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inhibited factor相关的网络例句

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Additionally XBP1 mRNA which functioned as centrally regulating molecule during ER stress was spliced partially,while it was completely spliced in positive control cells and unspliced in H7721.These results gave the proof that blocking expression of GnT-V caused H7721"s ER stress and response was more weak than that caused by DTT. It may be the chronic process.Additionally,previous studies reported that the ds-RNA may activate the kinase PKR which phosphorylated eIF2 α and inhibited synthesis of proteins.In this paper the antisense cDNA of GnT-V was integrated with GnT-V-AS/H7721"s gene and functioned through the binding of antisense RNA and mRNA of GnT-V.Additionally,the integration of GnT-V cDNA in genome also may be a non-specific factor.

对这三种ER stress关键分子的检测发现:和阴性细胞相比较,实验细胞中BIP的表达无论是蛋白水平还是转录水平都有明显的上调,但上调程度都要低于DTT处理的ER stress阳性细胞;XBP-1 mRNA在实验细胞中部分被剪接,在阳性细胞中XBP-1 mRNA完全被剪接,而在阴性细胞中其以非剪接形态存在;此外和DTT处理的ER stress阳性细胞相似,实验细胞中的PERK发生磷酸化,表明ER stress过程中通过磷酸化eIF2α抑制蛋白合成机制的活化,这和芯片所检测到的GnT-V-AS/H7721细胞蛋白合成系统水平下调相一致。

The main work of our research was to study the effects of the combination of enhanced UV-B radiation 0.35w·m~(-2 and Cadmium 1umol·L~(-1 on the growth, photosynthesis, elements absorption and relocation in mung bean seedlings at the initial stage of growth, and the involving mechanisms about the change of photosynthesis under the different treatments were studied also. It was shown that the heights root length, lateral root length, lateral root number, area of leaves, dry/fresh weight of the overground parts and underground part were all inhibited by the single factor and combinative factors.

本文以0.35w·m~(-2)剂量的UV-B模拟增强UV-B辐射和1μmol·L~(-1)Cd~(2+)模拟Cd~(2+)污染,研究了增强UV-B辐射和Cd~(2+)及其复合处理对绿豆幼苗生长、光合作用以及元素吸收和分配的影响,并对不同处理条件下绿豆幼苗光合作用的变化机制进行了比较深入的分析,获得结果如下:增强UV-B辐射和Cd~(2+)及其复合处理8天,绿豆幼苗植株高度、根长、侧根长、侧根数、叶面积、地上部分干/鲜重和根系干/鲜重均下降。

The stimulatory effect on the MMP-13 promoter was partially inhibited by mutation of the osteoblast-specific element 2 (OSE-2) binding site ⑸ Core binding factor-1 (Cbfa-1) expression peaked at 7 days ⑹ of differentiation, and was phosphorylated by PKG in itro.

免疫组织学检查揭示在17天大的embryo iNOS缺乏的老鼠MMP-13和Cfba-1表达水平均降低。Cfba-1 mRNA的沉默阻滞MMP-13的表达,不影响内源性的NO产生,肯定了他在MC3T3-E1细胞中NO诱导的MMP-13的表达中的作用。

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