查询词典 inhibitor

The invention also encompasses a pharmaceutical composition that is comprised of an EGFR kinase inhibitor and gemcitabine combination in combination with a pharmaceutically acceptable carrier.

本发明还涵盖药物组合物，其包含EGFR激酶抑制剂和吉西他滨组合，结合以药用载体。

The development, molecular base, Structure-activity relationship and classification of the COX-2 inhibitor as well as pharmic character , development status and trend of Lumiracoxib were reviewed in this paper.

本论文综述了COX-2抑制剂的发展、分子基础、构效关系、分类以及氯美昔布的药学特性和发展现状及趋势。

A trypsin inhibitor was isolated and purified from Phaseolus vulgaris, and partial characterization of PVTI was studied.

本论文以菜豆的一个栽培品种紫花芸豆为材料，从中分离纯化胰蛋白酶抑制剂PVTI，并对其部分性质进行了研究。

Critically, the combination of a tyrosine kinase inhibitor, i.e., IM, nilotinib, or dasatinib, with inhibitors of autophagy resulted in near complete elimination of phenotypically and functionally defined CML stem cells.

关键的是，联合应用酪氨酸激酶抑制剂，如IM、尼洛替尼、达沙替尼和自噬抑制剂可几近全部消除表型及功能定义的CML干细胞。

Biochemical and Biological Properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a Mechanism-Based Inhibitor of Fatty Acid Amide Hydrolase Technical Communication

4--哌嗪-1-羧基酸苯胺的生化和生物学属性，脂肪酸氨基水解酶的一个基于机制的抑制剂

Scale inhibitor ; phosphonic acid ; water soluble polymer

阻垢剂；有机磷酸；水溶性聚合物

Tetrahydroisowuinolin derivatives and phthalide derivatives were designed and synthesized on the basis of a PDE4 inhibitor pharmacophore model set up through computer simulation. Some tetrahydroisowuinolin derivatives synthesized were evaluated on their activity against PDE4 for study on the structure-activity relationship.(7-cyclopentyloxy)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155) and Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate (170) showed good activity against PDE4, which were chosen as the lead compounds to design and synthesize another analogs in order to develop selective PDE4 inhibitors with better activity.

分别设计合成了以四氢异喹啉和氨基苯酞为骨架的两类小分子杂环化合物，并对部分四氢异喹啉衍生物测试了其相关的生物活性，初步确定了其构效关系，发现了两个对PDE4有较好抑制活性的先导化合物(7-cyclopentyloxy)-6-methoxy-3，4-dihydroisoquinolin-2(1H)-yl(4-hydroxy-3-methoxyphenyl)methanone (155)和Methyl 7--6-methoxy-2-(4-methoxy- benzoyl)-1-phenyl-1，2，3，4-tetrahydroisoquinoline-3-carboxylate (170)。

The number of proteinase inhibitor genes required to protect the pathogens from plant proteases is also expanded in the Phytophthora genomes.

有多少蛋白酶抑制剂基因要求，以保护病原体从植物蛋白酶，也扩大了在疫霉基因组中。

The synergism ratios of piperonyl butoxide to alpha-cypermethrin in these three strains were similar(about 20-fold), which suggested metabolic detoxification probably confers about 20-fold inherent resistance in the B-type whitefly, as PBO is a mixed function oxygenase and esterase inhibitor and glutathione S-transferase is not affinity to resistance in B. tabaci. The synergism ratio of triphenyl phosphate to alpha-cypermethrin in the NJ strain was 12-fold, which implied the synergism of PBO in the B-type whitefly is mainly due to inhibiting esterase activity.

增效试验表明PBO对这三个品系的增效作用均为20倍左右，因为在烟粉虱中PBO即是多功能氧化酶抑制剂，也是酯酶抑制剂，而谷胱甘肽S-转移酶与抗性无关，因此推断代谢酶在B型烟粉虱对高效氯氰菊酯的抗性发展中起到的相对作用可能为20倍左右，而且这种抗性是B型烟粉虱天生的；TPP对NJ品系的增效作用为12倍，说明PBO增效作用主要是由于抑制酯酶而引起的，即代谢抗性大部分由酯酶所贡献。

Shale inhibitor GLY- 1 is a polyvalent alcohol, prepared from polyglycerol. Mud system formulated with GLY- 1, and other chemicals can retarding the hydration and swelling of shales.

以多元醇GLY-1抑制剂为主，辅配降失水剂、增粘剂等常用处理剂的钻井液体系，能显著降低泥页岩的水化分散和水化膨胀作用，具有较好的流变性、润滑性、造壁性及抗无机钠盐、钙盐、石膏污染的能力。

Recall that, in the Kolmogorov axiomatization, measurable sets are the sets which have a probability or, in other words, the sets corresponding to yes/no questions that have a probabilistic answer.

延期开工的Kolmogorov宣布要衡量所有套职能有限许多坐标限制在于衡量子寅。换句话说，如果是/否的问题回答f可看的价值观念在许多最有限坐标，然后它有一个概率的答案。

The experimental results showed that the algorithm can filter singular points and remain fixity of the target edge.

实验表明：基于模糊理论的图像智能滤波方法比常规图像滤波方法运算量小，它既能去除奇异点，又能保持图像中目标的边缘不变性，具有很好的滤波效果。