查询词典 inhibitor

RESULTS The results indicated that PCF could significantly increase the viability of thymocytes and enhance the activities of SOD, GSH-Px, CAT in cells. PCF decreased the amounts of ROS and the rate of apoptosis in cells. PCF inhibited the morpholog alteration of the thymocytes irradiated by UVB and maintained the ultrastructure of cells in normal. PCF attenuated UVB caused DNA fragmentation in thymocytes. While combined ERKs inhibitor yielded typical DNA fragmentation, co-treatment of thymocytes with PCF and JNKs and p38 kinase inhibitors completely blocked UVB-induced DNA fragmentation.

结果 PCF能显著提高UVB辐射后小鼠胸腺淋巴细胞的活性；提高胞浆中SOD、GSH-px、CAT的活性，降低ROS含量及细胞凋亡率；抑制UVB辐射所致的胸腺淋巴细胞凋亡的形态学改变，维持细胞的正常超微结构；抑制UVB所致的胸腺淋巴细胞DNA片段的出现；预先应用ERK抑制剂使DNA片段增加，给予JNK和P38抑制剂后协同PCF使DNA片段带减少。

Mechanical strains also regulated the protein and mRNA expression of several differentiation markers, as well as the activation of extracellular signal-regulated kinases, p38 MAP kinase and protein kinase B in a frequency-dependent manner. Furthermore, the inhibition of p38 pathway could block the strain-frequency induced the phenotype modulation of VSMCs, neither ERKs nor Akt. Frequency of mechanical strain, not conditioned medium, regulated the phenotype of VSMCs in a frequency-dependent manner. Rho-GDI alpha was suppressed by the mechanical strain at 1Hz.

采用免疫细胞化学法检测VSMCs形态和排列的变化；RT-PCR和Western blotting检测表型标志分子α-肌动蛋白、肌球蛋白重链(SM1/2)、肌动蛋白相关蛋白SM22α和调宁蛋白(h1-calponin)的mRNA和蛋白水平的变化；抑制剂或RNA干扰阻断可能的信号调节分子的活性或表达，包括p38、细胞外信号调节激酶1/(2extracellular signal-regulated kinases， ERK1/2)、蛋白激酶B和Rho-鸟苷酸解离抑制因子(Rho-guanine nucleotide dissociation inhibitor， Rho-GDI alpha)，研究了不同频率张应变对VSMCs表型转化的影响及其调节机制。

Results By incubating cardiomyocytes with bFGF, ERKs was activated and the cellular viability 〔(70.0±4.6)%in bFGF 10 ng group vs.(53.0±4.5)%in H/R group, P＜0.01） and the ATP content 〔(23.1±2.3) nmol/106 cells in bFGF 10 ng group vs.(12.3±2.1) nmol/106 cells in H/R group, P＜0.01〕 were increased, also the LDH leakage 〔(257.3±51.0) U/L in bFGF 10 ng group vs.(372.5±69.2) U/L in H/R group, P＜0.05〕, was decreased, then attenuation of H/R injury to cardiomyocytes was observed. PD098059, an inhibitor of upstream kinase of ERKs completely abolished the protective effects 〔viability (57.0±5.8)%,ATP content (15.1±2.6) nmol/106 cells,LDH activity in medium (325.5±59.0)U/L in PD098059 group vs. bFGF 10 ng group, P＜0.01, respectively〕.

结果 bFGF激活ERKs，并呈剂量依赖性减轻H/R所致心肌细胞损伤，表现为细胞存活率〔bFGF 10 ng组(70.0±4.6)%，H/R组(53.0±4.5)%，P＜0.01〕和细胞内ATP含量〔bFGF 10 ng组(23.1±2.3)nmol/106细胞，H/R组(12.3±2.1)nmol/106细胞，P＜0.01〕升高，细胞浆酶LDH漏出〔bFGF 10 ng组（257.3±51.0）U/L，H/R组（372.5±69.2）U/L，P＜0.05〕减少；ERKs上游激酶抑制剂PD098059完全消除上述保护作用〔PD098059组细胞存活率（57.0±5.8）%，ATP含量（15.1±2.6）nmol/106细胞，培养液中LDH活性（325.5±59.0）U/L，与bFGF 10 ng组比较均为P＜0.01〕。

The results of inhibitor addition to methanogens and to eubacteria showed that both groups of anaerobes especially methanogens played important role in the process of dechlorination.

加入甲烷菌抑制剂氯仿、真细菌抑制剂青霉素降低了PCP脱氯速率，表明甲烷菌对还原脱氯有重要影响，其它厌氧微生物也有不同程度的影响。

Solid goldthread extractive was investigated as an excellent natural green inhibitor .

从黄连中提取出的固体物质，可做为一种优良的天然绿色缓蚀剂。

Keywords goldthread extractive;natural green inhibitor;mild steel;electrochemical test;scanning electron microscopy

黄连提取物；天然绿色缓蚀剂；碳钢；电化学测试；扫描电子显微镜

Hlubocka Z, Umnerova V, Hellers, et al. Is mild essential hypertension without obvious organ complications and rish factors associated with increased levels of circulating markers of endothelial dysfunction, effect of ACE inhibitor therapy.

当心衰发生和发展时，机体交感神经和肾素-血管紧张素系统激活，AngⅡ生成明显增多，AngⅡ与血浆内皮功能失调密切相关，能够刺激血管内皮细胞衍生ET-1释放，引起血管张力升高［6，7］。

At the same time, DG4 can kill bacterium perfectly, the bactericidal ratio to sulfate-reducing bacteria and iron bacteria is 99.8% and 98.9%.According to the results, it can conclude that DG4 is a new highly effective corrosion and scale inhibitor and bactericide. Besides that, DG4 is more economic and environment-friendly.

DG4具有良好的缓蚀、阻垢和杀菌能力，是一种高效、环保型的多功能水处理剂，配方加以完善后能广泛的用于热电厂、中央空调等铜系设备的循环冷却水中。

Rotein kinas e C inhibitor. The major ganglioside of the

KC 抑制剂。神经系统主要的神经节苷脂。

Objective To investigate the effects of AA-861, the specific inhibitor of 5-lipoxygenase (5-LO), on the activation, proliferation and gene expression of kupffer cell and hepatic stellate cell.

目的 探讨5-脂氧合酶（5-LO）特异性抑制剂 AA-861对肝枯否细胞和星状细胞的活化、增殖和基因表达的影响。

Recall that, in the Kolmogorov axiomatization, measurable sets are the sets which have a probability or, in other words, the sets corresponding to yes/no questions that have a probabilistic answer.

延期开工的Kolmogorov宣布要衡量所有套职能有限许多坐标限制在于衡量子寅。换句话说，如果是/否的问题回答f可看的价值观念在许多最有限坐标，然后它有一个概率的答案。

The experimental results showed that the algorithm can filter singular points and remain fixity of the target edge.

实验表明：基于模糊理论的图像智能滤波方法比常规图像滤波方法运算量小，它既能去除奇异点，又能保持图像中目标的边缘不变性，具有很好的滤波效果。