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Antitrypsin (α1-AT) is the major proteinase inhibitor and takes part in many metabolic processes in human bo...

1抗胰蛋白酶（α1-AT）是人体内主要的蛋白酶抑制剂，它参与机体的多种代谢过程。

Inflammation upregulates alpha1 antitrypsin, which, with respect to the protein C pathway, or with respect to coagulation, primarily, is an inhibitor of APC and may also downregulate heparin.

炎症反应可上调α1抗胰蛋白酶，它与蛋白C通路有关，或者说与血凝有关，但主要是APC的抑制剂，并可下调肝素。

Alpha-1 antitrypsin is the most abundant circulating protease inhibitor in the body, Dr. Lomas said. Its most common deficiency mutation is the Z allele, where the amino acid lysine is exchanged for glutamic acid at position 342 in the polypeptide chain (Glu342Lys). About 1 in 1700 whites of northern European descent are homozygotes for this mutation and thus have plasma antitrypsin levels that are 10% to 15% below normal, he said.

Lomas博士表示，甲一型抗胰蛋白酵素是身体内最充分的循环蛋白酶抑制剂，最常见的缺损突变在Z对偶基因，该处的胺基酸 lysine与麸氨酸在多胜肽链的第342位置交换(Glu342Lys)；北欧血统白人每1，700人有1人是此一突变的同合子，因此血浆抗胰蛋白酵素值比正常低10%到15%。

Arbutin – another inhibitor of tyrosinase, it works in a similar manner to hydroquinone, but without the side effects.

熊果苷 -另一种酪氨酸酶抑制剂，它在一个类似的方式，对苯二酚，但没有副作用。

The results obtained are as follows:(1) intrarenal artery injection of capsaicin (20, 40, and 60 nmol/kg) increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with ruthenium red (40 mmol/kg), a capsaicin receptor antagonist, completely abolished the effect of capsaicin; and (3) pretreatment with a nitric oxide synthase inhibitor L-NAME ( N6-nitro-L-arginine methylester, 0.1 mmol/kg), significantly enhanced the ARNA response to capsaicin.

结果表明：(1)肾动脉内注射辣椒素20、40和60nmol/kg可呈剂量依赖性地兴奋肾传入纤维的活动，而动脉血压不变；(2)静脉内预先应用辣椒素受体阻断剂钌红(40 mmok/kg)，可完全阻断辣椒素对肾传入纤维的兴奋作用。(3)静脉内预先注射一氧化氮合酶抑制剂L-NAME(0.1 mmok/kg)，能延长并增强肾传入神经对辣椒素的反应。

The results obtained are as follows:(1) injection of 50, 100, and 200 nmol/kg adenosine into the renal artery increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2) pretreatment with 8-cyclopenthl -1,3-dipropylxanthine (DPCPX, 160 nmol/kg), an adenosine A1 receptor antagonist, partly abolished the effect of adenosine; and (3) pretreatment with a nitric oxide synthase inhibitor N w-nitro- L -arginine methylester (L -NAME, 0.1 mmol/kg) significantly enhanced the ARNA response to adenosine.

结果表明：(1)肾动脉内注射50， 100和200 nmol/kg腺苷可呈剂量依赖性地兴奋肾神经传入纤维的活动，而动脉血压不变。(2)肾动脉内预先应用选择性腺苷A1受体阻断剂DPCPX (160 nmol/kg)，可部分阻断腺苷对肾神经传入纤维的兴奋作用。(3)静脉应用一氧化氮合酶抑制剂 L -NAME(0.1 mmol/kg)预处理，延长并增强了肾神经传入纤维对腺苷的反应。

The results obtained are as follows:(1) injection of 50, 100, and 200 nmol/kg adenosine into the renal artery increased the renal afferent nerve activity in a dose-dependent manner with unchanged arterial pressure;(2)pretreatment with 8-cyclopenthl-1,3-dipropylxanthine (DPCPX, 160 nmo//kg), an adenosine A1 receptor antagonist, partly abolished the effect of adenosine; and (3) pretreatment with a nitric oxide synthase inhibitor Nω-nitro-L-arginine methylester (L-NAME, 0.1 mmol/kg)significantly enhanced the ARNA response to adenosine.

结果表明：(1)肾动脉内注射50，100和200nmol/kg腺苷可呈剂量依赖性地兴奋肾神经传入纤维的活动，而动脉血压不变。(2)肾动脉内预先应用选择性腺苷A1受体阻断剂DPCPX(160nmol/kg)，可部分阻断腺苷对肾神经传入纤维的兴奋作用。(3)静脉应用一氧化氮合酶抑制剂L-NAME(0.1mmol/kg)预处理，延长并增强了肾神经传入纤维对腺苷的反应。

The research status and development trend of several functional additives for internal combustion engine oil such as metallic detergent,ashless dispersant,antioxidant and corrosion inhibitor,friction modifier are presented.

介绍了金属清净剂、无灰分散剂、抗氧抗腐剂、摩擦改进剂等内燃机油几大功能添加剂的研究现状及发展趋势，并提出了今后润滑油添加剂的研究方向。

Pepstatin,which contains the novel amino acid statine,is a natural pentapeptide isolated from natrue product.It is a good inhibitor of most aspartyl proteases with a K_i in the nanomolar range.

从天然产物中分离得到的Pepstine对大多数天冬氨酸蛋白酶的抑制率达纳摩尔级，但其选择性差、溶解性弱。

Methods The level of serum and urinary tissue-type plasminogen activator and plasminogen activator inhibitor-1 (PAT-1) were measured in 38 patients with chronic glomerulonephritis, 28 patients with nephropathy syndrome, 36 patients with chronic renal failure and 20 healthy subjects by means of enzyme-linked immunosorbent assary. The relationship among urinary t-PA, PAI-l and serum t-PA, PAT-1, urinary protein, serum creatinine were also observed. Results Levels of serum t-PA, PAI-1 in chronic kidney diseases increased remarkably compared with control group.

选择38例慢性肾小球肾炎，28例肾病综合征，36例非透析治疗的慢性肾功能不全和20例正常对照作为研究对象，应用ELISA法检测血清和尿液中组织型纤溶酶原激活剂和纤溶酶原激活物抑制剂－1(PAI-1)的浓度，同时分析尿中t-PA和PAI-1的水平与血t-PA、PAI-1、血肌酐和24h尿蛋白总量之间相关性。

Recall that, in the Kolmogorov axiomatization, measurable sets are the sets which have a probability or, in other words, the sets corresponding to yes/no questions that have a probabilistic answer.

延期开工的Kolmogorov宣布要衡量所有套职能有限许多坐标限制在于衡量子寅。换句话说，如果是/否的问题回答f可看的价值观念在许多最有限坐标，然后它有一个概率的答案。

The experimental results showed that the algorithm can filter singular points and remain fixity of the target edge.

实验表明：基于模糊理论的图像智能滤波方法比常规图像滤波方法运算量小，它既能去除奇异点，又能保持图像中目标的边缘不变性，具有很好的滤波效果。