瘤病理分级及预后的关系。

More and more researchers have focused their attention on SAHH inhibitors because of the original chemistry structure, potent efficacy, and unique mechanisms.

SAHH抑制剂全新的化学结构、良好的作用效果和独特的作用靶点已引起国内外研究者广泛的兴趣。

Second, residues in the reactive site of the inhibitor were replaced by the consensus substrate recognition sequence of furin, namely, Arg at P_1, Lys at P_2, Arg at P_4 and Arg at P_6. In addition, the P_7 residue Asp was substituted with Ala to avoid possible electrostatic interference with furin inhibition. Finally, the extra N and C terminal residues beyond the doubly conjugated disulfide loops were further truncated. However, all resultant synthetic peptides were found to be temporary inhibitors of furin and kexin during a prolonged incubation, with the scissile peptide bond between P1 and P'1 cleaved to different extents by the enzymes.

高活性、低分子量的furin酶抑制剂有可能发展成为新型的抗细菌内毒素和抗病毒感染的药物，我们以绿豆胰蛋白酶抑制剂Lys片段长链22肽为模板，设计了一系列能抑制furin和kexin活性的突变体，采用如下三种方法逐步优化：一、去除Lys片段长链三对二硫键中的一对，用Ser替换Cys，减少可能存在的二硫键错误配对；二、抑制剂的活性中心根据furin底物的专一性逐步改变，即P1、P2、P4和P6位分别变为Arg、Lys、Arg和Arg，同时为了避免P7 Asp和P6 Arg之间可能存在的相互作用，将P7位Asp替换为Ala；三、将两对二硫键形成的双环的外面5个氨基酸残基去除。

Mono-and diglycerides contribute to shortening performance and act as staling inhibitors in bakery produces.

甘油单酸和甘油二酸在焙烤制品中赋予制品以松脆的性能，并起着抗老化剂的作用。

Mono-and diglycerides contribute to shortening performanceand act as staling inhibitors in bakery produces.

甘油单酸和甘油二酸在焙烤制品中赋予制品以松脆的性能，并起着抗老化剂的作用。

These include physical characteristics, such as repulsive forces resulting from the electronegative charge of both platelet and endothelial cell membranes, and biochemical attributes, such as the synthesis and release of inhibitors of platelet activation. Platelets respond rapidly to alterations of endothelial cells and to exposure of subendothelial structures by attaching firmly to the site of the lesion.

正常情况下，循环中的血小板与血管壁内皮细胞层紧密接触但不发生黏附，是因为血管内皮细胞具有一定的活性功能，包括一些物理特性如血小板和内皮细胞膜均带有负电荷产生相互排斥作用以及生化作用如合成和释放血小板活化抑制剂。

Among the three selected inhibitors, T-225 takes the best effect that it is difficult to generate the calcium gels, DETPMP takes subordinately.

通过对EDTMP和DETPMP的残余浓度分析探明：阻垢剂不仅是吸附于碳酸钙表面上，更多的是在碳酸钙析出的过程掺杂于其晶格中。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。