查询词典 inflammatory
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Keywords Mytilus crassitesta Lischlk;Lyprinol;fatty acids;nutritional evaluation;soft capsule;stability;anti-inflammatory activity
Article From 浙江大学;食品科学硕士论文 2007年度厚壳贻贝; Lyprinol;脂肪酸;营养评价;软胶囊;稳定性;抗炎活性
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The anti-inflammatory activity of the Mytilus crassitesta lipid extract was comparative with Lyprinol, a lipid extract of New Zealand green-lipped mussel.
结果表明厚壳贻贝脂溶性提取物具有很强的抗炎生物活性,能显著抑制大鼠棉球肉芽肿和大鼠佐剂性关节炎原发性和继发性症状,其抗炎生物活性比新西兰绿唇贻贝脂溶性提取物稍低或与之相当。
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Results The tumor consisted of spindle cells,large number of chronic inflammatory cells and myxoid background with delicate vasculature.
结果 肿瘤由梭形细胞、大量慢性炎性细胞及黏液血管样背景构成。
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Determination of functional components in foods and Chinese herbs as well as evaluation of biological activity – Both foods and Chinese herbs investigated include soybean, Ziziphus jujuba , Lycium barbarum , Gynostemma pentaphyllum , Taraxacum formosanum , Rhinacanthus nasutus , Scutellaria barbata , etc. Functional components investigated include carotenoid, chlorophyll, flavonoid, phenolic acid, polysaccharide, saponin, isoflavone, etc. In my lab we have developed many LC-MS methods for determination of these components and proved their antiproliferation effect on cancer cells and anti-inflammatory activity.
食品及中草药有效成分测定及其对生物活性的影响-探讨的食品包括大豆、蕃茄、芒果等等,中草药包括红枣、枸杞、七叶胆、蒲公英、仙鹤灵芝草、半枝莲等等,有效成分则包括类胡萝卜素、叶绿素、类黄酮、酚酸、多醣、皂苷、异黄酮等等,本实验室已成功开发多种LC-MS方法测定这些成分并证实这些成分具有抑制癌细胞增生及抗发炎的功效,已有多篇论文发表於国际著名期刊。
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But there were a large numbers of inflammatory cells and necrotic tissues around the xenogenic bone.
结果:支架组材料周围未见明显的炎症反应,而异种骨组骨组织周围有大量的炎细胞浸润,并有坏死组织。
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Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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Magnetic resonance imaging ; liver neoplasma ; inflammatory pseudotumor
磁共振成像;肝肿瘤;炎性假瘤
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The change of the control grouph histomorphology was clear: the inerassation of synovial lining cells, the infiltration of Inflammatory cells and the erosion of nephelium of blood vessels on bones.
模型组大鼠组织形态学改变明显:关节滑膜衬里层细胞明显增犀,炎性细胞浸润,血管翳组织侵蚀骨组织等;而给药组组织形态学改变显著减轻。
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At present, most of scholars think that the deposit of β-amyloid make the activation of neuroglial cells, which trigger the chronic inflammatory reactivity in AD brain.
目前多数学者认为:β-淀粉样蛋白沉积使得神经胶质细胞活化引起脑内慢性炎症反应可能是AD发病的核心病理机制之一。
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