查询词典 inhibitors

McGill University - A psychopharmacology study has found that a new class of antidepressant drugs known as serotonin4 (5-HT4) receptor agonists may take effect four to seven times faster than traditional selective serotonin reuptake inhibitors.

麦吉尔大学-精神药理学研究发现，一类新的抗抑郁药称为s erotonin4（ 5 - h t4）受体激动剂可能生效6时5 6倍，速度比传统的选择性血清素再吸收抑制剂的。

The pyrethrin insecticides had lower toxicities to this insects, and the the corrected mortality of avermectin and the chitin synthesis inhibitors is lower than 40%, which's dose is 50 mg/kg.

微生物源杀虫剂阿维菌素和几丁质合成抑剂灭幼脲、杀铃脲和除虫脲对细胸金针虫幼虫的毒力较低，在剂量为50mg/kg土时，其校正死亡率均在40%以下。

5 H-Thiazolo [3,2-a] pyrimidine derivatives were found to be active acetylcholinesterase inhibitors.

5H-噻唑并[3，2-a]嘧啶类化合物是潜在的乙酰胆碱酯酶抑制剂。

The results were as follows: the activity of prawns was highest under the condition of pH 7.0, 35 ℃ using pyrocatechol as substrate; four inhibitors i.e ascorbic acid1 mg·mL~(-1, sodium sulphite2 mg·mL~(-1, phytic acid1 mL·L~(-1 and EDTA0.1 mg·mL~(-1 had some inhibiting effects on the PPO of prawns, in which the effect of phytic acid1 mL·L~(-1 was the best; the PPO activity of prawns increased gradurally during the storage period; the PPO activity of prawns was inhibited in vacuum environment, the lower the storing temperature was, the stronger the PPO activity was.

结果表明：以邻苯二酚为底物，虾PPO活性的最适pH为7。 0，最适温度为35 ℃；4种抑制剂(1 mg·mL-1抗坏血酸、2 mg·mL-1亚硫酸钠、1 mL·L-1植酸及0。 1 mg·mL-1EDTA)对南美白对虾PPO都表现出一定的抑制作用，以1 mL·L-1植酸抑制作用最强；南美白对虾在贮藏过程中PPO活性逐渐上升，真空环境中PPO活性受到抑制，贮藏温度越低，抑制作用越强。

Human bladder cancer cell line T24 was used, two different NF-kB inhibitors, pyrrolidine dithiocarbamate and dominant negative IkBα were used.

在人膀胱癌细胞系T24中，使用两个核转录因子kB抑制剂即显性失活IkBα质粒和二硫氨甲酸脂吡咯烷。

To investigated the relationship of the signal transduction pathway and other signal molucules, three signal transduction inhibitors were tested for their effects on L929 cell and the change of caspase activation. The inhitors include Staurosporine Quinacrine (PLA2 inhibitor) andVerapamil (Ca2+ channel blocker).

为了探讨γTNFβ和TNFβ诱导细胞凋亡的信号转导通路与其它信号分子的关系，我们检测了蛋白激酶C抑制剂Staurosporine、磷脂酶A2抑制剂Quinacrine和钙离子通道阻断剂Verapamil对γTNFβ及TNFβ杀伤L929细胞的影响及其伴随的Caspase8和Caspase3活性的变化。

METHODS: A simple and timesaving SOCl2 refluxed method was adopted to synthesize five quinazoline compounds as EGFR inhibitors.

我们改进了这种化合物的合成方法，用简单省时的SOCl2回流法合成五种喹唑啉类EGFR TK抑制剂。

The characteristics of quinazoline epidermal growth factor receptor inhibitors were briefly described in this paper, and the mechanism of receptor-tyrosine kinase inhibitor was also introduced. The synthesis of this kind of new compound was studied, and the synthetic route was redesigned and the method was modified.

本论文简述了受体酪氨酸激酶小分子抑制剂的发展概况，详细介绍了新型喹唑啉类表皮生长因子受体抑制剂，着重研究了该类化合物的合成，设计并打通了合成路线，同时又合成了25个新化合物。

3D-QSAR studies for one large set of quinazoline type epidermal growth factor receptor inhibitors were conducted using two types of molecular field analysis techniques: comparative molecular field analysis and comparative molecular similarity indices analysis .

采用了CoMFA和CoMSIA方法，进行了几类4-苯胺喹唑啉类抑制剂的三维定量构效关系的研究。

Special attention was directed toward finding inhibitors selective against KDR tyrosine kinase in order to ensure that the in vivo profile of a specific Src inhibitor could be determined. The 4-aminobenzodioxole quinazoline series gave compounds with excellent potency and selectivity.

一直以来，人们为了确保能够在体内测定Src酶专属性抑制剂的特性，把研究焦点放在对KDR酪氨酸激酶选择性的抑制剂的寻找上。4-氨基苯并间二氧五环喹唑啉系列化合物具有极好的效力和选择性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。